A5100639672- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Orthopedic Surgery and Rehabilitation
- Problem and Project Based Learning
- Tendon Structure and Treatment
- Toxin Mechanisms and Immunotoxins
- Bone fractures and treatments
- Innovations in Medical Education
- Nerve injury and regeneration
- Sarcoma Diagnosis and Treatment
- Pharmaceutical and Antibiotic Environmental Impacts
- Advanced Nanomaterials in Catalysis
- Thyroid Cancer Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cervical and Thoracic Myelopathy
- Retinal Diseases and Treatments
- Pain Mechanisms and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Elbow and Forearm Trauma Treatment
- Scoliosis diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
Fourth People's Hospital of Sichuan Province
2023-2025
University of Electronic Science and Technology of China
2024-2025
Union Hospital
2020-2024
Jilin University
2015-2024
Center for High Pressure Science & Technology Advanced Research
2024
North Sichuan Medical University
2023
Nanchong Central Hospital
2023
Union Hospital
2015-2022
Wannan Medical College
2020-2022
Xilinx (United States)
2020
Lateral lumbar interbody fusion (LLIF) is a popular, minimally invasive technique that used to address challenging multilevel degenerative spinal diseases. It remains controversial whether supplemental instrumentation should be added for LLIF. In this study, we compared the kinematic stability afforded by stand-alone lateral cages with those supplemented bilateral pedicle screws and rods (PSR), unilateral PSR, or plate (LP) fixation using finite-element (FE) model of multi-level LLIF...
Previous studies have demonstrated that chronic cold exposure activates the sympathetic nervous system, increases energy expenditure, improves glucose tolerance, enhances insulin sensitivity, and stimulates uptake in peripheral tissues [brown white adipose (BAT WAT) muscles] of normal rats. The goal present was to test whether selective β 3 -adrenergic agonist CL-316243 (CL) would mimic beneficial effects lean obese ZDF/Gmi- fa male (ZDF) rats, a new model type II diabetes. In ZDF infusion...
The effect of platelet-rich plasma on nerve regeneration remains controversial. In this study, we established a rabbit model sciatic small-gap defects with preserved epineurium and then filled the gaps plasma. Twenty-eight rabbits were divided into following groups (7 rabbits/group): model, low-concentration PRP (2.5-3.5-fold concentration whole blood platelets), medium-concentration (4.5-6.5-fold high-concentration (7.5-8.5-fold platelets). Electrophysiological histomorphometrical...
We constructed a 1T-MoS 2 /Ni 3 S 4 heterostructure which promotes water dissociation and optimizes hydrogen adsorption for electrocatalysts then endows it with exceptional alkaline HER catalytic activity comparable to commercial Pt/C.
Abstract Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome, affecting a large proportion of general population. Genetic susceptibility has been implicated in CTS, but causative genes remain elusive. Here, we report identification two mutations cartilage oligomeric matrix protein (COMP) that segregate with CTS families or without multiple epiphyseal dysplasia (MED). Both impair secretion COMP by tenocytes, mutation associated MED also perturbs its...
Abstract An improved one-shot thermoplastic elastomer reinforced shape memory polymer (SMP) four-dimensional (4D) printing method for hybrid composite samples is proposed. Through the new reinforcement of interlayer overlapping, problem inability to bond between polylactic acid (PLA) and polyurethane (TPU) overcome, materials had excellent bonding properties. The feature manufacturing that interface PLA TPU has continuous overlapping layers, boundary wavy. Herein complex multi-material space...
It is important for future clinical applications to design and synthesize multipurpose scaffolding materials bone tissue engineering with high osteogenic induction MRI capability. In the present study, we synthesized Ce/Gd@HA by co-doping Ce3+ Gd3+ into hydroxyapatite (HA) using a hydrothermal synthesis method, then composites were combining nanoparticles polylactic-co-glycolic acid (PLGA) investigate whether implanted Ce/Gd@HA/PLGA could promote osteoblast viability, leading tibia repair of...
OBJECTIVE Obesity and low-back pain associated with degenerative spondylosis or spondylolisthesis are common comorbid conditions. Many patients report that the disability lumbar disease key factors in their inability to lose weight. The aim of this retrospective study was determine if there is an association between improved functional status weight loss following a successful transforaminal interbody fusion (TLIF) procedure. METHODS A cohort who underwent single-level TLIF performed....
Minimally invasive lateral lumbar interbody fusion (LLIF) is traditionally performed with biplanar fluoroscopy. Recent literature demonstrates that intraoperative cone-beam computed tomography combined spinal navigation can be safely utilized for localization and cage placement in LLIF.To evaluate the accuracy safety of using LLIF, as well to radiation exposure surgeon staff during procedure.The authors a retrospective analysis prospectively acquired database patients undergoing LLIF...
Abstract Animal models of peripheral nerve injury (PNI) serve as the fundamental basis for investigations injury, regeneration, and neuropathic pain. The properties such models, including intensity duration, significantly influence subsequent pathological changes, pain development, therapeutic efficacy. However, precise control over duration remains challenging within existing animal thereby impeding accurate comparative assessments relevant cases. Here, a new model that provides...
Cholecystokinin-2 receptor (CCK2R) has been proven to be a specific biomarker for colorectal malignancies. Immunotoxins are valuable class of immunotherapy agents consisting targeting element and bacterial or plant toxin. Previous work demonstrated that CCK2R is good therapeutic strategy the treatment cancer (CRC). In present study, we developed new version CCK2R-targeting immunotoxin GD9P using targeted peptide, GD9, as binding motif truncated Pseudomonas exotoxin A (PE38) cytokiller....