A5101826846- Spine and Intervertebral Disc Pathology
- Head and Neck Surgical Oncology
- Spinal Fractures and Fixation Techniques
- Brain Metastases and Treatment
- Pelvic and Acetabular Injuries
- Cervical and Thoracic Myelopathy
- Head and Neck Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Oral and Maxillofacial Pathology
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Advanced Radiotherapy Techniques
- Gastric Cancer Management and Outcomes
- Salivary Gland Tumors Diagnosis and Treatment
- Healthcare and Venom Research
- Medical Imaging Techniques and Applications
- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Lung Cancer Research Studies
- Trigeminal Neuralgia and Treatments
- Pregnancy-related medical research
- Scoliosis diagnosis and treatment
- Respiratory Support and Mechanisms
- Acupuncture Treatment Research Studies
Wuhan Third Hospital
2025
Tongren Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2023
Third Affiliated Hospital of Guangzhou Medical University
2021-2022
Guangzhou Medical University
2021-2022
Fudan University
2021
Shanghai Changzheng Hospital
2018-2021
University of Cincinnati Medical Center
2021
Huizhou Central People's Hospital
2017-2021
Pudong Medical Center
2021
Lateral lumbar interbody fusion (LLIF) is a popular, minimally invasive technique that used to address challenging multilevel degenerative spinal diseases. It remains controversial whether supplemental instrumentation should be added for LLIF. In this study, we compared the kinematic stability afforded by stand-alone lateral cages with those supplemented bilateral pedicle screws and rods (PSR), unilateral PSR, or plate (LP) fixation using finite-element (FE) model of multi-level LLIF...
Persistent chronic inflammation of obstructive pulmonary disease (COPD) is associated with poor outcomes and frequently results in acute exacerbation. Predicting the number exacerbations important. Because interleukin 6 (IL-6) plays an important role inducing maintaining inflammation, we sought to observe whether IL-6 measurement can predict frequency exacerbation COPD.We reviewed serum concentrations stable COPD patients from January 2016 December 2017 statistically analyzed them determine...
Abstract Background To evaluate the efficacy and outcomes of hypofractionated stereotactic radiotherapy (HSRT) for brain metastases > 3 cm. Methods From March 2003 to October 2009, 40 patients with larger than cm were treated by HSRT. HSRT was applied in 29 primary treatment 11 rescue. Single metastasis detected 21 patients. Whole incorporated into 10 treatment. boosts 23 The diameters ranged from 3.1 5.5 (median, 4.1 cm). median prescribed dose (not including boosts) Gy (range, 20-53 Gy)...
Heart failure (HF), a major cause of morbidity and mortality worldwide, is prevalent among individuals with H-type hypertension, which marked by high blood pressure elevated homocysteine. The Triglyceride-Glucose (TyG) index, surrogate for insulin resistance, may predict HF in this group, though its specific role requires clarification. This study explores the TyG index's relationship incidence hypertension patients. A retrospective cohort was conducted on 1200 patients at Wuhan Third...
Abstract Background The purpose of this study was to determine the features elderly patient with nasopharyngeal carcinoma (NPC). Methods medical records 212 patients NPC, aged ≥65 years, and receiving radiotherapy were retrospectively reviewed. Comorbidity rated using Charlson Index (CCI). Results Twenty‐four (11.3%) scored ≥3 188 (88.7%) <3 by CCI. median actuarial irradiated dose nasopharynx 72 Gy (range, 20–94 Gy) 87.3% >70 Gy. One hundred fifty‐four had stage III/IV disease. local...
In patients with gastric cancer (GC), peritoneal metastasis is an indication of the end stage and often indicates a poor outcome. The diagnosis metastasis, especially occult (OPM), remains challenge for surgeons. This study was designed to explore relationship between OPM clinicopathological characteristics preoperative hematological parameters in GC develop nomogram predict probability before surgery.A total 672 from our center were included, including 583 OPM-negative 89 OPM-positive...
Discography can increase disc degeneration, but the influence of different discography variables on degeneration discs has not been reported. The aim this study was to investigate effects needle diameter, type contrast agent and volume degeneration.Three separate experiments examined agent. Coccygeal (Co7-10) adult male rats were used. X-rays used detect height index at 1, 2 4 weeks after procedure. MRI changes in structure signal intensity IVD Disc water content histology measured...
Abstract Background Esthesioneuroblastoma (ENB) is a rare malignant neoplasm. Currently, no consistent and universal staging system for ENB exists. The aim of this study to propose TNM‐based classification. Subjects methods Hundred forty‐two patients from our institution, with pathologically confirmed between July 1978 December 2018, were reviewed. All restaged according the Kadish stage, Morita stage American Joint Committee on Cancer (AJCC) T classification clinical radiological data....
The present study aimed to investigate the association between serum SIRT1 protein and severity of spinal cord injury (SCI) as well neurological recovery in mice. In this study, wild-type (WT), Mx1-Cre+ SIRT1loxP/loxP (Mx1), LCK-Cre+SIRT1loxP/loxP (LCK) mice were subjected sham surgery, mild, moderate, or severe SCI, respectively. was collected at intervals 12 h, 1 day (d), 3 d, 5 7 10 14 21 d after injury. locomotor function all animals assessed using Basso mouse scale (BMS) proteins...
To observe the impacts of thermosensitive moxibustion (TSM) on expressions nitric oxide (NO), typeⅠdisintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4), typeⅡcollagen proteoglycan (PG) in rabbit models knee osteoarthritis (KOA) explore mechanism TSM KOA.A total 42 Japanese long-eared male rabbits were divided into a blank group (6 rabbits), model (24 rabbits) sham-operation according to random number table. In group, fed normally. groups, papain injection was given...
To analyze the failure patterns in patients with different histological subtypes of sinonasal malignancies (SNMs).Retrospectively gathered data.Academic university hospital.Patients SNMs treated at a tertiary referral center between January 1999 and 2019 were included. We assessed within subtypes.The study included 897 patients. The median follow-up time was 100 months. Adenoid cystic carcinoma (ACC) had moderate risk developing local recurrence (LR) distant metastasis (DM). Compared ACC,...
Background: To evaluate the efficacy and outcomes of hypofractionated stereotactic radiotherapy (HSRT) for brain metastases > 3 cm.
Objective To investigate the clinical features,treatment outcome and prognosis of pa tients with nasopharyngeal adenoid cystic carcinoma(ACC).Methods From March 1963 to August 2002, 33 patients ACC were retrospectively reviewed.Among them,13 received multimedality therapy(S + R in 9 +S 4) remaining 20 radiotherapy alone.The interval between first visit diagnosis was 12 months(1.0-36.4 months).The misdiagnosis rate 55% (18/33),with most common error otitis media.The symptoms similar those...
Objective To investigate the clinical outcomes using posterior percutaneous endoscopic cervical discectomy (PECD) for single level spondylotic radiculopathy (CSR). Methods From October 2015 to June 2016, 33 patients (23 men, 10 women, mean age 54.0 years, range from 30 85 years) who had CSR were treated by PECD, and medical records reviewed. All followed up an average of 13.5±4.6 months (range 12 22 months). The operation related parameters (operation time, estimated blood loss,...
Objective To analyze the relationship between tumor deposits(TD) and clinicopathological features of locally advanced gastric cancer(LAGC) patients. Methods The characteristics 300 LAGC patients undergoing radical gastrectomy in Renmin Hospital Wuhan University from Jan 2014 to Jul 2017 were collected. The prognosis TD status analyzed retrospectively. Results TD positive 65(21.7%) patients. Univariate analysis showed that depth invasion, lymph node metastasis, pTNM stage, size,...
To study the effect of intradiscal injection simvastatin on discogenic pain in rats and its possible mechanism, 30 adult female were used this experiment. Twenty randomly divided into sham operation group (Control group), intervertebral disk degeneration (DDD + hydrogel GEL SIM group). The mechanical threshold cold sensation measured. contents NF-kappa B1, RelA, GAP43, SP, CGRP, TRPM 8, IL-1β, TNF-α (IVD), corresponding dorsal root ganglion (DRG) plantar skin GAP43 8 quantitatively detected...