Pankaj Kumar

ORCID: 0000-0003-2336-1493
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About
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Research Areas
  • Synthesis and biological activity
  • Drug Solubulity and Delivery Systems
  • Cancer therapeutics and mechanisms
  • Bioactive Compounds and Antitumor Agents
  • Advanced Drug Delivery Systems
  • Hydrogels: synthesis, properties, applications
  • Electrospun Nanofibers in Biomedical Applications
  • Analytical Methods in Pharmaceuticals
  • Food composition and properties
  • Heat Transfer and Boiling Studies
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Inflammatory mediators and NSAID effects
  • Nanocomposite Films for Food Packaging
  • Sensory Analysis and Statistical Methods
  • Enzyme Catalysis and Immobilization
  • Natural Antidiabetic Agents Studies
  • Heat Transfer and Optimization
  • Studies on Chitinases and Chitosanases
  • Antioxidant Activity and Oxidative Stress
  • Chemical synthesis and pharmacological studies
  • Nanofluid Flow and Heat Transfer
  • Seed and Plant Biochemistry
  • Neuroscience and Neuropharmacology Research
  • Meat and Animal Product Quality
  • biodegradable polymer synthesis and properties

Nitte University
2024

University of Hyderabad
2023

University of Virginia
2023

Indian Institute of Integrative Medicine
2023

Academy of Scientific and Innovative Research
2023

National Institute of Animal Biotechnology
2023

Banaras Hindu University
2022

Jaipur National University
2018

Siksha O Anusandhan University
2012-2016

CSIR National Physical Laboratory of India
2013

Food oral processing is a study of mastication that involves food-saliva interaction. Instrumental approaches have improved sensorial attributes like texture by stimulating the environment for past years. However, thorough estimation food still an open research topic with persisting challenges. This review summarizes role tribology as novel tool sensory evaluation foods. The paper further covered state art on instrumentation, working principles, efficiency tribometer, and its application in...

10.1016/j.lwt.2022.113270 article EN cc-by-nc-nd LWT 2022-02-26

Abstract Polymethyl methacrylate ( PMMA ) nanofiber membrane NFM was synthesized by an electrospinning technique. These membranes were utilized as a support for immobilization of xylanase enzyme to study its p H stability, thermal and reusability. The morphology aligned studied optical microscopy scanning electron microscopy. functionalized with phenylenediamine activated glutaraldehyde yield aldehyde group on surface covalent xylanase. Fourier transform infrared analysis the covalently...

10.1002/bab.1072 article EN Biotechnology and Applied Biochemistry 2013-03-01

Cyclooxygenase (COX), is an enzyme that responsible for the formation of prostanoids, including thromboxane and prostaglandins. Prostaglandins promote inflammation. Blockage COX enzymes reduces prostaglandins thus their effects are reduced. The present study focuses on In silico ADMET, molecular docking studies binding energy calculations ten pyrimidine derivatives as cox-1 cox-2 inhibitors. Molecular were conducted two target enzymes. Energy minimisation ligands was carried out using...

10.5958/0974-360x.2020.00742.8 article EN Research Journal of Pharmacy and Technology 2020-01-01

In an effort to etablish new candidates with improved antineoplastic activity, 4-cycloalkylidineamino 1,2-naphthoquinone semicarbazones were synthesized, characterized and evaluated for anticancer activity. The desired compounds synthesized by condensation of 4- amino1, 2-naphthoquinone cyclic ketones further subsequent reaction this product semicarbazide hydrochloride. Compounds FT-IR, 1H NMR, 13C elemental analysis screened antiproliferative activity against three human cancer cell lines...

10.1016/s2221-1691(12)60358-x article EN Asian Pacific Journal of Tropical Biomedicine 2012-02-01

In an attempt to develop potent anticancer agents, a series of 4-arylideneamino/cycloalkylidineamino-1, 2-naphthoquinone thiosemicarbazones were synthesized and characterized using FT-IR, 1H NMR, 13C NMR spectroscopy elemental analysis. The compounds screened for antiproliferative activity against three human cancer cell lines (Hep-G2, MG-63 MCF-7) the MTT assay. Significant was observed several members series. 4-(3, 4, 5-trimethoxybenzylidene amino) 1, 2-naphthoquinone-2-thiosemicarbazone...

10.3109/14756366.2012.721783 article EN Journal of Enzyme Inhibition and Medicinal Chemistry 2012-09-14

The present work deals with the development of controlled release tablets salbutamol sulphate (SS) using graft copolymers methyl methacrylate (St-g-PMMA and Ast-g-PMMA) on starch acetylated starch. Formulations were evaluated for physical characteristics like hardness, friability, drug release, content weight variations, which fulfilled all official requirements tablet dosage form. rates from formulated matrix studied at SGF (pH 1.2) followed by SIF 6.8). Drug copolymer based was found to be...

10.1016/j.ajps.2014.12.003 article EN cc-by-nc-nd Asian Journal of Pharmaceutical Sciences 2014-12-22

Epilepsy is a long-lasting condition of the nervous system that impacts around 50 million individuals across globe. The defined by repeated episodes seizures, which can result in bodily harm, cognitive deficits, and emotional discomfort. Despite advances understanding treatment epilepsy, it remains significant health burden globally. Currently, management epilepsy involves use antiepileptic drugs (AEDs), surgery, lifestyle modifications. However, AEDs may cause side effects, some people with...

10.52711/0974-360x.2024.00335 article EN Research Journal of Pharmacy and Technology 2024-05-15
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