- Advanced Surface Polishing Techniques
- Advanced machining processes and optimization
- Additive Manufacturing Materials and Processes
- Advanced Machining and Optimization Techniques
- Nanoparticle-Based Drug Delivery
- Manufacturing Process and Optimization
- Soft Robotics and Applications
- Hydrogels: synthesis, properties, applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Nanoplatforms for cancer theranostics
- Lung Cancer Research Studies
- Diabetes Treatment and Management
- Antibiotics Pharmacokinetics and Efficacy
- Synthesis of β-Lactam Compounds
- Diatoms and Algae Research
- Pharmaceutical Economics and Policy
- Technology Assessment and Management
- High Entropy Alloys Studies
- Data Management and Algorithms
- Gastrointestinal Bleeding Diagnosis and Treatment
- Laser Material Processing Techniques
- Robot Manipulation and Learning
- Multiferroics and related materials
- Cancer therapeutics and mechanisms
- Robotic Path Planning Algorithms
Shenyang Ligong University
2015-2024
Xiangtan University
2020
China Pharmaceutical University
2012-2016
Chinese Academy of Sciences
2008
Shenyang Institute of Automation
2008
Abstract Objectives The clinical application of doxorubicin (DOX) is limited by severe systemic side effects. aim this study was to develop a strategy that combined the liposomal DOX (LipDOX) and intratumoral injection reduce toxicity enhance antitumor efficiency. Methods pharmacokinetics, tissue distribution pharmacodynamics LipDOX compared with free were investigated in murine H22 hepatoma-bearing mice at dose 20 mg/kg body weight. A sensitive HPLC-tandem mass spectrometry method used...
UGV (Unmanned Ground Vehicle) have many potential applications in a variety of areas. Path tracking is crucial issue for and one the most popular methods path PPA (Pure Pursuit Algorithm). Most researches using only consider look-ahead distance as constant parameter or function. Whereas fact, affected by some elements it would directly influence effect tracking. In this paper, an adaptive method based on proposed, which selected range value comparing error between planned actual path. This...
Gallium ferrite (GaFeO3) is a promising multiferroic material for multifunctional device applications. Compared with bulk and thin film materials, nanofibers are possible to magnify the magnetostriction or piezoelectric effect due their large length–diameter ratio, thus improving performance of material. In this work, GaxFe2 – xO3 (GFO) have been synthesized by sol-gel based electrospinning. With increasing Fe ion content, room-temperature antiferromagnetic ferromagnetic transition GFO has...
Analyzed the ultimate reason of over-cladding and under-cladding through combining with existing parallel scanning mode for laser metal deposition shaping (LMDS). A kind path generating algorithm is presented, firstly, adaptive scan space based on recognizing characteristic edge adopted to generate filling line; then, group optimize connect lines judging distance between end point last vector start next vector; finally, in every continuous subarea, corresponding speed according space, which...
1. MXN-004 is a water-soluble PEGylated 7-ethyl-10-hydroxy-camptothecin (SN38). The aim of this study was to evaluate the in vitro cytotoxicity and investigate pharmacokinetics tissue distribution its active metabolite SN38 rats. 2. In tested A549, HepG2 Caco-2 cancer cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay compared with irinotecan. MXN-004, irinotecan their identical were investigated after intravenous administration at same dose level 16...
Due to the high incidence of biliary and pancreatic diseases, ERCP (Endoscopic Retrograde Cholangio-Pancreatography) is widely used as an effective method for treating diseases. However, location diseases special, currently surgical instruments are not flexible enough make intubation process difficult cause damage human tissues. This paper presents a new type coaxial catheter intervention robot, which composed mechanical arm, driving mechanism, guide wire conveying mechanism. The robot...
Objective To determine a uitable sample pretreatment method in determination of arsenic urine and abest analysis condition the instrument. Methods Twenty copies morning samples health adults were collected; three methods wet digestion, constant temperature digestion microwave used to deal with eachurine sample. A certain concentration nitric acid solution as carrier,thiourea + L-ascorbic pre-reducing agent, potassium hydroxide borohydride reducing content was determined by atomic...
Abstract In order to achieve automatic rounding for blade tip, the study was conducted on small radius based elastic grinding, and a method of robot grinding fillets tip proposed.The wheel with polyester ammonia fiber as substrate material is utilized characteristics envelope deformation contact grind sharp angles fillets. Based theory Preston equation, theoretical model removal between were established. Abaqus software used simulate analyze stress distribution amount. Simulation result...