A5083240741- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Bone and Dental Protein Studies
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Reproductive biology and impacts on aquatic species
- Periodontal Regeneration and Treatments
- Forensic Anthropology and Bioarchaeology Studies
- Hormonal and reproductive studies
- Ovarian function and disorders
- Forensic and Genetic Research
- Historical Studies of Medieval Iberia
- Animal Genetics and Reproduction
- Selenium in Biological Systems
- Meat and Animal Product Quality
- Comparative constitutional jurisprudence studies
- Historical Art and Architecture Studies
- Animal Behavior and Welfare Studies
- Archaeology and ancient environmental studies
- Medieval Architecture and Archaeology
- Hypothalamic control of reproductive hormones
- Archaeological and Historical Studies
- dental development and anomalies
- Pharmacological Effects and Assays
- Genetics and Physical Performance
Autonomous University of Tlaxcala
2005-2024
Universidad Nacional Autónoma de México
2009-2024
Institute for Social Security and Services for State Workers
2023
Autonomous University of Tamaulipas
2014-2023
Centro Medico Nacional Siglo XXI
2023
Universidad de Los Andes
2023
National Archaeological Museum of Spain
2017-2021
Cambridge University Press
2021
New York University Press
2021
Institute of Entomology
2021
The emerging Bronze Age (BA) of southeastern Iberia saw marked social changes. Late Copper (CA) settlements were abandoned in favor hilltop sites, and collective graves largely replaced by single or double burials with often distinctive grave goods indirectly reflecting a hierarchical organization, as exemplified the BA El Argar group. We explored this transition from genomic viewpoint tripling amount data available for period. Concomitant rise starting ~2200 cal BCE, we observe complete...
The lysosomal response of a murine macrophage-like tumor cell line (J774) during persistent infection with Coxiella burnettii was examined. By using acid phosphatase as marker, it shown that phagosome-lysosome fusion occurred in J774 cells persistently infected C. burnetii. This observation verified thorium dioxide, an electron-dense compound is sequestered secondary lysosomes. phagolysosomes contained viable replicating rickettsiae. Spectrofluorometric analysis indicated the phagolysosomal...
Stress is associated with detrimental effects on male reproductive function. It known that stress increases reactive oxygen species (ROS) generation in the tract. High ROS levels may be linked to low sperm quality and infertility. However, it still not clear if are generated by testis. The objective of this study was characterize role oxidative induced cold-water immersion testis adult rats its relation alterations cauda epididymal sperm. Adult were exposed acute or chronic immersion. Rats...
Abstract Agriculture first reached the Iberian Peninsula around 5700 BCE. However, little is known about genetic structure and changes of prehistoric populations in different geographic areas Iberia. In our study, we focus on maternal makeup Neolithic (~ 5500–3000 BCE), Chalcolithic 3000–2200 BCE) Early Bronze Age 2200–1500 BCE). We report ancient mitochondrial DNA results 213 individuals (151 HVS-I sequences) from northeast, central, southeast southwest regions thus largest archaeogenetic...
We previously reported that amelogenin isoforms M180 and leucine-rich peptide (LRAP) are expressed in the periodontal region, their absence is associated with increased cementum defects amelogenin-knockout (KO) mice. The aim of present study was to characterize functions these osteoclastogenesis proliferation migration cementoblast/periodontal ligament cells. co-cultures wild-type (WT) osteoclast progenitor KO cells displayed more tartrate-resistant acid phosphatase (TRAP)-positive than WT...
The abundant amelogenin proteins are responsible for generating proper enamel thickness and structure, most amelogenins include a conserved hydrophilic C-terminus. To evaluate the importance of C-terminus, we generated transgenic mice that express an lacking C-terminal 13 amino acids (CTRNC). MicroCT analysis TgCTRNC29 teeth (low transgene number) indicated molar density was similar to wild-type mice, but TgCTRNC18 (high deficient, indicating extra copies were associated with more severe...
Testicular apoptosis is activated by stress, but it not clear which signaling pathway in response to stress. The aim of this study was investigate whether intrinsic, extrinsic, or both apoptotic pathways are acute and chronic Adult male rats were subjected cold water immersion-induced stress for 1, 20, 40, 50 consecutive days. seminiferous tubules:apoptotic cell ratio assayed on (1 day) (20, days) Apoptotic markers, including cleaved-caspase 3 8, the pro-apoptotic Bax anti-apoptotic Bcl-2...
Amelogenin proteins are secreted by ameloblasts within the enamel organ during tooth development. To better understand function of 180-amino-acid amelogenin (M180), and to test hypothesis that a single proline-to-threonine (P70T) change would lead an defect similar amelogenesis imperfecta (AI) in humans, we generated transgenic mice with expression M180, or M180 mutation, under control Amelx gene regulatory regions. teeth had relatively normal phenotype; however, P70T mineral was abnormally...
Introducción y objetivos El embarazo adolescente es un problema de salud pública mundial. En Chile no se ha estudiado su asociación a desigualdad determinantes sociales. Se evaluó la distribución del adolescente, cuantificó analizaron los factores socioeconómicos, demográficos sistema municipal asociados, por comunas chilenas.
The stimulatory and inhibitory role of serotonin in gonadotropin secretion the onset puberty male rat has been previously described, but its establishment spermatogenesis is not known. aim this study was to investigate effects serotoninergic inhibition by p-chloroamphetamine (pCA) on prepubertal-to-adult stage reproductive system. Hypothalamic serotonin, gonadotropins sex steroid hormone concentrations were measured, a histopathological analysis seminiferous epithelium carried out animals...
Here we show the effects of repeated electroejaculation (EE) on mean values motility, mitochondrial functionality, and expression active caspases goat sperm obtained by EE. Evaluations were done using CASA flow cytometry. A strategy for identification kinematic subpopulations, when individual data are not provided system, is provided. Fifty semen samples, five each ten adult creole goats, electroejaculation. Mean total progressive motility cytometry evaluations compared among EEs....
Abstract Serotonin [5‐hydroxytryptamine (5‐HT)] modulates ovarian function. The precursor of 5‐HT, 5‐hydroxytryptophan (5‐HTP), has been used to treat depression. However, the effects 5‐HTP on and reproductive physiology remain unknown. In this research, we analysed impact monoaminergic system its interactions with axis estradiol secretion when administered by distinct routes. Female rats 30 days age were injected i.p . (100 mg/kg), into bursa (1.5 µg/40 µL) or median raphe nucleus (20...
El dimorfismo sexual es una característica extendida en lacertilios y se relaciona con la adecuación de los individuos.En este estudio analizó si Aspidoscelis costata (Squamata) presenta al sur del Estado México, especialmente relación a su forma corporal altamente conservada dentro familia Teiidae.La población estudiada habita 1500 msnm.Se utilizaron individuos adultos que fueron capturados liberados durante estudios ecológicos.Para cada individuo registró longitud hocico-cloaca, el peso...
ABSTRACT: Swim‐up (SU) is a technique that permits the obtaining of motile sperm. Based on sperm motility neat ejaculates, we analyzed functional parameters, cytoplasmic esterases, and mitochondrial dehydrogenases ram using calcein acetomethylester resazurin, respectively. Active caspase‐3 −7 chromatin structure were evaluated in before after SU process. There no changes any viability parameters semen samples with less or more than 25% motility. The percentage active decreased (68.8 ± 4.6 vs...
Fluoxetine (Flx) is a selective serotonin reuptake inhibitor that alters the male reproductive system when administered at adult stage or after maternal exposure. In present study we evaluated effects of Flx administration on parameters during juvenile-peripubertal development treated rats reached adulthood. Groups were daily with (5mgkg-1, i.p.) saline (0.9% NaCl), left untreated. Rats between 30 and 53 days age killed 65 age. Serotonin concentrations determined in hypothalamus, hypophysis...
Spermatogenesis and steroidogenesis are testicular functions regulated by gonadotrophins as well other factors, including serotonin. Testicular serotonin acts an autocrine regulator of testosterone secretion, but studies on its role in spermatogenesis sperm quality scarce. Here, we analyzed the effects intratesticular inhibition synthesis gonadotrophins, testosterone, quality. Both testicles 30-day-old rats were injected once with saline solution (SS) or distinct concentrations...
Male germ-cell apoptosis occurs naturally and can be increased by exposure to drugs toxic chemicals. Individuals may have different rates of are likely also exhibit differential sensitivity outside influences. Previously, we reported that p-chloroamphetamine (pCA), a substance inhibits serotonin synthesis, induced in prepubertal male rats. Here, identified rats with high or low evaluated gene expression both groups. Bax Shbg mRNA levels were higher apoptosis. Rats then treated pCA the...
In order to identify unreliable data in a dataset of motility parameters obtained from pilot study acquired by veterinarian with experience boar semen handling, but without the operation computer assisted sperm analysis (CASA) system, multivariate graphical and statistical was performed. Sixteen samples were aliquoted then incubated varying concentrations progesterone 0 3.33 µg/ml analyzed CASA system. After standardization data, Chernoff faces pictured for each measurement, principal...