Abstract Aims: Baculoviral inhibitor of apoptosis repeat containing 5 (BIRC5) plays vital roles in carcinogenesis by influencing cell division and proliferation inhibiting apoptosis. However, the prognostic significance BIRC5 remains unclear breast cancer. Methods: expression methylation status were evaluated using Oncomine The Cancer Genome Atlas (TCGA) databases. relevance between different clinicopathological features as well survival information was analyzed bc-GenExMiner database...

Catheter ablation for atrial fibrillation (AF) has become a widely accepted procedure in most of the large cardiac centers throughout world. However, little is known regarding knowledge, attitude, and behavior (KAB) AF patients undergoing radiofrequency catheter (RFCA). Our purpose to investigate status influencing factors KAB these patients. We conducted survey utilizing specifically designed questionnaires among hospitalized RFCA from July 2008 April 2009. A total 116 participants were...

Abstract Background Mitochondrial permeability transition (MPT)-driven necrosis (MPTDN) is a non-apoptotic mode of cell death triggered by oxidative stress and cytosolic Ca 2+ overload. Recent evidence suggests that activation MPTND can effectively induce cancer may represent novel therapeutic strategy for cancer. Yet, the role MPTDN-related genes in non-small lung (NSCLC) remains unrevealed. This study aimed to identify biomarkers predicting prognosis guiding treatment NSCLC. Methods Gene...

To assess the psychometric properties of simplified Chinese version Nonrestorative Sleep Scale (NRSS) in young adults and examine measurement invariance across language age. After cognitive debriefing, NRSS was administered to university students mainland China this cross-sectional survey (Study 1). The Pittsburgh Quality Index (PSQI), Patient Health Questionnaire (PHQ-4), sociodemographic characteristics were also self-reported. sample randomly split into two halves scale structure using...

With the accelerated progress of global trade integration and profound transformation port shipping industry, collaborative development clusters has become an irreversible trend. This paper first analyzes necessity promoting from perspectives adapting to trend international enhancing regional competitiveness. Secondly, it elaborates on challenges faced by clusters, such as need for further clarification function positioning strengthening information sharing. Finally, puts forward targeted...

Stigma is assumed to lead negative illness identity in one who got chronic illness, and there a lack of understanding regarding the underly mechanisms. However, no research has examined extent which stigma was associated with people IBD. Therefore, we investigated relationship between identity, specifically examine whether resilience mediated or moderated relationship.

Aims. To verify the correlation between anorectal function and psychological conditions of depression/anxiety in patients with functional constipation. The aim this study is to explore why people have higher incidence constipation recommend innovative interventions advance patient care Design. A prospective correlational design. Methods. Anorectal manometry was performed on ( n = 70) through Medtronic Synectics PC Polygraf, while condition tested by Self‐Rating Anxiety Scale Depression...

This study aimed to understand the resilience experiences in patients with inflammatory bowel disease (IBD) and develop framework for them. Semistructured interviews were conducted 15 IBD who purposefully recruited from gastroenterology department of two hospitals Jiangsu, China gain diversity demographic clinical characteristics. The data analyzed using a directed content analysis approach based on Kumpfer's framework. was formed analysis. composed four themes, as follows: (1) complicated...

zhu f.‐f, lin z., l. & wang m.‐f. (2011) Changes in quality of life during biofeedback for people with puborectalis dyssynergia: generic and disease‐specific measures. Journal Advanced Nursing 67 (6), 1285–1293. Abstract Aim. The aim the study was to evaluate changes symptoms dyssynergia after by using Short Form‐36 Patient Assessment Constipation Quality Life Questionnaire. Background. Biofeedback is an effective treatment clinical dyssynergia. However, little known about degree...

To investigate the knowledge sharing behaviour of critical care nurse specialists and identify potential influencing factors.The specialist nurses is an important resource for nursing team. It necessary to factors them.Convenience sampling was used conduct investigation involving from three provinces in China between October 2018 June 2019. Practice Environment Scale, Competency Inventory Registered Nurses, Knowledge Self-efficacy scale were utilized.The score 64.84 ± 11.53. The results...

Abstract Background Breast cancer (BCa) is a major challenge for women’s health worldwide. Ferroptosis closely related to tumorigenesis and progression. However, the prognostic value of ferroptosis-related genes in BCa remains unclear, more accurate models are urgently needed. Methods Gene expression profiles clinical information patients were collected from public databases. LASSO multivariate Cox regression analysis utilized construct gene signature. Kaplan–Meier plotter, receiver...

Aim This study examined the effects of group psychological counselling on transition shock in newly graduated nurses. Background Newly nurses are often faced with as they enter workforce. Helping them adapt to new work environment and role quickly possible is an important goal for nursing managers. Method prospective, parallel-group, quasi-experimental trial enrolled 71 who were randomly assigned intervention (n = 38) or control 41) group. In addition routine hospital training, received...

e12500 Background: Anthracycline is widely used in breast cancer (BCa) chemotherapy, but acquired drug resistance remains a challenge. Increasing evidence suggests that changes the tumour immune microenvironment (TIME) consistently contribute to development of chemoresistance. Methods: TIME scores and tumor-infiltrating cells (TICs) were investigate prognosis, characteristics gene transcriptomic profiling HER2-negative BCa patients who received anthracycline chemotherapy. Exosomes from...

To investigate the emergency response capabilities of cardiovascular surgical nurses, analyze their correlation with self-efficacy and coping styles, summarize targeted intervention measures.

This study aims to explore the effect of Internet + E-Coach chronic disease system intervention on fasting blood glucose (FPG), 2-hour postprandial glucose(2hPG), serum insulin (FINS), triglyceride (TG), alanine transaminase (ALT) and quality life in patients with diabetic retinopathy. 208 retinopathy who were treated hospital from March 2021 2023 are chosen separated into two groups by random number Table 104 control group received routine continuous intervention, research intervention. The...

BACKGROUND:Rifaximin is an antimicrobial agent used to treat inflammatory bowel disease (IBD). Vitamin D3 can control IBD due its effects on cytokines. The purpose of this study was assess the effect vitamin intestinal flora a dextran sulfate sodium (DSS)-induced mouse model treated with rifaximin. MATERIAL AND METHODS:The developed using DSS (4%) administered via drinking water. Twenty-four male C57BL6 mice were divided into group normal diet (N=6), rifaximin and (N=6). After 14 days,...