- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Respiratory and Cough-Related Research
- Phonocardiography and Auscultation Techniques
- Orthopedic Surgery and Rehabilitation
- Noise Effects and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Elbow and Forearm Trauma Treatment
- Cystic Fibrosis Research Advances
- Infant Health and Development
- Child and Adolescent Psychosocial and Emotional Development
- Dupuytren's Contracture and Treatments
- Peripheral Nerve Disorders
- Child Nutrition and Feeding Issues
- Mobile Health and mHealth Applications
- Pediatric health and respiratory diseases
- Myasthenia Gravis and Thymoma
- Perfectionism, Procrastination, Anxiety Studies
- Pharmaceutical studies and practices
- Voice and Speech Disorders
Vitalograph (Ireland)
2014-2024
Trinity College Dublin
2014-2019
Jefferson Healthcare
1977
St. Johns Hospital
1977
Albyn Hospital
1977
St John's Hospital
1977
In severe asthma, poor control could reflect issues of medication adherence or inhaler technique, that the condition is refractory. This study aimed to determine if an intervention with (bio)feedback on features use would identify refractory asthma and enhance technique adherence.Patients uncontrolled were subjected a stratified-by-site random block design. The intensive education group received repeated training in use, disease management. same intervention, enhanced by (bio)feedback-guided...
Rationale Poor adherence to inhaler use can be due poor temporal and/or technique adherence. Up until now there has been no way of reliably tracking both these factors in everyday use. Objectives This paper introduces a device developed create time stamped acoustic recordings an individual's use, which empirical evidence and monitored over time. The correlation between clinical outcomes adherence, as determined by this device, was compared for alone combined Findings technology validated...
Many patients make critical user technique errors when using pressurised metered dose inhalers (pMDIs) which reduce the clinical efficacy of respiratory medication. Such include poor actuation coordination (poor timing medication release during inhalation) and inhaling too fast (peak inspiratory flow rate over 90 L/min). Here, we present a novel audio-based method that objectively assesses patient pMDI technique. The Inhaler Compliance Assessment device was employed to record inhaler audio...
Poor adherence to inhaled medication may lead inadequate symptom control in patients with respiratory disease. In practice it can be difficult identify poor adherence. We designed an acoustic recording device, the INCA® (INhaler Compliance Assessment) which, when attached inhaler, identifies and records time technique of inhaler use, thereby providing objective longitudinal data on individual's medication. This study will test hypothesis that objective, personalised, visual feedback...
Asthma and chronic obstructive pulmonary disease (COPD) patients are required to inhale forcefully deeply receive medication when using a dry powder inhaler (DPI). There is clinical need objectively monitor the inhalation flow profile of DPIs in order remotely patient technique. Audio-based methods have been previously employed accurately estimate parameters such as peak inspiratory rate inhalations, however, these multiple calibration audio recordings. In this study, an audio-based method...
Introduction In clinical practice, it is difficult to distinguish between patients with refractory asthma from those poorly controlled asthma, where symptoms persist due poor adherence, inadequate inhaler technique or comorbid diseases. We designed an audio recording device which, when attached inhaler, objectively identifies the time and of use, thereby assessing both aspects adherence. This study will test hypothesis that feedback on these two adherence passed improves helps clinicians...
The efficacy of drug delivery from inhalers is very much dependent on the user's peak inspiratory flow rate (PIFR). Current methods to measure PIFR in are based subjective checklists. There a lack currently available objectively remotely monitor pressurized metered dose (pMDIs) and dry powder (DPIs). In this study, for first time, non-contact acoustic were employed estimate through three commonly used (Diskus™ DPI, Turbuhaler™ Evohaler™ pMDI) with aim applying these inhaler inhalation...
Chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) affect over 400 million people are incurable. The pressurized metered dose inhaler (pMDI) has been the most popular device in inhaled therapy recent times. However pMDIs require good coordination between inhaling actuating to deliver aerosolized drug effectively. Poor can greatly reduce amount of delivered a patient therefore reducing control symptoms. Acoustic methods have recently employed monitor...
This Letter investigated the efficacy of a decision-support system, designed for respiratory medicine, at predicting asthma exacerbations in multi-site longitudinal randomised control trial. Adherence to inhaler medication was acquired over 3 months from patients with employing dose counter and remote monitoring adherence device which recorded participant's use: n = 184 (23,656 audio files), 61% women, age (mean ± sd) 49.3 16.4. Data on occurrence collected three clinical visits, 1 month...
Inhalers are hand-held devices used to treat chronic respiratory diseases such as asthma and obstructive pulmonary disease (COPD). Medication is delivered from an inhaler the user through inhalation maneuver. It unclear whether gender anthropometric features age, height, weight body mass index (BMI) influence acoustic properties of inspiratory sounds peak flow rate (PIFR) in inhalers. In this study, healthy male (n=9) female (n=7) participants were asked inhale at (IFR) 60 L/min four...
The dose delivery from dry powder inhalers is dependent on user inhalation technique, particularly the peak inspiratory flow rate (PIFR). Non-contact acoustic methods have recently been employed to objectively measure PIFR during inhaler use. This study aimed further acoustics research by extracting features sounds using non-contact and tracheal microphones correlating these with PIFR. also investigated repeatability of position peaks troughs power spectral density (PSD) profile across...
Asthma is a chronic respiratory disease affecting millions of people worldwide, and consequently major issue for global health. Exacerbations are acute events involving the worsening asthma's primary symptoms cause morbidity in asthma patients, largely due to unpredictability their onset. This study aimed investigate relationship between changes acoustic features inhaler inhalations forced expiratory volume one second (FEV1) that occur during simulated exacerbation, bronchial challenge test...
Audio analysis of cough sounds can provide objective measures respiratory clinical features such as frequency. Audio-based 24-hour ambulatory monitoring systems currently lead the way in providing these across a range diseases. However, to preserve data privacy audio recordings, there is interest remove any identifiable information contained within patient and third-party speech. In this study we employed real-life recordings from VitaloJAK device. We developed an audio-based speech...
Chronic respiratory diseases may be controlled through the delivery of medication to airways and lungs using an inhaler. However, adherence correct inhaler technique is poor, which impedes patients from receiving maximum clinical benefit their medication. In this study, Inhaler Compliance Assessment device was employed record audio a Diskus dry powder An algorithm that classifies sounds (blister, inhalation, interference) developed automatically assess patient these recordings. The presented...
Synopsis A survey of more than 6000 school children in 1961 established norms for symptomatology and behaviour at ages 5–15. follow-up to 1968 identified all from the attending a child guidance clinic or appearing court within that time. Those thus contained significantly high proportion boys who were reported as having 3 deviant items (i.e. occurring approximately 10% subjects 1961). Specific health behavioural found have been proportions which different later those court. The amount...
<h3>Background</h3> Severe asthma can be due difficult to treat poor adherence or refractory asthma. Identifying challenging since the methods of have limitations. We developed a method assessing using Inhaler compliance assessment (INCA) device, which incorporates both identifying technique errors and time use inhaler. hypothesised that feedback on patients, improves adherence, compared standard education without visual feedback. <h3>Methods</h3> This was 3-month prospective multicentre...