- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Pneumothorax, Barotrauma, Emphysema
- COVID-19 and healthcare impacts
- Pleural and Pulmonary Diseases
- Diagnosis and treatment of tuberculosis
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular and Diving-Related Complications
- Tuberculosis Research and Epidemiology
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Diphtheria, Corynebacterium, and Tetanus
- Pharmacological Effects of Natural Compounds
- Mycobacterium research and diagnosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Trauma Management and Diagnosis
- Family and Patient Care in Intensive Care Units
- Plant-based Medicinal Research
- Immune Cell Function and Interaction
- Neuroscience of respiration and sleep
- IL-33, ST2, and ILC Pathways
Ospedale Monaldi
2019-2024
Ospedale D. Cotugno
2020-2021
Federico II University Hospital
2019-2020
Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli
2019
Università a Vicenza
2019
University of Naples Federico II
2018
We describe a 42-year old woman, admitted to our Department after 15 days of persistence respiratory failure and treated with infusion intravenous immunoglobulin successful outcome.
Background: Pneumomediastinum, subcutaneous emphysema and pneumothorax are not rarely observed during the COVID-19 pandemic. Such complications can worsen gas exchange overall prognosis in critical patients. The aim of this study is to investigate what predisposing factors related pneumomediastinum SARS-CoV2-Acute Respiratory Distress Syndrome (ARDS), symptoms may predict a severe potentially fatal complication therapeutical approach provide better outcome. Methods: In single center cohort...
Aims To estimate if chronic anticoagulant (CAC) treatment is associated with morbidity and mortality outcomes of patients hospitalized for SARS-CoV-2 infection. Methods In this European multicentric cohort study, we included 1186 whom 144 were on CAC (12.1%) positive coronavirus disease 2019 testing between 1 February 30 July 2020. The average effect (ATE) analysis a propensity score-matching (PSM) algorithm was used to the impact primary defined as in-hospital death, major minor bleeding...
Abstract Background Hypoxia affects myocardial oxygen supply resulting in subclinical cardiac dysfunction obstructive sleep apnea (OSA) patients, with cardiovascular complications being associated increased oxidative burst (OB). The aims of our study were to assess left ventricular (LV) dynamic deformation and diastolic reserve at rest upon exercise, along OB determination this patients subset. Methods Conventional echocardiography, Doppler imaging LV 2D speckle tracking echocardiography...
A high-flow nasal cannula (HFNC) is an alternative device for oxygena-tion, which improves gas exchange and reduces the work of breathing. Postextubation respiratory failure causes increased morbidity mortality. HFNC has been widely employed during COVID-19 pandemic. The purpose this paper to report a single-centre experience on effectiveness safety in weaning patients.Nine patients showed severe acute interstitial pneumonia due SARS-CoV-2. After mechanical ventilation (5 Helmet CPAP, 4...
There is evidence that hypopneas are more common than apneas in obstructive sleep apnea (OSA) related to idiopathic pulmonary fibrosis (IPF). We investigated the frequency distribution of 100 patients with interstitial lung diseases (ILDs) (mean age 69 yrs ± 7.8; 70% males), including 54 IPF cases, screened for OSA by home testing. Fifty age- and sex-matched pure were included as controls. In ILD-OSA breathing pattern was characterized a high prevalence preceded hyperpnea events configuring...
Prostate cancer is the most common non-cutaneous malignancy diagnosed in men. It usually metastasizes to bone as osteoblastic lesions on radiographs and regional lymph nodes, uncommonly lung, liver brain. Metastatic prostate recurrence after definitive local therapy can occur any tissue. The role of fine needle aspiration cytology (FNAC) for diagnosis metastatic malignancies well established literature. We describe a 74 years old male, previously treated localized cancer, admitted our...
The coronavirus disease 2019 (COVID-19) is a recent pandemic that affected more than 5 million people worldwide. Chest high resolution computed tomography (HRCT) an essential tool in diagnosis and management of the disease. Pulmonary parenchymal opacity typical sign disease, but not only one. Pneumothorax, pneumomediastinum, bronchiectasis cysts are probably underrated complications COVID-19 can worsen prognosis, terms prolonged hospitalization need oxygen therapy. In our single center case...
Objective: The aim of our study was to assess the effect a short-term treatment with low-moderate corticosteroid (CS) doses by both quantitative and qualitative assessment chest HRCT COVID-19 pneumonia. Methods: CORTICOVID is single-center, cross-sectional, retrospective involving severe/critical patients mild/moderate ARDS. Lung total severity score obtained according Chung colleagues. Moreover, relative percentages lung ground glass opacities, consolidations, crazy paving, linear bands...
BACKGROUND: High flow nasal cannula (HFNC) showed better oxygenation than standard oxygen therapy delivered through a face mask in acute respiratory failure for all causes. HFNC may offer an alternative patients with hypoxemia and potentially reduce mortality. It was widely applied China during the COVID-19 emergency. However, no data have been published about settings protocols. The purpose of this paper to report single center experience on effectiveness safety weaning associated...
Infection with severe acute respiratory syndrome coronavirus 2 causes disease 2019 (COVID-19) which was revealed an official pandemic by the World Health Organization on 11 March 2020. The current pandemic, third of this decade, is worst in terms suffering and deaths related. COVID-19 represents unprecedented challenge for medical communities patients around world. High-resolution computed tomography chest (HRCT) a fundamental tool both management diagnosis disease. Imaging plays essential...
The coronavirus disease 2019 (COVID-19) pneumonia was a recent worldwide outbreak. During chest computed tomography (CT) we may observe pulmonary parenchymal opacity, as sign of COVID-19. Very few have reported pneumothorax and pneumomediastinum complications severe COVID-19 pneumonia. We describe 44-year-old male admitted to our department after the onset sudden pain high fever evidence on spontaneous pneumomediastinum, subsequently confirming
Hospital overcrowding, driven by both structural management challenges and widespread medical emergencies, has prompted extensive research into machine learning (ML) solutions for predicting patient length of stay (LOS) to optimize bed allocation. While many existing models simplify the LOS prediction problem a classification task, broad ranges hospital days, an exact day-based regression model is often crucial precise planning. Additionally, available data are typically limited...
The World Health Organization declared the Coronavirus Diseases 2019 (COVID-19) outbreak a global pandemic on March 11, 2020. COVID-19 had an impact over 500 million people worldwide. According to American Thoracic Society criteria, respiratory spectrum of this disease ranges from mild illness severe pneumonia, with latter occurring in not insignificant 15% patients. A rapid increase incidence pneumonia cases has been observed all world, resulting saturation Intensive Care Unit's capacity...
In conclusion, we believe that patients with COVID-19 pneumonia acute hypoxemic respiratory failure should be treated PEEP.CPAP is the non-invasive treatment of choice, and appropriate choice interface could improve tolerance outcomes in patients.