A5047076982- Smoking Behavior and Cessation
- Carcinogens and Genotoxicity Assessment
- Indoor Air Quality and Microbial Exposure
- Global Public Health Policies and Epidemiology
- Systemic Lupus Erythematosus Research
- Air Quality and Health Impacts
- Nicotinic Acetylcholine Receptors Study
- Microfinance and Financial Inclusion
- Heavy Metal Exposure and Toxicity
- Community Development and Social Impact
- Systemic Sclerosis and Related Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Genetically Modified Organisms Research
- Financial Literacy, Pension, Retirement Analysis
- Atherosclerosis and Cardiovascular Diseases
- T-cell and B-cell Immunology
- Health Systems, Economic Evaluations, Quality of Life
- Fatty Acid Research and Health
- Cardiovascular Health and Risk Factors
- COVID-19 Clinical Research Studies
- Cytokine Signaling Pathways and Interactions
- Toxic Organic Pollutants Impact
- Genomics, phytochemicals, and oxidative stress
- Effects and risks of endocrine disrupting chemicals
- Rheumatoid Arthritis Research and Therapies
Grigore T. Popa University of Medicine and Pharmacy
2021-2025
Clinical Emergency Hospital Bucharest
2021-2025
Centers for Disease Control and Prevention
2014-2024
Center for Global Health
2020-2024
Abdelmalek Essaâdi University
2023
Centers for Disease Control and Prevention
2022
United States Food and Drug Administration
2014-2021
RTI International
2011-2021
National Center for Environmental Health
2011-2017
Office of the Chief Scientist
2017
Context.—Cotinine, a metabolite of nicotine, is marker exposure to tobacco smoke. Previous studies suggest that non-Hispanic blacks have higher levels serum cotinine than whites who report similar cigarette smoking.Objective.—To investigate differences in black, white, and Mexican American smokers the US adult population.Design.—Third National Health Nutrition Examination Survey, 1988-1991.Participants.—A nationally representative sample persons aged 17 years or older participated...
Approximately one-fourth of all cigarettes sold in the United States are mentholated. An understanding consequences, patterns, and correlates menthol cigarette use can guide development implementation strategies to reduce smoking prevalence smoking-attributable morbidity mortality. This paper summarizes literature on health effects mentholated describes various patterns as indicated by consumption survey data from other nations. The epidemiological cancer risk is inconclusive regarding...
Objective Oral tobacco products contain nicotine and carcinogenic tobacco-specific N -nitrosamines (TSNAs) that can be absorbed through the oral mucosa. The aim of this study was to determine typical pH ranges concentrations total nicotine, unionised (the most readily form) five TSNAs in selected distributed globally. Methods A 53 from 5 World Health Organisation (WHO) regions were analysed for TSNAs, including 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), using gas chromatography...
Background Access to medicines is important for long-term care of cardiovascular diseases and hypertension. This study provides a cross-country assessment availability, prices, affordability disease hypertension identify areas improvement in access medication treatment. Methods Results We used the World Health Organization online repository national essential lists (EMLs) 53 countries transcribe information on inclusion 12 disease/hypertension medications within each country's list. Data...
We assessed 12 urine metals in tobacco smoke-exposed and not exposed National Health Nutrition Examination Survey participants. Our analysis included age, race/ethnicity, poverty status. Gender racial/ethnic differences cadmium lead creatinine-adjusted unadjusted data for group comparisons are presented. Smokers’ had higher cadmium, lead, antimony, barium levels than nonsmokers. Highest were the youngest subjects. Lead among adults with high second-hand smoke exposure equaled smokers. Older...
In 2005, approximately 2.3% of U.S. adults used smokeless tobacco. Moist snuff leads all types tobacco in revenues and marketing expenditures. The Surgeon General has concluded that use can lead to nicotine addiction. National Toxicology Program the Institutes Health classified as a human carcinogen. Tobacco-specific nitrosamines (TSNAs) are potent carcinogens products, pH product influences content un-ionized which is form most rapidly absorbed mouth. Centers for Disease Control Prevention...
The cadmium (Cd) present in air pollutants and cigarette smoke has the potential of causing multiple adverse health outcomes involving damage to pulmonary cardiovascular tissue. Injury epithelium may include alterations tight junction (TJ) integrity, resulting impaired epithelial barrier function enhanced penetration chemicals biomolecules. Herein, we investigated mechanisms involved disruption TJ integrity by Cd exposure using an vitro human air-liquid-interface (ALI) airway tissue model...
To provide researchers an extensive characterization of the SPECTRUM variable nicotine research cigarettes.Data on cigarette physical properties, content, harmful and potentially constituents in tobacco filler was compiled.Data concentrations menthol, minor alkaloids, tobacco-specific nitrosamines, polycyclic aromatic hydrocarbons, ammonia, toxic metals for all available varieties Spectrum cigarettes are provided. The similarity chemistry properties to commercial renders them acceptable use...
Rheumatoid arthritis (RA) is a chronic autoimmune condition frequently found in rheumatological patients that sometimes raises diagnosis and management problems. The pathogenesis of the disease complex involves activation many cells intracellular signaling pathways, ultimately leading to innate acquired immune system producing extensive tissue damage. Along with joint involvement, RA can have numerous extra-articular manifestations (EAMs), among which lung damage, especially interstitial...
Objective: Survey of nicotine, tar, and carbon monoxide (CO) smoke deliveries from 77 cigarette brands purchased in 35 countries was conducted using a standardised machine smoking method. The goal this study to determine regional variations differences the CO yields brand manufactured by leading transnational corporation non-US locally popular brands. Design: majority cigarettes were each participating delegate members World Health Organization forwarded Centers for Disease Control...
The Escherichia coli somatic pilus, 987P, has been purified after removal by homogenization from a 987P+ enterotoxigenic E. coli. Cell-free pili were precipitated the addition of MgCl2, collected, and dissolved in MgCl2-free buffer. Five cycles precipitation dissolving resulted preparation 987P that was judged to be homogeneous based on electron microscopy sodium dodecyl sulfate-polyacrylamide gel electrophoresis. In microscope, rod shaped, having diameter 7 nm an apparent axial hole. Cells...
This study examines child poisonings resulting from ingestion of tobacco products throughout the nation and assesses potential toxicity novel smokeless products, which are concern with their discreet form, candy-like appearance, added flavorings that may be attractive to young children.Data representing all single-substance, accidental by children <6 years age, reported poison control centers, were examined. Age association versus other was tested through logistic regression. Total nicotine...
Tobacco smoke is a source of exposure to thousands toxic chemicals including lead, chemical longstanding public health concern. We assessed trends in blood lead levels youths and adults with cotinine-verified tobacco by using 10 years data from the National Health Nutrition Examination Survey.Geometric mean are presented for increasing exposure. Regression models included age, race/ethnicity, poverty, survey year, sex, age home, birth country, and, adults, alcohol consumption. Lead were...
We revisited the association between progress in MPOWER implementation from 2008 to 2016 and smoking prevalence 2009 2017 offered an in-depth understanding of differential outcomes for various country groups.We used data six rounds WHO Reports on Global Tobacco Epidemic calculated a composite Score each period. categorised countries four initial conditions based their tobacco control preparedness measured by score burden age-adjusted adult daily 2006: (1) High - high (HM-HP). (2) low...
Journal Article Surveillance of smokeless tobacco nicotine, pH, moisture, and unprotonated nicotine content Get access Patricia Richter, Ph.D., Ph.D. Office Smoking Health Correspondence: A. M.P.H., D.A.B.T., Centers for Disease Control Prevention, on Health, 4770 Buford Highway, N.E., MS K-50, Atlanta, GA 30341, USA. Tel: + 1 (770) 488-5825; Fax: 488-5848; E-mail: pir1@cdc.gov Search other works by this author on: Oxford Academic PubMed Google Scholar Francis W. Spierto, National Center...