Katherine Afton

ORCID: 0000-0003-2379-5945
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Adolescent and Pediatric Healthcare
  • Cardiovascular Issues in Pregnancy
  • Cardiac Structural Anomalies and Repair
  • Childhood Cancer Survivors' Quality of Life
  • Coronary Artery Anomalies
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Conditions and Treatments
  • Non-Invasive Vital Sign Monitoring
  • Congenital heart defects research
  • Surgical Simulation and Training
  • Cardiovascular Function and Risk Factors
  • Anatomy and Medical Technology
  • Congenital Anomalies and Fetal Surgery
  • Vascular anomalies and interventions
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Simulation-Based Education in Healthcare
  • Total Knee Arthroplasty Outcomes
  • Cardiac Arrhythmias and Treatments
  • Congenital Diaphragmatic Hernia Studies

University of Michigan
2015-2024

Michigan United
2024

C. S. Mott Children's Hospital
2015-2022

Michigan Medicine
2022

RELX Group (United States)
2019

In the SVR trial (Single Ventricle Reconstruction), newborns with hypoplastic left heart syndrome were randomly assigned to receive a modified Blalock-Taussig-Thomas shunt (mBTTS) or right ventricle-to-pulmonary artery (RVPAS) at Norwood operation. Transplant-free survival was superior in RVPAS group 1 year, but no longer differed by treatment 6 years; both groups had accumulated important morbidities. third follow-up of this cohort (SVRIII [Long-Term Outcomes Children With Hypoplastic Left...

10.1161/circulationaha.123.065192 article EN cc-by-nc-nd Circulation 2023-10-05

Virtual reality has emerged as a unique educational modality for medical trainees. However, incorporation of virtual curricula into formal training programmes been limited. We describe multi-centre effort to develop, implement, and evaluate the efficacy curriculum residents participating in paediatric cardiology rotations.A software program ("The Stanford Heart") was utilised. Users are placed "inside heart" explore non-traditional views cardiac anatomy. Modules six common congenital heart...

10.1017/s1047951122000890 article EN Cardiology in the Young 2022-04-25

Abstract Background: Amongst patients with CHD, the time of transition to adulthood is associated lapses in care leading significant morbidity. The purpose this study was identify differences perceptions between parents and teens regard readiness. Methods: Responses were collected from 175 teen–parent pairs via validated CHD Transition Readiness survey an information request checklist. distributed electronic tablet at a routine clinic visit. Results: Parents reported perceived knowledge gap...

10.1017/s1047951120004813 article EN Cardiology in the Young 2021-01-11

Objective: Transition is defined as “the process by which adolescents and young adults with chronic childhood illnesses are prepared to take charge of their lives health in adulthood”. We previously reported common knowledge deficits lack transition readiness (TR) 13-25 year olds congenital or acquired heart disease. The aims this study were re-evaluate TR these patients at follow-up (F/U) examine the relationship between changes quality life (QOL). Methods: Patients (n=106) completed...

10.1161/circ.130.suppl_2.12926 article EN Circulation 2014-11-25

Pulmonary arterial hypertension (PAH) is a complex disease involving increased resistance in the pulmonary arteries and subsequent right ventricular (RV) remodeling. Ventricular-arterial interactions are fundamental to PAH pathophysiology but rarely captured computational models. It important identify metrics that capture quantify these inform our understanding of this as well potentially facilitate patient stratification. Towards end, we developed calibrated two multi-scale high-resolution...

10.3389/fphys.2022.958734 article EN cc-by Frontiers in Physiology 2022-09-07

Introduction: Increased knowledge of quality life (QOL) and the potential impact Fontan on QOL is essential to improving outcomes in patients with single ventricle. The primary aim Pediatric Heart Network Single Ventricle Reconstruction (SVR) trial II was investigate subjects SV at age 6 yrs while SVR III characterized this cohort 10-12 yrs. Aims: purpose study evaluate changes health-related from identify factors associated over time. Methods: Parents completed proxy-reports for their child...

10.1161/circ.150.suppl_1.4122307 article EN Circulation 2024-11-11

Introduction: Limited data exist on the electrophysiologic outcomes of patients undergoing anatomic repair (AR) for congenitally corrected transposition great arteries (ccTGA). AR was defined as an atrial switch procedure plus either arterial (ASO) or Rastelli operation. Aims: To report mid and late after identify risk factors those outcomes. Methods: Single center retrospective cohort study between 1993-2017. Data were collected from available records. Transplant-free survival to 1 year...

10.1161/circ.142.suppl_3.14198 article EN Circulation 2020-11-12

Introduction: The SVR Trial demonstrated that the right ventricle-to-pulmonary artery shunt (RVPAS) vs. modified Blalock-Taussig-Thomas (MBTTS) at Norwood operation was associated with better early survival for children hypoplastic left heart syndrome (HLHS). However, it remains unclear if type is cardiac function, morbidities or in older children. Methods: survivors were followed annually. Cardiac MRI and cycle ergometry performed 10-12 years (y) of age III participants. Outcomes compared...

10.1161/circ.144.suppl_1.10502 article EN Circulation 2021-11-16

Introduction: Transition is defined as “the process by which adolescents and young adults with chronic childhood illnesses are prepared to take charge of their lives health in adulthood”. Knowledge deficits lack transition readiness (TR) 13-25 year olds congenital or acquired heart disease have been previously reported. The aim this multicenter study was examine agreement between parental perceptions adolescent’s TR (knowledge, self-efficacy, self-management behaviors) adolescent...

10.1161/circ.134.suppl_1.13080 article EN Circulation 2016-11-11

Abstract Background: Neurocognitive impairment and quality of life are two important long-term challenges for patients with complex CHD. The impact re-interventions during adolescence young adulthood on neurocognition is not well understood. Methods: In this prospective longitudinal multi-institutional study, 13–30 years old severe CHD referred surgical or transcatheter pulmonary valve replacement were enrolled. Clinical characteristics collected, executive function assessed prior to the...

10.1017/s1047951123003979 article EN cc-by Cardiology in the Young 2023-11-30

Introduction: After anatomic repair (AR) of congenitally corrected transposition the great arteries (ccTGA), left ventricle (LV) is re-established as systemic ventricle. As such, LV dysfunction an important factor in long-term patient morbidity. While predictors exist for successful AR, little known regarding measures function before and after no worsening global longitudinal strain (GLS). Methods: All patients with ccTGA who survived to discharge AR at a single institution from 2000-2018...

10.1161/circ.142.suppl_3.16631 article EN Circulation 2020-11-17

Introduction: Children with complex congenital heart disease (CHD) are at increased risk for neurodevelopmental impairments and reduced quality of life (QOL). Patients (pts) congenitally corrected transposition the great arteries (ccTGA) often undergo anatomic repair to make left ventricle systemic ventricle, goal long term cardiac benefits. Understanding long-term outcomes QOL may inform preoperative counseling treatment strategies ccTGA. Methods: We measured using PedsQL generic modules...

10.1161/circ.142.suppl_3.15375 article EN Circulation 2020-11-17

Introduction: Anatomic repair of congenitally corrected transposition the great arteries (ccTGA) generally poses short-term risk for presumed long-term functional benefit by restoring left ventricle to systemic circulation. Understanding early and late surgical outcomes is crucial counseling patients families. Methods: All with anatomic at a single institution from 1993-2018 were included. Follow-up data was obtained contact patients’ primary cardiologists. The outcome survival secondary...

10.1161/circ.142.suppl_3.15704 article EN Circulation 2020-11-17
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