A5101763715- Hormonal Regulation and Hypertension
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Injury Epidemiology and Prevention
- Telomeres, Telomerase, and Senescence
- Urban Green Space and Health
- Land Use and Ecosystem Services
- Healthcare Systems and Public Health
- Estrogen and related hormone effects
- Hormonal and reproductive studies
- Pharmacological Effects and Assays
- Cardiovascular Health and Risk Factors
- Trauma and Emergency Care Studies
- Organ Transplantation Techniques and Outcomes
- Circadian rhythm and melatonin
- Traffic and Road Safety
- Healthcare and Venom Research
- Sulfur Compounds in Biology
- Environmental Education and Sustainability
- Neuroblastoma Research and Treatments
- Health and Wellbeing Research
- Plant Diversity and Evolution
- Climate Change and Health Impacts
Hebei University
2025
Beijing Center for Disease Prevention and Control
2024
Xuchang University
2024
Tohoku University
2019-2022
First Hospital of Jilin University
2021
Jilin University
2021
Chinese Center For Disease Control and Prevention
2016-2021
National Center for Chronic and Noncommunicable Disease Control and Prevention
2015-2019
Fudan University
2012
Guangzhou University of Chinese Medicine
2010
BackgroundA comprehensive evaluation of the burden injury is an important foundation for selecting and formulating strategies prevention. We present results from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2017 non-fatal fatal outcomes at national subnational level, changes in key causes over time China.MethodsUsing methods GBD 2017, we describe total based on rates incidence, cause-specific mortality, disability-adjusted life years (DALYs) China estimated using DisMod-MR 2.1....
Regular visits to park green space offer remarkable benefits for the physical and mental health of urban residents. Achieving a comprehensive understanding utilization across entire city is prerequisite improving overall rate spaces. Traditional social survey methods are limited by their sample size time-consuming nature, while based on geographic location big data gaining momentum. This study focuses Xuchang, medium-sized in China, systematically analyzes current state influencing factors...
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Pheochromocytomas (PHEOs) are relatively rare catecholamine-producing tumors derived from adrenal medulla. Tumor microenvironment (TME) including neoangiogenesis have been explored in many human neoplasms but not necessarily PHEOs. Therefore, this study, we firstly examined tumor infiltrating lymphocytes (CD4 and CD8), associated macrophages (CD68 CD163), sustentacular cells (S100p) angiogenic markers (CD31 areas of intratumoral hemorrhage) 39 cases PHEOs the quantitative fashion. We then...
Aldosterone plays pivotal roles in renin-angiotensin-aldosterone system order to maintain the equilibrium of liquid volume and electrolyte metabolism. action is mediated by both mineralocorticoid receptor 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Its excessive actions directly induced tissue injuries its target organs such as myocardial vascular fibrosis addition chronic kidney diseases. Excessive aldosterone were also reported be involved unbalanced metabolism inflammatory bowel...
Abstract p16 is generally considered to be a surrogate maker of human papillomavirus (HPV) infection and also predictive marker favorable clinical outcome patients with squamous cell carcinoma the oropharynx. overexpression known induced by deregulation RB1 in neuroendocrine carcinomas. In highly malignant esophageal neoplasms, however, status has remained largely unknown. We immunolocalized Rb1 82 surgically resected high-grade carcinomas (46 poorly differentiated 36 basaloid carcinomas) 15...
Primary aldosteronism (PA) is the most common cause of secondary hypertension, and associated with an increased incidence cardiovascular events. PA itself clinically classified into following two types: unilateral PA, mostly composed aldosterone-producing adenoma (APA); bilateral hyperaldosteronism, consisting multiple micronodules (APMs) diffuse hyperplasia. Histopathologically, those disorders above are all compact clear cells. The cellular morphology in above-mentioned has been recently...
Abstract Context Although numerous theories are reported on sex differences in longevity, the underlying biological mechanisms remain unknown. We previously that telomere length zona reticularis cells of human adrenal cortex was significantly longer older than younger subjects. However, we could not evaluate lengths. Objective To compare lengths adrenocortical and medullar between men women from infancy through adulthood. Methods Adrenal glands 30 male (aged 0 to 100 years) 25 female 104...
Cortisol-producing adenoma (CPA) is composed of clear and compact cells. Clear cells are lipid abundant, ones poor but associated with higher production steroid hormones. PRKACA mutation (PRKACA mt) in CPA patients was reported to be more pronounced clinical manifestation Cushing’s syndrome. In this study, we examined the association histological features genotypes cholesterol uptake receptors synthetic enzymes 40 cases, quantitative results obtained by gas chromatography-mass spectrometry...
In situ cortisol excess was previously reported to promote cellular senescence, a cell response stress, in cortisol-producing adenomas (CPA). The aim of this study explore senescence pathways aldosterone-producing cells and related disorders, the influence aldosterone overproduction on senescence. We analyzed 30 surgical cases adenoma (APA), 10 idiopathic hyperaldosteronism (IHA) 19 normal adrenals (NA). CYP11B2 markers p16 p21 were immunolocalized all those above results correlated with...
The study focused on individuals with influenza-like symptoms (fever, cough, sore throat, runny nose, and other respiratory symptoms) in three kindergartens Tongzhou District, Beijing City, April 2023. Nasopharyngeal swab specimens were collected, real-time fluorescent quantitative PCR was used to detect common pathogens the collected specimens. Positive subjected sequencing analysis of highly variable region human syncytial virus (HRSV) G protein, homology phylogenetic tree analysis. A...
This study develops a methodological framework for measuring energy conservation and CO2 emission reductions that considers both origins destinations. The encompasses four key aspects: transportation, accommodation, cooking, housing rehabilitation. Data were collected through literature review, questionnaire surveys, field measurement tracking. Compared to living in the origin, senior tourists from Nanchang visiting Zhongyuan Township China summer tourism can save 5.747 MJ of reduce...