A5050732346- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Physiological and biochemical adaptations
- Reproductive biology and impacts on aquatic species
- MicroRNA in disease regulation
- Animal Genetics and Reproduction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Circular RNAs in diseases
- Peroxisome Proliferator-Activated Receptors
- Wind and Air Flow Studies
- Industrial Vision Systems and Defect Detection
- Adipose Tissue and Metabolism
- Fish Ecology and Management Studies
- Antioxidant Activity and Oxidative Stress
- Identification and Quantification in Food
- Building Energy and Comfort Optimization
- Muscle Physiology and Disorders
- Image Processing Techniques and Applications
- RNA modifications and cancer
- Urban Heat Island Mitigation
- Respiratory Support and Mechanisms
- Lipid metabolism and biosynthesis
- Fish Biology and Ecology Studies
Chinese Academy of Fishery Sciences
2016-2025
Beijing United Family Hospital
2025
Ministry of Agriculture and Rural Affairs
2021-2025
Pennsylvania State University
2023-2025
Beijing Forestry University
2013-2025
Nanjing Agricultural University
2016-2024
Johns Hopkins University
2024
Institute of Atmospheric Physics
2020-2024
Chinese Academy of Sciences
2017-2024
Anhui Jianzhu University
2024
Sustainable development of the largemouth bass industry is hindered by limited freshwater resources. Consequently, expansion farming space brackish and saline water aquaculture has become imperative. Largemouth an economically important fish species. However, there presently a lack germplasm resources with capacity to adapt hypertonic environments maintain rapid growth. A genome-wide association study technique used for detection genetic variants associated specific phenotypic traits. In...
To combat the spread of antibiotic resistance, methods that quantitatively assess metabolism-inhibiting effects drugs in a rapid and culture-independent manner are urgently needed. Here using four oral bacteria as models, we show heavy water (D2O)-based single-cell Raman microspectroscopy (D2O-Raman) can probe bacterial response to different shift at C–D (carbon–deuterium vibration) band 2040 2300 cm–1 universal biomarker for metabolic activity single-bacterial-cell resolution. The "minimum...
The interactions between microorganisms driven by substrate metabolism and energy flow are important to shape diversity, abundance, structure of a microbial community. Single cell technologies useful tools for dissecting the functions individual members their in communities. Here, we developed novel Raman stable isotope probing (Raman-SIP), which uses microspectroscopy coupled with reverse D2O colabeling study metabolic two-species community consisting Acinetobacter baylyi ADP1 Escherichia...
Tilapia tolerate hypoxia; thus, they are an excellent model for the study of hypoxic adaptation. In this study, we determined effect acute hypoxia stress on antioxidant capacity, metabolism, and gill/liver ultrastructure male genetically improved farmed tilapia (GIFT, Oreochromis niloticus). Fish were kept under control (dissolved oxygen (DO): 6.5 mg/L) or (DO: 1.0 conditions 72 h. After 2 h stress, enzyme activities in heart gills decreased, while malondialdehyde (MDA) content increased....
Abstract Background Dissolved oxygen (DO) in the water is a vital abiotic factor aquatic animal farming. A hypoxic environment affects growth, metabolism, and immune system of fish. Glycolipid metabolism energy pathway under acute stress, it plays significant role adaptation fish to stressful environments. In this study, we used multi-omics integrative analyses explore mechanisms hypoxia Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus ). Results The 96 h median lethal (96...
Elucidation of the molecular mechanisms governing aggressiveness HNSCC may provide clinical therapeutic strategies for patients. In this study, a novel hub miR-204-5p functioning as tumor suppressor has been identified and explored in HNSCC. Methods: A was based on miRNA microarray, bioinformatics analysis validated different patient cohorts. The functional role its downstream upstream regulatory machinery were investigated by gain-of-function loss-of-function assays vitro vivo. Interactions...
Transport is essential in cross-regional culturing of juvenile fish. Largemouth bass (Micropterus salmoides) often exhibit decreased vitality and are susceptible to disease after transportation. To study the effects transport stress on largemouth bass, juveniles (average length: 8.42 ± 0.44 cm, average weight 10.26 0.32 g) were subjected a 12 h simulated transport, then subsequently, allowed recover for 5 d. Liver intestinal tissues collected at 0, 6 d recovery. Oxidative immunological...
Tilapia is susceptible to hepatic steatosis when grown in intensive farming systems. The aim of this study was explore the mechanism fatty liver induced by a high-fat diet (HFD) genetically improved farmed tilapia (GIFT, Oreochromis niloticus). Juvenile GIFT were fed with HFD or normal-fat (NFD) for 60 days. Substantial fat deposition HFD-fed on days 20, 40, and observed using hematoxylin - eosin staining oil red O staining. increased consistent triglyceride (TG) total cholesterol (TC)...
Aquaculture feed containing olive oil (OO) instead of fish (FO) can cause oxidative stress and impair gonad development in fish. We determined the effect dietary OO-induced on ovarian development, explored whether vitamin E (VE) could mitigate negative effects. Female Nile tilapia (Oreochromis niloticus) were fed for 10 weeks with four diets: 5% OO + 70 mg/kg VE, 200 FO or VE. Dietary reduced specific growth rate gonadosomatic index, inhibited superoxide dismutase catalase, delayed decreased...
The present study was performed to investigate the effects of dietary lipid level on growth performance, antioxidant defense, and mRNA levels digestive enzymes immune genes in larval genetically improved farmed tilapia (Oreochromis niloticus). results show that larvae fed 4–11.5% had greater weight gain (WG), feed efficiency, protein efficiency ratio survival than other (P < 0.05). No difference whole-body crude protein, ash or moisture contents were found between treatments > 0.05) but...
The aim of this study was to determine the effects different dietary protein levels on growth, physiological parameters, and gut microbiome genetically improved farmed tilapia (GIFT, Oreochromis niloticus). Two pellet feed diets with low (25%, LPD) normal (35%, NPD) were fed GIFT in aquaria at 28°C for 8 weeks. LPD reduced trypsin activity inhibited growth GIFT. serum alanine amino transferase aspartate transaminase activities, hepatic malondialdehyde content, superoxide dismutase,...
The largemouth bass (Micropterus salmoides) has become an important freshwater fish in China since it was intentionally introduced the 1980 s, and amount produced aquaculture is increasing each year. Females are preferred because they grow faster than males reach a larger body size. However, physiological sex cannot be accurately determined from external morphology at early growth stage, so crucial to develop sex-specific molecular markers. In this study, single nucleotide polymorphism (SNP)...