A5100336600- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Plant Stress Responses and Tolerance
- Plant tissue culture and regeneration
- Genetic Mapping and Diversity in Plants and Animals
- Plant Surface Properties and Treatments
- Plant Reproductive Biology
- Inflammatory Bowel Disease
- Microscopic Colitis
- Animal Genetics and Reproduction
- Photosynthetic Processes and Mechanisms
- Plant Genetic and Mutation Studies
- Chromosomal and Genetic Variations
- Biochemical and Molecular Research
- Autoimmune and Inflammatory Disorders
- Legume Nitrogen Fixing Symbiosis
- Silicon Effects in Agriculture
- Hemodynamic Monitoring and Therapy
- Diet and metabolism studies
- Fluid Dynamics and Heat Transfer
- Sepsis Diagnosis and Treatment
- Polysaccharides and Plant Cell Walls
- Genomics, phytochemicals, and oxidative stress
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Peking Union Medical College Hospital
2021-2024
Southwest University
2023-2024
Lanzhou University
2021-2024
Capital Medical University
2024
Huazhong Agricultural University
2007-2024
Beijing Tian Tan Hospital
2024
Université de Bourgogne
2024
Centre National de la Recherche Scientifique
2024
Université de technologie de belfort-montbéliard
2024
Summary Grain weight is the most important component of rice yield and mainly determined by grain size, which generally controlled quantitative trait loci ( QTL s). Although numerous s that regulate have been identified, genetic network controls size remains unclear. Herein, we report cloning functional analysis a dominant , length width 2 GLW ), positively regulates simultaneously increasing width. The locus encodes OsGRF4 (growth‐regulating factor 4) regulated micro RNA miR396c in vivo ....
Background and Aims Itaconate, a metabolite of the tricarboxylic acid cycle, plays anti‐inflammatory roles in macrophages during endotoxemia. The mechanisms underlying its have been shown to be mediated by modulation oxidative stress, an important mechanism hepatic ischemia–reperfusion (I/R) injury. However, role itaconate liver I/R injury is unknown. Approach Results We found that deletion immune‐responsive gene 1 (IRG1), encoding for enzyme producing itaconate, exacerbated systemic...
Abstract Osmotic stress activates the biosynthesis of abscisic acid (ABA). One major step in ABA is carotenoid cleavage catalyzed by a 9-cis epoxycarotenoid dioxygenase (NCED). To understand mechanism for osmotic activation biosynthesis, we screened Arabidopsis thaliana mutants that failed to induce NCED3 gene expression response treatments. The ced1 (for defective 1) mutant isolated this study showed markedly reduced (polyethylene glycol) treatments compared with wild type. Other genes are...
Current research has shown that microRNAs (miRNAs) play vital roles in plant response to stress caused by heavy metals such as aluminum, arsenic, cadmium (Cd), and mercury. Cd become one of the most hazardous pollutants environment. Maize can be a potential model study phytoremediation Cd-contaminated soil owing its large biomass production. However, little is known about miRNAs maize. To investigate role stress, roots seedlings inbred maize lines B73 Mo17 were collected treated with 200...
Aberrant expression of microRNAs (miRNAs) has been implicated in cancer initiation and progression. In this study, we found that microRNA-34a (miR-34a) is significantly downregulated glioblastoma multiforme (GBM) specimens compared with normal brain tissues. Growth curve colony formation assays revealed miR-34a suppresses proliferation U373MG SHG44 cells. Overexpression could induce apoptosis Also, identified notch1 as a direct target gene miR-34a. Knockdown showed similar cellular functions...
The stress hyperglycemia ratio (SHR) was developed to reduce the effects of long-term chronic glycemic factors on levels, which associated with adverse clinical outcomes. This study aims evaluate relationship between postoperative SHR index and all-cause mortality in patients undergoing cardiac surgery. Data for this were extracted from Medical Information Mart Intensive Care IV (MIMIC-IV) database. Patients categorized into four groups based quartiles. primary outcome 30-day mortality,...
Purpose.: We investigated the potential of human parthenogenetic embryonic stem cells (hPESCs) to differentiate into RPE cells, and identified development-regulating microRNAs (miRNAs). Methods.: were derived from hPESCs. The expression markers miRNA profiles during differentiation studied by immunocytochemistry, real-time RT-PCR, array at three time points. Human fetal (hfRPE) also analyzed. target genes candidate miRNAs then validated. Results.: hPESC-derived exhibited similar morphology...
Stearoyl lysophosphatidylcholine (LPC) exerts protective effect during endotoxemia and in experimental sepsis, but the underlying mechanism is unclear. Here, we demonstrated that stearoyl LPC could block caspase-11-mediated macrophage pyroptosis. In vitro, significantly decreased caspase-11 activation pyroptosis induced by lipopolysaccharide (LPS) plus cholera toxin subunit B independent of receptor G2A. did not affect LPS uptake mouse peritoneal macrophages inhibit interaction between...
Quorum sensing plays a necessary role in the production of virulence factors and formation biofilm on Pseudomonas aeruginosa. Thus, development inhibition quorum is one most promising methods to control bacterial infection antibiotic resistance. In this work, nine novel AHL analogs were designed, synthesized, evaluated as potential inhibitors. The results depicted that structural modifications have significant effects activity molecules. Without inhibiting growth P. aeruginosa,...
Lycium barbarum has been used for more than 2500 years as a traditional herb and food in China. We investigated the effects of polysaccharides (LBP) on apoptosis, oxidative damage, expression adhesion molecules bone marrow mononuclear cells (BMNC) mice injured by ionizing radiation. Kunming were exposed to X-rays; then LBP groups continuously injected with various concentrations intraperitoneally 14 days. Mice control group normal saline (NS) same route A was set up. After 1, 7, days...
Abstract Olfaction plays key roles in insect survival and reproduction, such as feeding, courtship, mating, oviposition. The olfactory-based control strategies have been developed an important means for pest management. Streltzoviella insularis is a destructive of many street tree species, characterization its olfactory proteins could provide targets the disruption their odour recognition processes urban forestry protection. In this study, we assembled antennal transcriptome S. by...
Fragrance is one of the most important quality traits in rice, and phenotype attributed to loss-of-function betaine aldehyde dehydrogenase (BADH2) gene. At least 12 allelic variations BADH2 have been identified, some these applied rice fragrance breeding using traditional molecular markers Sanger sequencing techniques. However, methods several limitations, such as being very expensive, imprecise, inefficient, having security issues. Thus, a new marker technology must be developed improve...
Summary In the storage process, meat is susceptible to external factors that produce corruption and deterioration, affecting consumers' health. Therefore, preparing an indicator membrane can detect freshness in real time, non‐destructively, visually significant. Herein, was prepared by electrostatic spinning technology using polyvinyl alcohol (PVA) as substrate curcumin (CUR) indigo (IND) mixed for detection. When were at 3:1 (w/w), CUR transformed from ketone type enol with gradual increase...