A5049790374- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Adolescent and Pediatric Healthcare
- Intestinal Malrotation and Obstruction Disorders
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Childhood Cancer Survivors' Quality of Life
- Delphi Technique in Research
- Intestinal and Peritoneal Adhesions
- Electrolyte and hormonal disorders
- Infant Development and Preterm Care
- Renal Transplantation Outcomes and Treatments
- Nutrition and Health in Aging
- Renal Diseases and Glomerulopathies
- Antibiotics Pharmacokinetics and Efficacy
- Organ Transplantation Techniques and Outcomes
- Airway Management and Intubation Techniques
Emma Kinderziekenhuis
2019-2025
University of Amsterdam
2022-2025
Amsterdam University Medical Centers
2019-2025
Catheter-related thrombosis (CRT) is a serious complication associated with home parenteral nutrition (HPN) in children chronic intestinal failure (CIF). Guidelines on pediatric HPN state that there insufficient evidence to advocate the prophylactic use of CRT. Aim evaluate efficacy and safety anticoagulation preventing CRT HPN. We performed prospective, international, multicenter study across three expertise centers. Children aged 0-18 years were included divided into two groups: 1)...
Abstract Background and Aims Life expectancy for patients with chronic intestinal failure (CIF) recieving home parenteral nutrition (HPN) has improved over the past decades. Consequently, more children on HPN grow into adulthood. Until now, no assessment of transition readiness these exists. Aim is to assess adolescents HPN. Methods This an international, prospective, cross‐sectional multicenter study in collaboration members Intestinal Failure working group—European Reference Network Rare...
Abstract Background Children with chronic IF require long‐term home parenteral nutrition (HPN), administered through a central venous catheter. Catheter‐related bloodstream infection (CRBSI) Staphylococcus aureus is known to be serious high mortality rate and risk of complications. A standardized protocol on the management S CRBSIs in children receiving HPN lacking. The aim this study evaluate effectiveness safety current an expertise center Netherlands. Methods We performed retrospective...
Life expectancy of children with chronic intestinal failure (CIF) on home parenteral nutrition has greatly improved. Children are now able to grow into adulthood which requires transfer from pediatric adult health care. A guideline for structured transition is lacking and the demand a more standardized care this patient group necessary. Therefore, we investigated perceptions professionals various disciplines working in specific field, concerning effective interventions regarding
Objectives: The objective of this study is to assess the psychopathology and medical traumatic stress in children with intestinal failure (IF) identify associated risk factors. Methods: Two-center study, performed from September 2019 until April 2022 (partly during COVID-19 pandemic), including (1.5–17 years) IF, dependent on parenteral nutrition (PN) or weaned off PN, treated by a multidisciplinary IF-team. Psychopathology was evaluated semi-structured interview assessing psychiatric...
In research on pediatric chronic intestinal failure, heterogeneity in reported definitions and outcomes exists. This leads to a risk of reporting bias impossibility evidence synthesis. Also, should be relevant both healthcare providers patients their parents. Therefore, the aim this study is create core outcome set (COS) used studies failure.Candidate were selected from recent systematic review. A three-round Delphi among key stakeholders consensus meeting with an expert panel undertaken...
Abstract Objectives To describe incidence, clinical course, diagnostic and therapeutic management long‐term follow‐up of paediatric intestinal pseudo‐obstruction (PIPO) in the Netherlands between 2000 2020. Methods Multicenter, national, retrospective, observational study including patients aged <18 years diagnosed with PIPO treated 2020 Dutch academic medical centres. Outcomes included demographics, symptoms, diagnostic‐ treatment methods used during follow‐up, number hospital admissions...
Abstract The necessity of post‐transplant monitoring for donor‐specific antibodies (DSAs) is unclear. This study evaluates the clinical relevance post‐transplantation HLA in pediatric renal transplant recipients, aiming at better stratification patients risk graft dysfunction and recommendations monitoring. A cohort 68 kidney involving 76 transplantations between 2004 2014, was studied retrospectively. All were screened 1, 3, 6, 12 months after transplantation yearly thereafter. Samples...
Pediatric intestinal pseudo-obstruction (PIPO) management is based on nutritional, medical, and surgical care while available evidence scarce. The aim of this study was to outline the current diagnostic strategies in failure (IF) teams European Reference Network for rare Inherited Congenital Anomalies (ERNICA) compare these practices latest PIPO international guidelines. An online survey institutional conducted among ERNICA IF teams. In total, 11 21 centers from 8 countries participated. On...
Introduction: In research on pediatric chronic intestinal failure, heterogeneity in reported definitions and outcomes exists. This results reporting bias impossibility of evidence synthesis. Also, should be clinical relevant to both healthcare providers, parents patients this field. Therefore, the aim study is create a core outcome set for failure. standardized agreed upon by key stakeholders. Methods: Based data from recent systematic review, that almost hundred different measures are used...
Introduction: Catheter related blood stream infection (CRBSI) with Staphylococcus aureus is known to be a serious high mortality rate in adults and risk of infectious complications. Therefore, removal the catheter advised when S. detected. However, paucity data pediatric patients chronic intestinal failure (IF) receiving home parenteral nutrition (HPN) exists current management based on retrieved from adult patients. Especially this patient group, removing their lifeline not preferable due...
Introduction: Life expectancy of children with chronic intestinal failure has greatly improved. This is mainly due to improvement home parenteral nutrition (HPN) and prevention treatment its complications. Children are now able grow into adulthood which requires transfer from pediatric adult health care. However, a protocol for structured transition lacking. Therefore, as first step in developing protocol, we investigated the view care professionals various disciplines this field concerning...