Guillaume Vial
A5037348678- Otitis Media and Relapsing Polychondritis
- Systemic Lupus Erythematosus Research
- Diet and metabolism studies
- Peptidase Inhibition and Analysis
- Liver Disease Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Viral-associated cancers and disorders
- Microscopic Colitis
- Obstructive Sleep Apnea Research
- Chronic Lymphocytic Leukemia Research
- Vasculitis and related conditions
- Neuroscience of respiration and sleep
- Metabolism, Diabetes, and Cancer
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Laser Applications in Dentistry and Medicine
- Vascular Anomalies and Treatments
- Infective Endocarditis Diagnosis and Management
- Celiac Disease Research and Management
- Health and Medical Education
- Cancer, Hypoxia, and Metabolism
- COVID-19 Clinical Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Platelet Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Mitochondrial Function and Pathology
Hôpital Saint-André
2020-2025
Polyclinique Bordeaux Nord Aquitaine
2024
Université Grenoble Alpes
2009-2024
Inserm
2010-2024
Centre Hospitalier Universitaire de Grenoble
2018-2024
Centre Hospitalier Universitaire de Bordeaux
2021-2023
Hotel Dieu Hospital
2023
Polyclinique de Bordeaux-Tondu
2023
Université de Bordeaux
2020-2022
Bordeaux Population Health
2022
A new autoinflammatory syndrome related to somatic mutations of UBA1 was recently described and called VEXAS ('Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic syndrome').To describe clinical characteristics, laboratory findings outcomes syndrome.One hundred sixteen patients with were referred a French multicentre registry between November 2020 May 2021. The frequency median parameters vital status, from diagnosis the end follow-up, recorded.The main features found be skin lesions...
Sleep Apnea Syndrome (SAS) is one of the most common chronic diseases, affecting nearly billion people worldwide. The repetitive occurrence abnormal respiratory events generates cyclical desaturation-reoxygenation sequences known as intermittent hypoxia (IH). Among SAS metabolic sequelae, it has been established by experimental and clinical studies that an independent risk factor for development progression non-alcoholic fatty liver disease (NAFLD). principal goal this study was to decrypt...
Abstract Aim Obstructive sleep apnea (OSA) is a growing health problem affecting nearly 1 billion people worldwide. The landmark feature of OSA chronic intermittent hypoxia (CIH), accounting for multiple organ damage, including heart disease. CIH profoundly alters both visceral white adipose tissue (WAT) and structure function, but little known regarding inter‐organ interaction in the context CIH. We recently showed that WAT senescence drives myocardial alterations aged mice without Here, we...
The association of immune thrombocytopenia (ITP) with cancer has been reported, but the causality tumor cells in paraneoplastic ITP pathogenesis and maintenance never established. We analyzed unusual case refractory coincident urothelial kidney circulating high titer anti-GPIIBIIIA autoantibodies. Intriguingly, after nephrectomy, patient recovered fully her autoantibodies disappeared. Proteomic immunohistochemistry analyses revealed erratic GPIIB expression by cells, suggesting possible...
Objectives To assess the tolerance and efficacy of targeted therapies prescribed off-label in refractory low-prevalence autoimmune inflammatory systemic diseases. Methods The TATA registry (TArgeted Therapy Autoimmune Diseases) is a prospective, observational, national independent cohort follow-up. inclusion criteria are as follows: age >18 years; disease treated with drugs started after 1 January 2019. Results Hundred (100) patients (79 women) were enrolled. median was 52.5 years (95% CI...
This study evaluates the safety and potential benefits of PBM on pancreatic beta cells islets. was applied to insulin-secreting cell lines (MIN6) rat islets using a 670 nm light source, continuous output, with power density 2.8 mW/cm², from 5 s several 24 h. Measure viability, insulin secretion, mitochondrial function, ATP content, cellular respiration were assessed. Additionally, diabetic model is used for islet transplantation (pre-conditioning or not) experiments. Short long-term exposure...