Aluminium (Al) is the third most abundant element in earth's crust and its compounds are used form of house hold utensils, medicines antiperspirant etc. Increasing number evidences suggest involvement Al+3 ions a variety neurodegenerative disorders including Alzheimer's disease. Here, we have attempted to investigate role Al endoplasmic reticulum stress regulation p53 during neuronal apoptosis using neuroblastoma cell line. We observed that caused oxidative by increasing ROS production...

Suicide has been around for as long human society, ranking among the top 13 causes of death in all ages worldwide and continues to challenge our collective wisdom. The present study is a retrospective evaluating suicide cases Lucknow, capital Uttar Pradesh one largest cities India, between Jan 2008 Oct 2012. There were 5204 with 2946 male (56.61%) 2258 female (43.38%) victims, 20 60 years; rates ranged from 21.55 24.23 per 100,000 population. method was different victims tried use more...

Vinayan, Kollencheri Puthenveettil; Saini, Arushi Gahlot; Jyotsna, Aruna Setumadhava; Singh, Gagandeep; Aneja, Satinder; Jayalakshmi, Sita; Kanhere, Sujata; Sylaja, PN; Panigrahi, Debasis; Verma, Anoop Kumar Author Information

Abstract Background Accurate post-mortem interval (PMI) determination remains crucial in forensic investigations. Building on our previous findings of miRNA-378, miRNA-206, and miRNA-195 as potential PMI biomarkers, this study evaluates their efficacy burn electrocution cases. We incorporate cardiac troponin I (cTnI) to enhance estimation precision. This multi-biomarker approach aims elucidate the combined miRNA protein-based indicators for determinations across diverse causes mortality,...

Interstitial capillary congestion and diffuse alveolar damage (DAD) were frequently observed in patients who died from Coronavirus disease-19 (COVID-19). The research question pertains to observing these findings COVID-19-positive lacking pulmonary symptoms. histological examination of lung samples do not succumb COVID-19-related complications can provide an answer. This study analyzed postmortem autopsy individuals did complications. article aimed examine the morphological variations...

In our modern world, people from all walks of life and demographics agree that education is crucial. today's knowledge-driven society, everyone needs access to high-quality if they want thrive. The special educators benefitted the training received, which allowed them provide their low vision children with appropriate functional instruction. Utilizing Low Vision Devices for Scanning - Teachers have difficulties while trying scan poor equipment. Students' expectations are since vision....

Electrical burns are associated with significant morbidity and mortality, which usually preventable simple safety measures. An observational retrospective study of non-lightening electrocution deaths was conducted in Lucknow, India between 2008 2012. Out 83 deaths, 71 investigated were accidental the rest suicidal. The age range 11 months to 75 years a mean 28.9 ± 12.5 years. About 65 (78%) males females. upper extremity most frequently involved contact site 51 (61%). No electrical burn...

Abstract Estimation of time death is an indispensible requirement every medico‐legal autopsy, but unfortunately, there not a single method by which it could be determined accurately. This study focused on the temperature‐dependent postmortem degradation cardiac troponin‐T and its association with interval ( PMI ) in human. The analysis involved extraction protein, separation denaturing gel electrophoresis SDS ‐ PAGE ), visualization Western blot using cTnT ‐specific monoclonal antibodies....

Background: Aim of this trial was to evaluate the combined clinical and radiographic success rate endodontic treatment using passive ultrasonic irrigation (PUI) laser activated (LAI) as compared conventional syringe irrigation.Material Methods: Permanent incisors single rooted premolars were assessed for eligibility 69 patients randomly divided into three groups (n=23) by allocation concealment method performed in accordance with allocated group.Teeth evaluated clinically radiographically...

DNA technology has proved to be a worthy investigative tool for releasing the innocent citizens and bringing forth person responsible serious crimes. In populated country like India there is requirement these types of databases. The Union government working on new version legislation that seeks set up national database 'offenders'. As expected with great success use forensic databases, challenges are coming up. To rise challenges, different strategies have been proposed increasing search...

Lip prints, like fingerprints, are unique to an individual and can be easily recorded. Therefore, we compared direct indirect lip print patterns in males females of different age groups, studied the inter- intraobserver bias recording data, observed any changes over a period time, thereby, assessing reliability prints as forensic tool.Fifty 50 group 15 35 years were selected for study. Lips with deformity or scars not included. registered by methods transferred preformed registration sheet....

The purpose of this study was to assess vascularity the lunate by number foramina and radiography vessels wrist. genesis lunatomalacia requires some vascular risk mechanical predisposition. findings were correlated with cause Kienböck's disease. more than two in 91.33% lunate. had consistent dorsal palmar branches from radial artery. additional anterior interosseous artery 72.22% a branch inter carpal arch 69.44% cases contributed arterial anastomosis on aspect blood supply found 85.71%...

The age at which first menstrual bleeding occurs in female, i.e menarche is viewed as an excellent physiological marker of adolescent maturation. aim this study to determine the mean among girls and assess influence some Bio-social parameters affecting it. This was conducted 150 group 10 19 years, randomly selected from urban & rural government schools Lucknow. 75 each school were November 2009 March 2010. a cross sectional descriptive study. Girls studied about their socioeconomic status,...