A5077451473- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Gastrointestinal motility and disorders
- Organometallic Compounds Synthesis and Characterization
- Crystal structures of chemical compounds
- Crystallography and molecular interactions
- Gut microbiota and health
- Probiotics and Fermented Foods
- Lanthanide and Transition Metal Complexes
- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Complementary and Alternative Medicine Studies
- Congenital gastrointestinal and neural anomalies
- Organophosphorus compounds synthesis
- Therapeutic Uses of Natural Elements
- Food composition and properties
- Long-Term Effects of COVID-19
- Inflammatory Bowel Disease
- Pharmacological Effects of Natural Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Mindfulness and Compassion Interventions
- Child Nutrition and Feeding Issues
- Eosinophilic Esophagitis
- Adrenal Hormones and Disorders
Sechenov University
2019-2024
Taras Shevchenko National University of Kyiv
2002-2012
Background Irritable bowel syndrome (IBS) affects 9,2% of the global population and places a considerable burden on healthcare systems. Most medications for treating IBS, including spasmolytics, laxatives, antidiarrheals, have low efficacy. Effective safe therapeutic treatments yet to be developed IBS. Purpose This study assessed efficacy safety food supplement containing standardized menthol, limonene, gingerol in human participants with IBS or IBS/functional dyspepsia (FD). Design A...
Iron(III) coordination compounds of the general formula FeL 3 (where L 1 = {CCl C(O)NP(O)-[N(C 2 H 5 ) ] - }-N,N'-tetraethyl-N''-trichloroacetylphosphorictriamide anion, and C(O)NP(O)[N(CH CH O] } -dimorpholido-N-trichloroacetylphosphoricamide anion) have been synthesized characterized by means IR, UV-VIS, ESR spectroscopy, X-ray analysis. The complexes a molecular structure with phosphoryl ligands coordinated to metal ioninabidentatemanner via carbonyl oxygen atomswith formation six...
In the title compound, C(6)H(13)Cl(3)N(3)O(2)P or CCl(3)C(O)NHP(O)(N(CH(3))(2)), phosphinoyl group is synclinal to carbonyl and acts as an acceptor for inter-molecular N-H⋯O hydrogen bond from amide donor.
In the title diaqua-cobalt complex, [Co(C(8)H(11)NO(5)PS)(2)(H(2)O)(2)], Co(II) atom is surrounded by six O atoms belonging to phosphoryl and sulfonyl groups of two deprotonated chelate ligands additional from water mol-ecules which are in cis positions with respect one another. The coordination environment cobalt can be described as a distorted octa-hedron. O-H⋯O hydrogen bonds between neighboring form chains running parallel [010]. Two methoxy attached phosphorus disordered over sets sites...
Introduction. Genetic predisposition in combination with environmental factors and the patient’s psychological emotional state play a key role development of irritable bowel syndrome (IBS). Studies association between genetic polymorphisms IBS can help understanding pathophysiological mechanisms. To date, 11 meta-analyses on this issue have been published, however, none them comprehensively summarize data prevalence predominant constipation (IBS-C). Aim: to published impact risk IBS-C....
The crystal structure of the title calcium complex, [Ca(C(8)H(11)NO(5)PS)(2)](n), is composed a polymeric chain, which formed due to two bridging sulfonyl groups linking Ca(II) ions in O-S-O-Ca manner. Thus, coordination environment six O atoms belonging phosphoryl and chelate rings additional groups. polyhedron central atom (2 symmetry) has distorted octa-hedral geometry.
The title compound, C(4)H(12)N(+)·C(8)H(11)NO(5)PS(-), was obtained from tetra-methyl-ammonium hydroxide and dimeth-yl(phenyl-sulfon-yl)amido-phosphate. cation has a slightly distorted tetra-hedral configuration the N-C bond lengths lie in range 1.457 (3)-1.492 (3) Å. In crystal, no classical hydrogen bonds are observed between anion.
Aim: to demonstrate the clinical picture and tactics of differential diagnosis between ulcerative colitis Clostridium difficile -associated disease in a patient with APS-1, as well describe managing such patients. Key findings. A 25-year-old autoimmune polyglandular syndrome type 1 (APS-1) complained loose stools up 10 times day blood admixture, rapidly growing weakness weight loss 5 kg per week. When examined on admission, surgical pathology was excluded. Further diagnostics carried out,...
Aim: to demonstrate the management of a patient with somatization disorder and irritable bowel syndrome. Key points. A 41-yo female was admitted complains spastic lower abdomen pain, hard stool once every 1–2 days under laxative treatment (macrogol), bloating, anxiety, waiting for confirmation life threatening illness, internal stress, difficulty in falling asleep, shallow sleep. Has long history disease, characterized by appearance variety somatic symptoms (headache, tachycardia, joint...
Aim : to study the effectiveness and safety of using drug Kolofort® in outpatients with irritable bowel syndrome (IBS) after a new coronavirus infection. Materials methods . An observational non-interventional program was conducted patients exacerbation IBS symptoms One hundred forty-one took part study. The final efficacy analysis included data from 127 participants. All complained increased/appearing gastrointestinal that appeared within 1–6 months infection (all had history COVID-19...
Aim: evaluation of the effectiveness nutraceutical “Standard Zdorovia: Gastro” (“SZ Gastro”) in treatment patients with irritable bowel syndrome (IBS). Materials and methods. 52 (62 % women) diagnosed IBS combination functional dyspepsia (FD) were included study divided into two groups. Both groups received basic therapy according to guidelines. The experimental group as add-on “SZ (containing a standardized amount menthol, gingerol D-limonene); control — placebo. duration was 30 days....