A5048960404- Phytochemicals and Antioxidant Activities
- Health Systems, Economic Evaluations, Quality of Life
- Antioxidant Activity and Oxidative Stress
- Economic and Financial Impacts of Cancer
- Essential Oils and Antimicrobial Activity
- Genomics, phytochemicals, and oxidative stress
- Cardiac Arrest and Resuscitation
- Gut microbiota and health
- Renal cell carcinoma treatment
- Glaucoma and retinal disorders
- Natural product bioactivities and synthesis
- RNA Research and Splicing
- Cholinesterase and Neurodegenerative Diseases
- Retinal and Macular Surgery
- Healthcare Policy and Management
- Global Health Care Issues
- Retinal Diseases and Treatments
- Tea Polyphenols and Effects
- Prostate Cancer Treatment and Research
- Chemistry and Chemical Engineering
- Nutrition, Genetics, and Disease
- Cardiac Ischemia and Reperfusion
- Cancer-related molecular mechanisms research
- Advanced Chemical Sensor Technologies
- Mechanical Circulatory Support Devices
Procter & Gamble (United States)
2023
University of Louisville
2017-2021
American Chemical Society
2018
Pharmerit (Netherlands)
2017-2018
Pennsylvania Academy of Science
2017
Long non-coding RNA (lncRNA) plasmacytoma variant translocation 1(PVT1) was aberrantly expressed in various cancers and is associated with tumor prognosis. Here, we aim to investigate its function prostate cancer. Small interfering against PVT1 transfected into cancer cell lines growth apoptosis were analyzed. Our results showed that overexpressed tissues cells. Higher levels of indicated poorer overall survival disease-free survival. A significant association found between expression stage....
Abstract Diets rich in fat, smoking, as well exposure to environmental pollutants and dysbiosis of gut microbiota, increase the risk developing colorectal cancer. Much progress has been made combating However, options for chemoprevention from insult microbiota remain elusive. We investigated influence berry-derived anthocyanidins (Anthos), with without encapsulating them bovine milk–derived exosomes (ExoAnthos), on bacteria-driven colon tumor development. Anthos ExoAnthos treatment cancer...
Structure-activity relationship (SAR)-based read-across is an important and effective method to establish the safety of a data-poor target chemical (structure interest (SOI)) using hazard data from structurally similar source chemicals (analogues). Many methods use quantitative similarity scores evaluate structural for searching selecting analogues as well evaluating analogue suitability. However, studies suggest that based purely on cannot accurately predict toxicity SOI. As mechanistic...
Colorectal cancer is the third most common form of diagnosed and leading class for cancer-related deaths. Given prevalence colon worldwide, further insight into developing novel effective prevention treatment strategies are warranted. The family plant pigments known as anthocyanins has been identified with a variety health benefits including chemopreventive therapeutic effects. A limitation to current clinical applications high doses that required. In order overcome this limitation, we...
Abstract Familial adenomatous polyposis (FAP) is an inherited disorder caused by mutations in the coli (APC) gene. If left untreated, nearly 100% of patients with FAP will eventually develop colorectal cancer, which third most common form cancer diagnosed men and women leading class for cancer-related deaths within United States. Given prevalence colon both States worldwide, further insight into developing novel more effective prevention treatment strategies are warranted. The family plant...