A5111773325- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Gastrointestinal disorders and treatments
- Vascular Tumors and Angiosarcomas
- Bone Tumor Diagnosis and Treatments
- Helicobacter pylori-related gastroenterology studies
- Epilepsy research and treatment
- Herpesvirus Infections and Treatments
- Air Quality and Health Impacts
- Infectious Diseases and Tuberculosis
- Pediatric Hepatobiliary Diseases and Treatments
- Metabolism and Genetic Disorders
- Cardiac tumors and thrombi
- Cerebral Palsy and Movement Disorders
- RNA modifications and cancer
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Cerebrospinal fluid and hydrocephalus
- Vasculitis and related conditions
- Glioma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Congenital Diaphragmatic Hernia Studies
- Cytomegalovirus and herpesvirus research
- Diverticular Disease and Complications
- Fetal and Pediatric Neurological Disorders
Tungs' Taichung MetroHarbor Hospital
2015-2025
National Chung Hsing University
2022-2024
China Medical University
2021-2023
Creative Commons
2023
Kang-Ning Junior College of Medical Care and Management
2019-2022
China Medical University Hospital
2021
Zunyi Medical University
2021
National Defense Medical Center
2000-2015
Tri-Service General Hospital
2000-2015
Abstract Epilepsy affects millions of people worldwide, necessitating effective and safe treatment options. Brivaracetam (BRV) levetiracetam (LEV) are antiepileptic drugs that target the synaptic vesicle protein 2A (SV2A). Despite similarities in their chemical structure, BRV LEV exhibit distinct pharmacological profiles. This study provides a detailed comparative analysis LEV, focusing on mechanisms action, preclinical profiles, pharmacokinetic pharmacodynamic properties. Clinical trial...
Mutant p53 (mutp53) commonly loses its DNA binding affinity to response elements (p53REs) and fails induce apoptosis fully. However, the mutation does not predict chemoresistance in all subtypes of breast cancers, critical determinants remain be identified. In this study, mutp53 was found mediate chemotherapy-induced long intergenic noncoding RNA-p21 (lincRNA-p21) expression by targeting G-quadruplex structure rather than p53RE on promoter promote chemosensitivity. estrogen receptor alpha...
Varicella is a common and mild disease in healthy children. However, when patients are immunocompromised conditions, such as receiving chemotherapy for cancer treatment, they highly vulnerable it can even prove lethal. Herein, we report 14-year-old boy with acute lymphoblastic leukemia who was induction vincristine, idarubicin, L-asparaginase, prednisolone, presented typical varicella skin lesions varicella-zoster virus detected his serum by real-time polymerase chain reaction (PCR). His...
Nifedipine, an L-type calcium channel blocker, is widely used in the treatment of hypertension and coronary heart diseases, also exhibits antiplatelet activity. Activation peroxisome proliferator-activated receptors (PPARs; α, β/δ, γ) inhibits platelet aggregation. Therefore, purpose this study was to evaluate contribution PPAR-mediated processes activity nifedipine.We assessed human aggregation by using aggregometer measured several activating markers related signaling pathways platelets...
Darstellung: Die mesenteriale Pseudozyste ist eine seltene, intraabdominelle Läsion. meisten Patienten mit mesenterialen Zysten sind symtomfrei. Symptomatische Zystengröße, Zystenlage und Komplikationen wie Infektion, Ruptur Hämorrhagie sowie intestinaler Obstruktion assoziiert. Der Volvulus seltene Komplikation der Zyste. Patient Methode: Wir berichten von einer 50-jährigen Frau kolikartigen epigastrischen Schmerzen über 3 Tage. Symptome verschlimmerten sich in Rückenlage besserten...
Background and Objectives: Drug-induced esophageal ulcer is caused by focal drug stimulation. It may occur in adults children. Limited research available pediatric patients with drug-induced ulcer; therefore, we designed this study to determine the characteristics of disease population. Materials Methods: Thirty-two diagnosed ulcers from a hospital database upper gastrointestinal tract endoscopies were included. After treatment, followed for 2 months after endoscopy. Results: Female...
Takayasu's arteritis (TA), a rare and lethal disease, always involves the aorta its branches.1 TA may present with hypertension, pulseless extremities, heart failure, death.2 Loss of monocular vision as first manifestation is uncommon.
Abstract Background Accidental swallowing of a foreign body occurs more frequently in children than adults. Among these cases, button battery impaction the esophagus may cause severe complications. While prevention is always ideal, if suspected, immediate diagnosis and retrieval are important. Case presentation We introduce novel method for after ingestion by 2.5-year-old child. When patient arrived at our center, was incarcerated upper esophagus. The could not be removed, despite use...
Background: Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) is a rare autosomal recessive disease. The incidence of estimated between 1/10,000 and 1/20,000 in Taiwan. Case report: This report describes case 42 day old female infant who suffered from prolonged jaundice, poor weight gain, anemia. initial total/direct bilirubin levels were 8.1/3.11 mg/dL. Liver biopsy was performed at 47 days old. pathology revealed lobules marked with macrovesicular microvesicular fatty...
We report the cases of two male preterm newborns with X-linked centronuclear myopathy (CNM). This is most severe type CNM. Each them presented generalized hypotonia, weakness, difficulty in swallowing, and respiratory distress at birth. Physical examination both revealed long thin face, high-arched palate, mild bilateral ptosis, frog-leg posture, absence deep tendon reflex. Diagnosis disease was made according to fetal history, family muscle histopathology, electron microscopy, genetic...
Background: Kawasaki disease (KD) is characterized by systemic vasculitis and may lead to coronary artery ectasia aneurysm. Autoantibodies, in particular anti-neutrophil cytoplasmic antibodies (ANCAs), have been identified association with the vasculitis. The relationship between ANCAs KD unclear. purpose of this study investigate role Taiwan. Methods: We assessed 10 patients (6 male 4 female; age range, months 3 years) January December 2003. Results: Cytoplasmic (c)-ANCA staining was absent...
Fibromatosis colli (FC) is a condition of benign fibrous tissue proliferation on one side the sternocleidomastoid (SCM) muscle leading to focal or diffuse enlargement neck and often clinically associated with torticollis. Here, we report case 2-month-old infant who was healthy except for bulky mass left SCM muscle. The patient diagnosed FC using sonography, which favored imaging tool because it can differentiate from other causes masses. Physiotherapy significantly improve majority cases.
This study aimed to present a systematic meta-analysis examining the association between Helicobacter pylori (H. pylori) infection, hemoglobin A1c levels, and development of type 1 diabetes mellitus. The initial search identified 451 articles related H. infection T1DM. Among them, 14 had 2,971 participants meeting inclusion criteria for advanced meta-analysis. A significant was observed T1DM, with an odds ratio (OR) 1.87 (95% confidence interval [CI]: 1.27–2.78, p = 0.002). subgroup analysis...
This study aimed to evaluate the early-childhood comorbidities of cerebral palsy (CP) in children with low birth weight (LBW) and assess impact maternal bio-psychosocial factors on risk CP preterm infants across varying weights. Data for 15,181 prematurely born from 2009 2013 151,810 matched controls Taiwan's National Health Insurance Research Database were analyzed. Period prevalence CP, LBW verified, odds ratios (ORs) calculated. Results confirmed that increasing prematurity rates...
On behalf of the editorial team, we are pleased to announce that Tungs' Medical Journal (TMJ) has been newly included in Directory Open Access Journals (DOAJ)[1]. Consequently, articles published from volume 18 (2024) onward will be indexed DOAJ's collection. TMJ was launched 2007, initially as a medical bulletin reporting most advanced research and hot topic reviews for staff Taichung MetroHarbor Hospital professionals other institutes. Over past 17 years, TMJ's team endeavored improve...
Abstract Intussusception is an intestinal disease usually occurring within 2 years of age. Most cases are idiopathic or caused by lymphadenopathy after viral infection. The rotavirus vaccine a kind oral live attenuated approved the Department Health in Taiwan since 2006. This reportedly increases risk intussusception, especially first dose. Herein, we report case intussusception dose vaccination with surgical findings that could clarify pathogenesis vaccine-induced intussusception.