A5042536412- Medicinal Plant Research
- Public Health and Nutrition
- Natural Products and Applications
- Computational Drug Discovery Methods
- Food and Agricultural Sciences
- Diverse Scientific Research Studies
- Natural Antidiabetic Agents Studies
- Agricultural and Biological Research
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Scientific and Engineering Research Topics
- Pineapple and bromelain studies
- Mercury impact and mitigation studies
- Herbal Medicine and Trade Cooperation
- Ginger and Zingiberaceae research
- Adolescent Health and Behaviors
- SARS-CoV-2 and COVID-19 Research
- Diet, Metabolism, and Disease
- Probiotics and Fermented Foods
- Medicinal Plants and Neuroprotection
- Protein Hydrolysis and Bioactive Peptides
- Microbial Metabolites in Food Biotechnology
- Light effects on plants
- COVID-19 Prevention and Impact
- Biochemical and Structural Characterization
Sam Ratulangi University
2013-2025
Universitas Islam Negeri Datokarama Palu
2023
Universitas Islam Negeri Sumatera Utara
2023
Institut Agama Islam Negeri Bengkulu
2019
Hasanuddin University
2016
Since the outbreak of COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that potential inhibit proliferation SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The present study aimed evaluate bioactive using a molecular docking approach main protease (Mpro) and spike (S) glycoprotein SARS-CoV-2. evaluation was performed on scores calculated AutoDock Vina (AV) as engine. A rule five (Ro5) determine...
Broccoli microgreens, rich in bioactive compounds, offer health benefits aligned with SDG 3: “Good Health and Well-Being.” Their antioxidants combat oxidative stress tied to chronic diseases, but drying can affect their activity. This study assessed the antioxidant capacities of fresh, microwave-dried, air-fryer-dried broccoli microgreens using vitro (DPPH assay) silico (molecular docking dynamics) methods. The were cultivated under controlled conditions dried microwave air-fryer techniques....
The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), which initially appeared in Wuhan, China, December 2019. Elderly individuals and those with comorbid conditions may be more vulnerable to this disease. Consequently, several research laboratories continue focus on developing drugs treat infection because has developed into a global pandemic an extremely limited number of specific treatments available. Natural herbal remedies have...
Since the beginning of coronavirus 19 (COVID-19) pandemic in late 2019, severe acute respiratory syndrome 2 (SARS-CoV-2) has been evolving through acquisition genomic mutations, leading to emergence multiple variants concern (VOCs) and interest (VOIs). Currently, four VOCs (Alpha, Beta, Delta, Gamma) seven VOIs (Epsilon, Zeta, Eta, Theta, Iota, Kappa, Lambda) SARS-CoV-2 have identified worldwide circulation. Here, we investigated interactions receptor-binding domain (RBD) five with human...
The rapid spread of a novel coronavirus known as SARS-CoV-2 has compelled the entire world to seek ways weaken this virus, prevent its and also eliminate it. However, no drug been approved treat COVID-19. Furthermore, receptor-binding domain (RBD) on viral spike protein, well several other important parts have recently undergone mutations, resulting in new virus variants. While treatment is currently available, naturally derived molecule with antiviral properties could be used potential...
Prostate cancer is a leading malignancy in men, ranking fourth globally and fifth Indonesia (GLOBOCAN 2020). Conventional therapies, though available, are limited by high costs, side effects, resistance, highlighting the need for accessible alternatives. Broccoli microgreens, rich bioactive compounds, have shown potential preventing treating various cancers. This study hypothesized that compounds broccoli microgreens interact with molecular targets involved prostate progression. To test this...
Before entering the cell, SARS-CoV-2 spike glycoprotein receptor-binding domain (RBD) binds to human angiotensin-converting enzyme 2 (hACE2) receptor. Hence, this RBD is a critical target for development of antiviral agents. Recent studies have discovered that variants with mutations in spread globally. The purpose silico study was determine potential fruit bromelain-derived peptide. DYGAVNEVK. inhibit entry various into cells by targeting hACE binding site within RBD. Molecular docking...
Knowledge of HIV and its transmission by women living with HIV/AIDS (WLWHA) attending clinic in lagos university teaching hospital (Luth), NigeriaJoda A. E., Bamkefa B.O., Olugbake O.
Chrysanthemum indicum L., commonly known as flower, is an herbaceous plant that has a long-established history of medicinal usage. There been extensive research about C. indicium L, especially its antioxidant activities, but not much done on fraction. This study aimed to explore the efficacy ethanol extract and fraction derived from flowers in scavenging free radicals. The potential extract, well aqueous n-hexane fractions, was evaluated using 2,2-diphenyl-1-picrilhidrazine (DPPH) method...
Organic waste, particularly from fruits, remains an environmental issue if not properly managed. These wastes have the potential to be reprocessed into products, one of which is beneficial for human health. The trend recycling fruit scraps ecoenzyme (EE), a fermented product, has increased in recent years. Several health advantages EE been highlighted. Therefore, this study aimed at evaluating antibacterial and antioxidant activity solutions derived papaya, pineapple, Kasturi orange. In...
The increased interest in exploring alternative treatments for type 2 diabetes mellitus is accompanied by a rise the prevalence of mellitus. Pineapple peel one by-products pineapple fruit and known to possess potential anti-diabetic activity. In this study, n-hexane extract was analyzed using network pharmacology methods ascertain its treating GC-MS analysis revealed presence 42 compounds, with 8 them considered safe as they met Lipinski Rule Five criteria drug-likeness were classified...
The risk of degenerative diseases is increasing due to unhealthy lifestyles. Many people consume junk food, smoke, and do not protect themselves from sun exposure pollution, exposing their bodies free radicals. Free radicals can cause oxidative stress, necessitating the need for antioxidants neutralize them. leilem plant (Clerodendrum minahassae) an endemic North Sulawesi that often used in traditional dishes medicine. Moreover, leaves are believed be a source natural antioxidants. This...
Traditional small-scale gold mining mostly use mercury to extract the from ores. However, contamination in environment can affect composition and structure of bacterial community. The purpose this study was determine effect on community traditional waste disposal site rice field. Mercury analysis carried out using CVAFS method. Analysis communities based results metabarcoding V3-V4 16S rRNA regions obtained paired-end Illumina MiSeq reads. showed that sample had a level 230 mg/kg, while...
Background and Objectives: The increasing occurrence prevalence of type-2 diabetes mellitus (T2DM) have led to a growing interest in researching available treatment alternatives. Clerodendrum minahassae, native plant species North Sulawesi, has been focus ethnopharmacological studies due its significance contributions drug development, particularly potential antidiabetic properties. This study investigated the pharmacological minahassae (CM) leaf extract for managing using network...
Background: Psychosis, marked by detachment from reality, includes symptoms like hallucinations and delusions. Traditional herbal remedies kratom are gaining attention for psychiatric conditions. This was aimed at comprehending the molecular mechanisms of Kratom's antipsychotic effects utilizing a multi-modal computational approach. Materials Methods: study employed network pharmacology followed docking dynamics simulation to investigate potential properties compounds identifying their key...
The prevalence of degenerative diseases has been escalating due to the mounting presence oxidative stress conditions, characterized by elevated levels reactive oxygen species (ROS). Oxidative triggers genetic alterations, structural modifications, and progression various disorders, including cancer, diabetes, Parkinson’s disease, Alzheimer’s rheumatoid arthritis, osteoporosis. Consequently, modulation redox homeostasis attenuation through activity antioxidant compounds play crucial roles....