A5060944917- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Computational Drug Discovery Methods
- Synthesis and biological activity
- Chemical synthesis and alkaloids
- Diverse Scientific Research Studies
- Plant tissue culture and regeneration
- Medicinal Plants and Neuroprotection
- Ethnobotanical and Medicinal Plants Studies
- Botanical Research and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Mangiferin and Mango Extracts
- Ginseng Biological Effects and Applications
- Psidium guajava Extracts and Applications
- Moringa oleifera research and applications
- Phytochemistry and Bioactivity Studies
- Crystallography and molecular interactions
- Microbial Metabolites in Food Biotechnology
- Pharmacological Effects of Natural Compounds
- Medicinal Plant Research
- Synthesis and Characterization of Heterocyclic Compounds
- Traditional and Medicinal Uses of Annonaceae
- Medicinal Plant Extracts Effects
- Plant and Biological Electrophysiology Studies
International Islamic University Chittagong
2020-2024
University of Dhaka
2020-2021
Since the outbreak of COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that potential inhibit proliferation SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The present study aimed evaluate bioactive using a molecular docking approach main protease (Mpro) and spike (S) glycoprotein SARS-CoV-2. evaluation was performed on scores calculated AutoDock Vina (AV) as engine. A rule five (Ro5) determine...
Dita bark (Alstonia scholaris (L.) R. Br.) is an ethnomedicine used for the management of various ailments. This study aimed to investigate biological properties methanol extract A. (MEAS), through in vivo, vitro and silico approaches alongside its phytochemical profiling. Identification nature bioactive secondary metabolites were studied by established qualitative tests GC–MS analysis. The antidepressant activity was determined forced swimming test (FST) tail suspension (TST) mice....
Cycas pectinata Buch.-Ham. is commonly used in folk medicine against various disorders. The present study investigated the antidepressant and cytotoxicity activity of methanol extract C. (MECP) along with quantitative phytochemical analysis by GC-MS method. Here, MECP presented 41 compounds, among which most were fatty acids, esters, terpenoids oximes. was assessed forced swimming test (FST) tail suspension (TST) models. In contrast, (200 400 mg/kg) exhibited a significant dose-dependent...
The present study explores the neuropharmacological, antinociceptive, antidiarrheal, antioxidant, thrombolytic and cytotoxic activity of methanol extract Psychotria calocarpa leaves (MEPC). In anxiolytic testing MEPC by elevated plus maze test, hole–board test light–dark exhibited a dose-dependent reduction anxiety while open field observed decreased locomotion. administration revealed significant depressant behavior in forced swimming tail suspension test. Additionally, antinociceptive...
Millettia peguensis, popular for its ethnopharmacological uses, was employed to evaluate different pharmacological properties in this study. The analgesic studies of the plant have been performed by acetic acid-induced writhing and formalin-induced licking tests respectively, whereas antidiarrheal experiment done castor oil-induced diarrheal test. Besides, antioxidant, cytotoxic, antimicrobial, thrombolytic evaluations were DPPH scavenging with phenol content determination, brine shrimp...
The outbreak of coronavirus disease (COVID-19) caused by a novel RNA virus emerged at the end 2019. Most patient's symptoms are mild to moderate, and influenza, acute respiratory distress syndrome (ARDS) multi-organ failure common. is moderate in most patients reported many cases such as pneumonia, ARDS dysfunction. This study's objective evaluate 25 natural compounds from Citrus limon (CL) used comprehensive molecular docking, density functional theory (DFT) dynamics analysis against...
The anti-inflammatory, thrombolytic, and hair growth-promoting activity of the n-hexane fraction from methanol extract Leea indica (NFLI) leaves was investigated. NFLI showed significant inhibition hemolysis protein denaturation, exhibited a concentration-dependent thrombolytic activity. When applied topically to mice at concentrations 10, 1, 0.1%, demonstrated increase in average length (p < 0.001) compared with untreated animals. (1% concentration) highest percentage regrowth on day 7,...
Abstract Covid-19 is a global pandemic where an effective drug has yet to be found. A new coronavirus species, SARS-CoV-2 causes this disease. Several studies have been conducted on medicinal plant-based lead compounds find antidotes for virus. One of the fruits that with high betacyanin content super red dragon fruit produced by plant Hylocereus costaricensis . Betacyanin, besides having anti-inflammatory and immunomodulatory activities, also antiviral activity. Therefore, study aimed...
Mangifera longipes and Quercus gomeziana both is an ethnomedicinally important Asian herb that has been known for numerous healing activity of tribal people. The present research aims to investigate the phytochemical analysis with in vitro, vivo possibilities soluble ethanol extract M. root (EEMLR) Q. leaves (EEQGL) by experimental approach. plant EEMLR EEQGL was found secondary metabolites, notably steroids, glycosides, tannins, flavonoids, saponins, gums, alkaloids. Additionally, showed...
Pani heloch (Antidesma montanum) is traditionally used to treat innumerable diseases and a source of wild vegetables for the management different pathological conditions. The present study explored qualitative phytochemicals; quantitative phenol flavonoid contents; in vitro antioxidant, anti-inflammatory, thrombolytic effects; vivo antipyretic analgesic properties methanol extract A. montanum leaves experimental models. exhibited secondary metabolites including alkaloids, flavonoids,...
The development of novel and safe compounds is a challenging task in the drug discovery trajectory. Accordingly, individuation promising core molecules with biological activities could pave way to develop effective drugs treat given disease. use computational approach can reduce time for identifying characterizing their potential pharmacological profile providing hints synthesis derivatives increased predicted activity. Following this strategy, starting from molecule thiazolidine-2,4-dione,...
Chukrasia velutina is an enthnomedicinally used plant reported to have significant medicinal values. The present study aimed explore the pharmacological activities of bark methanol extract using in vitro, vivo and silico models.
The methanol extract of the leaves Tabernaemontana pauciflora (METP) was screened to investigate semi-qualitative phytochemical, in vivo anti-depressant, anxiolytic and vitro thrombolytic activities. antidepressant activity METP examined by Force swimming test (FST) Tail suspension (TST) whereas using Hole-board (HBT) Elevated plus maze (EPM) on mice model. model used check clot lysis effect METP. Additionally, phytochemical assay performed through test. In activity, exhibited significant...