A5102995706- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Asthma and respiratory diseases
- Eosinophilic Esophagitis
- Drug-Induced Adverse Reactions
- Diabetes Management and Research
- Diabetes and associated disorders
- Eosinophilic Disorders and Syndromes
- Respiratory and Cough-Related Research
- Urticaria and Related Conditions
- Immunodeficiency and Autoimmune Disorders
- Autoimmune Bullous Skin Diseases
- Pancreatic function and diabetes
- Food Safety and Hygiene
- Metabolism and Genetic Disorders
- Skin and Cellular Biology Research
- Entomological Studies and Ecology
- Respiratory viral infections research
- Mast cells and histamine
- Viral Infections and Immunology Research
- Transgenic Plants and Applications
- Italian Social Issues and Migration
- Eating Disorders and Behaviors
- Inhalation and Respiratory Drug Delivery
Ospedale Pediatrico Giovanni XXIII
2020-2024
University of Bari Aldo Moro
2012-2022
University of Parma
2015-2021
Charité - Universitätsmedizin Berlin
2016-2019
Ospedale di Parma
2016-2017
Pollen-food syndrome (PFS) is heterogeneous with regard to triggers, severity, natural history, comorbidities, and response treatment. Our study aimed classify different endotypes of PFS based on IgE sensitization panallergens.We examined 1271 Italian children (age 4-18 years) seasonal allergic rhinoconjunctivitis (SAR). Foods triggering were acquired by questionnaire. Skin prick tests performed commercial pollen extracts. panallergens Phl p 12 (profilin), Bet v 1 (PR-10), Pru 3 (nsLTP)...
The gold standard test for confirming whether a child has clinical hypersensitivity reactions to foods is the oral food challenge. Therefore, there increasing interest in simpler diagnostic markers of allergy, especially children, avoid goal this study was assess accuracy atopy patch comparison with challenge.We investigated 243 children (mean age, 51 months) referred evaluation suspected egg or cow's milk allergy. Skin prick and were carried out, after 2 weeks elimination diet, challenge...
Grass pollen-related seasonal allergic rhinoconjunctivitis (SARg) is clinically heterogeneous in severity, comorbidities, and response to treatment. The component-resolved diagnostics disclosed also a high heterogeneity at molecular level. Our study aimed analyzing the characteristics of IgE sensitization Phleum pratense molecules investigating diagnostic relevance such childhood.We examined 1120 children (age 4-18 years) with SARg. Standardized questionnaires on atopy were acquired through...
Treatment of IgE-mediated food allergy involves avoiding the causing allergic reaction. In association, an action plan for reactions is indicated, sometimes including self-injectable adrenaline. addition to these dietary and medical implications, there are two equally important ones: nutritional psychosocial. From a point view, it known that children suffering from have growth delay in height weight compared their non-allergic peers. Specifically, this condition directly related specific...
Pollen-related seasonal allergic rhinoconjunctivitis (SAR) is a very frequent pediatric disease in Westernized countries. Risk factors and phenotypes have been thoroughly examined several cross-sectional studies. By contrast, only few studies evolution patient cohorts. We investigated predictive biomarkers of large cohort children with SAR.During 2015-2017 (follow-up), we re-examined 401 patients from those enrolled 2009-2011 (baseline) by the "Panallergens Pediatrics" study, multicenter...
Vaccines often contain potentially allergenic material in addition to pathogen-specific immunogens that may induce allergic reactions. Parents and physicians suspect adverse reactions vaccines are etiology. The concern some of the substances contained trigger an anaphylactic reaction lead a low vaccination adherence with emergence infectious disease epidemics.To provide practical suggestions for managing children suspected have vaccine.Information was obtained from search guidelines relevant...
To analyze clinical characteristics associated with the occurrence of diabetic ketoacidosis (DKA) at onset type 1 diabetes (T1D) in children aged <5 years order to identify early signs or symptoms useful prevent DKA appearance.Data patients newly diagnosed TID (Group 1) and 6-10 old 2) coming from province Parma were collected period 2012-2016.Mild/moderate diagnosis occurred more frequently Group than 2 (p<0.0015). Severe incidence was higher below 5 (21.8%) those over age (3.75%; p=0.021)....
to investigate how much effectiveness of the historical campaign DKA prevention at T1D diagnosis has survived in Parma's province where this was launched Nineties, and it spontaneously spread neighboring provinces.children aged 6-14 years with newly diagnosed TID coming from Parma (Group 1) two other nearby provinces 2) were investigated. Clinical laboratory data retrospectively collected medical files each patient included age, gender, capillary pH, serum bicarbonate, 3-beta-hydroxybutyrate...
Abstract Allergic diseases have different frequencies. In particular, allergic rhinitis and asthma high frequencies of about 20% 10%, respectively. Other lower frequencies; for example, food allergy has a frequency 1%‐4%. There are also rare diseases, with prevalence 5 cases per 10 000 people in the general population, they included Orphanet. However, other extremely still need to be properly known order possibly recognized as cataloged
Physical activity (PA) can be associated with better health-related quality of life (HRQoL). This study aimed to assess HRQoL before and after a two-week summer program promoting PA in Italian school-aged children. Participants were recruited during the Giocampus summer2017 (Parma, Italy), from June July. Before (T0) (T1) program, children one their parents answered Kindl questionnaire. For each domain, least-square mean changes (LSmc) at T1 derived linear regression models stratified by...
Angioedema (AE) is a vascular reaction of subcutaneous and submucosal tissues that identifies various clinical pictures often associated with wheals. AE without wheals (AEwW) infrequent. The ability to distinguish between AEwW mediated by mast cells bradykinin-mediated or leukotriene-mediated pathways crucial for correct diagnostic-therapeutic follow-up approach. can be hereditary acquired. Factors typically correlated angioedema (HAE) are recurrence episodes, familiarity, association...
To verify the possible advantages of 3- β-hydroxybutyrate (3HB) measurement compared to urinary assay ketones during an intercurrent disease managed at home.Twelve Pediatricians were asked enroll least 4 patients aged 3 5 years, affected by illness and showing one symptoms reliable ketosis. Recruited submitted simultaneous 3HB in capillary blood urine (T3) 6 hours (T6) from first (T0). For ketone detection commercial tests used.Thirty-eight children (4.36±2.60 years old; 25 boys) enrolled...
To analyze the effectiveness of a tailored medical support to help children from ethnic minorities achieve same good metabolic control autochthonous peers with type-1 diabetes (T1D).Children <10 years age belonging minority (EM) families (Group 1) were compared 2) who received diagnosis T1D in 2014-2016. The Protocol for included other than standard protocol: booklets translated languages; weekly visits at home or school; family-guides; clinic supported by professional interpreters. After...