In recent years, a deep convolutional neural network (DCNN) has attracted great attention due to its outstanding performance in recognition of natural images. However, the DCNN for medical image is still uncertain because collecting large amount training data difficult. To solve problem DCNN, we adopt transfer learning strategy, and demonstrate feasibilities strategy mass detection mammographic We architecture that consists 8 layers with weight, including 5 layers, 3 fully-connected this...

Abstract With the popularization of pulse wave signals by spread wearable watch devices incorporating photoplethysmography (PPG) sensors, many studies are reporting accuracy rate variability (PRV) as a surrogate heart (HRV). However, authors concerned about their research paradigm based on assumption that PRV is biomarker reflects same biological properties HRV. Because PPG and ECG R both reflect periodic beating heart, should be equal, but it does not guarantee respective variabilities also...

Abstract Stress is a known trigger of irritable bowel syndrome (IBS) and exacerbates its gastrointestinal symptoms. However, underlying the physiological mechanism remains unknown. Here, we investigated hypothalamic–pituitary–adrenal (HPA) axis, colonic motility, autonomic responses to corticotropin-releasing hormone (CRH) administration as well brain activity alterations in IBS. The study included 28 IBS patients 34 age sex-matched healthy control subjects. demonstrated greater...

It is important to know about a sudden blood pressure change that occurs in everyday life and may pose danger human health. However, monitoring the variation daily difficult because bulky expensive sensor needed measure continuously. In this study, new non-contact method proposed estimate using video images. method, pulse propagation time difference or instantaneous phase calculated between two waves obtained from different parts of subject's body captured by camera. The forehead, left...

Microphthalmia-associated transcription factor (MITF) is a basic helix-loop-helix-leucine zipper protein, and plays an important role in the development of various cell types, such as neural-crest-derived melanocytes optic-cup-derived retinal pigment epithelium. Three isoforms MITF with distinct amino-termini have been described. These include melanocyte lineage-specific MITF-M, heart-type MITF-H, recently identified MITF-A. Here we identify fourth isoform, MITF-C, unique amino-terminus 34...

The presence of microcalcification clusters (MCs) in mammogram is a major indicator breast cancer. Detection an MC one the key issues for cancer control. In this paper, we present highly accurate method based on morphological image processing and wavelet transform technique to detect MCs mammograms. microcalcifications are firstly enhanced by using multistructure elements processing. Then, candidates refined multilevel reconstruction approach. Finally, detected their distributions feature....

Impedance cardiography (ICG) may be altered by noises as respiration and movement artifacts, mainly during exercise. In this work, a scaled Fourier linear combiner (SFLC) event-related to the R-R interval of ECG is proposed. It estimates deterministic component impedance cardiographic signal removes uncorrelated interval. The modeled series with coefficients estimated least mean square (LMS) algorithm. Simulations have been carried out evaluate filter performance for different noise...

In traditional Chinese medicine, moxibustion is a local thermal therapy that used for several conditions. Quantifying the effects of has been difficult because treatment temperature depends on physician's experience, and distribution in target area not uniform. This prospective observational study aims to quantify effect stimulation abdomen. We developed heat transfer control device (HTCD) stimulation. Twenty-four healthy subjects were enrolled they underwent abdominal para-umbilical region...

Background . The relation between glaucoma and retrobulbar circulation in the prognosis has been indicated. Purpose To investigate effects of acupuncture on open‐angle (OAG) patients. Methods Eleven OAG patients (20 eyes with OAG) who were treated by topical antiglaucoma medications for at least 3 months enrolled. Acupuncture was performed once acupoints BL2, M‐HN9, ST2, ST36, SP6, KI3, LR3, GB20, BL18, BL23 bilaterally. Retrobulbar measured color Doppler imaging, intraocular pressure (IOP)...

Markerless tracking of respiration-induced tumor motion in kilo-voltage (kV) fluoroscopic image sequence is still a challenging task real time image-guided radiation therapy (IGRT). Most existing markerless methods are based on template matching technique or its extensions that frequently sensitive to non-rigid deformation and involve expensive computation. This paper presents kernel-based method capable kV with robust performance low computational cost. The proposed system consists the...

To develop a markerless tracking algorithm to track the tumor boundary in megavoltage (MV)-electronic portal imaging device (EPID) images for image-guided radiation therapy.A level set method (LSM)-based is developed EPID image sequences. Given an sequence, initial curve manually specified first frame. Driven by region-scalable energy fitting function, automatically evolves toward and stops on desired while function reaches its minimum. For subsequent frames, updates using result previous...

Abstract: A vibrating flow pump (VFP), which can generate oscillated blood (10–50 Hz/min), has been developed by our team for the artificial heart system. However, pattern of this was different from that natural heart; therefore, it is important to analyze effect on circulatory regulatory To hemodynamics high frequency as an entity, (not decomposed), nonlinear mathematical techniques were utilized. VFPs implanted between left atrium in animal experiments using adult goats. After implantation...

The present study has proposed a new method for estimating the pressure head (P (t)[mm Hg]) and flow (Q (t)[L/min]) of centrifugal pump on basis voltage (V (t)[V]), current (I (t)[A]), rotational speed (N (t)[k(rpm)]) DC motor without any additional sensors. In estimation method, two auto-regressive exogenous (ARX) models are employed. One ARX model an output, P (t) or Q (t), three inputs, VI =V I N steady state gain (K) system from to (t). It can be assumed that K may include information...

To determine the effect of left ventricular assist device (LVAD) pumping on sympathetic tone, renal nerve activity (RSNA) was detected in acute animal experiments. Our TH-7B pneumatically driven, sac-type used 7 adult mongrel dogs. RSNA by use bipolar electrodes attached to nerve. amplified and integrated an R-C integrator circuit. The area discharge per unit time calculated computer system expressed as time. During LVAD pumping, decreased with increase blood pressure, pulmonary artery flow,...

Abstract Background Taking advantage of developed image technology, it is expected that presentation would be utilized to promote health in the field medical care and public health. To accumulate knowledge on biomedical effects induced by presentation, an essential prerequisite for these purposes, studies autonomic responses more than one physiological system necessary. In this study, changes parameters pupillary light reflex cardiovascular evoked motion pictures were examined, which...

Daikenchuto is a traditional herbal medicine that used for the treatment of cold feeling in abdomen, while Orengedokuto, also medicine, treating inflammatory and ulcerative diseases affecting internal organs. However, effects these medicines on cardiac output (CO) intestinal blood flow have never been investigated. This examiner-blinded randomized crossover study intended to clarify influence Orengedokuto CO volume superior mesenteric artery (SMA). Fourteen healthy men (35 ± 7 years old)...

Background: Pulse diagnosis of the peripheral artery is an important technique in Traditional Chinese Medicine, where, acupuncture therapy, treatment adjusted according to observed changes pulse. We investigated change blood flow and cardiac index during treatment. Objectives: The aim this study explore effect on radial brachial volume healthy subjects. Methods: Eighteen (18) volunteers were enrolled. Acupuncture was performed bilaterally LR-3 with manual rotation needles. pressure heart...

Feasibility of computer-aided diagnosis (CAD) systems has been demonstrated in the field medical image diagnosis. Especially, deep learning based CAD showed high performance thanks to its capability recognition. However, there is no system developed for post-mortem imaging and thus it still unclear if effective this purpose. Particulally, drowning one most difficult tasks forensic medicine because findings are not specific. To address issue, we develop a consisting convolution neural network...

The continuous measurement of percutaneous oxygen saturation (SpO2) enables diseases that cause hypoxemia to be detected early and patients' conditions monitored. Currently, SpO2 is mainly measured using a pulse oximeter, which, owing its simplicity, can used in clinical settings at home. However, the oximeter requires sensor contact with skin; therefore, prolonged use for neonates or patients sensitive skin may local inflammation stress due restricted movement. In addition, COVID-19, there...

The effects of age on the circadian blood pressure rhythm patients with untreated essential hypertension (n=133, World Health Organization stage I or II) were compared those normotensive subjects (n=91). Subjects classified into three groups by age: young (<40 years old), adult (40-59 old) and old (>60 old). Blood was monitored every 5 min for 24 h, using a finger volume oscillometric device under fixed external conditions. single cosinor method used to evaluate rhythm. There no difference...

Pharmacological support with inotropes and vasodilators to control decompensated hemodynamics requires strict monitoring of patient condition frequent adjustments drug infusion rates, which is difficult time-consuming, especially in hemodynamically unstable patients. To overcome this difficulty, we have developed a novel automated delivery system for simultaneous systemic arterial pressure (AP), cardiac output (CO), left atrial (Pla). Previous systems attempted directly AP CO by estimating...

Hemispatial neglect is a common disorder that can occur after lesion in the right hemisphere. Its main characterization difficulty processing visual stimuli emanating from space contralateral to lesion. Pencil and paper tests (such as target cancellation, line bisection, or drawing copy) are used diagnose neglect. We propose using virtual reality technology haptic force feedback enhance pencil tests. Our system track patients' eye-gaze their hand movements. Also, efficiency of several...