A5028482118- Cardiac electrophysiology and arrhythmias
- Cardiac Arrest and Resuscitation
- Cardiovascular Effects of Exercise
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Ischemia and Reperfusion
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Electrolyte and hormonal disorders
- Cardiovascular Syncope and Autonomic Disorders
- Neuroscience of respiration and sleep
- Hormonal and reproductive studies
- Cardiac pacing and defibrillation studies
- Health Systems, Economic Evaluations, Quality of Life
- Takotsubo Cardiomyopathy and Associated Phenomena
- Mitochondrial Function and Pathology
- Cardiac Fibrosis and Remodeling
- Cardiovascular Disease and Adiposity
- Dialysis and Renal Disease Management
- Receptor Mechanisms and Signaling
- Cannabis and Cannabinoid Research
- Potassium and Related Disorders
Copenhagen University Hospital
2017-2024
Rigshospitalet
2017-2024
Patients with atrial fibrillation (AF) are at increased risks of cardiovascular diseases and mortality, but according to age diagnosis have not been reported. This study investigated age-specific outcomes among patients AF the background population.
Importance Sudden infant death syndrome (SIDS) remains a leading cause of during the first year life. The etiology SIDS is complex and largely unknown. Objective To evaluate whether siblings children who died have higher risk compared with general pediatric population. Design, Setting, Participants This register-based cohort study used Danish nationwide registers. were all infants (<1 year) in Denmark between January 1, 1978, December 31, 2016, including SIDS. Siblings followed up...
Background Potassium disturbances per se increase the risk of ventricular fibrillation (VF). Whether potassium in acute phase ST-segment-elevation myocardial infarction (STEMI) are associated with VF before primary percutaneous coronary intervention (PPCI) is uncertain. Methods and Results All consecutive STEMI patients were identified Eastern Danish Heart Registry from 1999 to 2016. Comorbidities medication use assessed nationwide registries. levels collected immediately PPCI start....
Abstract Aims The current knowledge of idiopathic ventricular fibrillation (IVF) is limited. We aimed to investigate the nature IVF, including clinical assessment and later diagnosis, risk factors implantable cardioverter defibrillator (ICD) therapy in follow‐up period. Methods Between 2007 2019 we systematically identified all patients from Rigshospitalet, Denmark, with a resuscitated sudden cardiac arrest (SCA) no identifiable cause. All were followed routinely ICD outpatient clinic...
The underlying biological mechanisms of ventricular fibrillation (VF) during acute myocardial infarction are largely unknown. To our knowledge, this is the first proteomic study for trait, with aim to identify and characterize proteins that associated VF ST-elevation (STEMI). We included 230 participants from a Danish ongoing case-control on patients STEMI (case, n = 110) without (control, 120) before guided catheter insertion primary percutaneous coronary intervention. plasma proteome was...
Febrile seizure (FS) is a common disorder affecting 2–5% of children up to 5 years age. The aim this study was determine whether FS in early childhood are over-represented young adults dying from sudden cardiac death (SCD). We included all deaths (n = 4595) nationwide and through review certificates, we identified 245 SCD Danes aged 1–30 2000–09. Through the usage registries, persons admitted with first among cases (14/245; 5.7%) corresponding living Danish population (71 027/2 369 785;...
The aim of this study was to compare short- and long-term risk sudden cardiac death (SCD) among persons aged 18-49 years with without chronic kidney disease (CKD).Using Danish nationwide health registries, all diagnosed earlier stages CKD or failure from 1 July 1995 through 2009 were identified. Non-exposed subjects matched on sex birth-year All SCD in the population 2000-2009 have previously been identified using information certificates, autopsy reports. In total, 9308 incident cases stage...
Emerging data show that complete revascularization (CR) reduces cardiovascular death and recurrent myocardial infarction in ST-segment elevation (STEMI). However, the influence of status on development arrhythmia long-term post-STEMI phase is poorly described. We hypothesized incomplete (ICR) compared with CR STEMI associated an increased risk new-onset arrhythmia.Patients treated primary percutaneous coronary intervention (PPCI) at Copenhagen University Hospital, Rigshospitalet, Denmark, or...
Aims To investigate seasonality and association of increased enterovirus influenza activity in the community with ventricular fibrillation (VF) risk during first ST-elevation myocardial infarction (STEMI). Methods This study comprised all consecutive patients STEMI (n = 4,659; aged 18–80 years) admitted to invasive catheterization laboratory between 2010–2016, at Copenhagen University Hospital, Rigshospitalet, covering eastern Denmark (2.6 million inhabitants, 45% Danish population)....
We present the case of a relative patient with catecholaminergic polymorphic ventricular tachycardia. This underwent standard (Bruce) exercise stress test (EST), which had normal results. He then our modified "sprint" EST, positive report underlines how sprint EST may provoke arrhythmias better than Bruce EST. (Level Difficulty: Advanced.).
Cardiac arrest (CA) survivors with left/right bundle branch block (LBBB/RBBB) and no ischemic heart disease (IHD) have not been previously characterized. The aim of this study was to describe failure, implantable cardioverter defibrillator (ICD) therapy mortality in population.Between 2009 2019 we consecutively identified all CA a consistent (BBB) defined as QRS ≥ 120 ms, who had secondary prophylactic ICD implanted. Patients congenital were excluded.Among 701 CA-survivors survived discharge...
Abstract Introduction Prediction of recurrent ventricular arrhythmia (VA) in survivors an out‐of‐hospital cardiac arrest (OHCA) is important, but currently difficult. Risk recurrence may be related to presence myocardial scarring assessed with late gadolinium enhancement magnetic resonance (LGE‐CMR). Our study aims characterize as defined by LGE‐CMR a VA‐OHCA and investigate its potential role the risk new VA events. Methods Between 2015 2022, total 230 patients without ST‐segment elevation...
Background: AARS2 encodes the mitochondrial protein alanyl-tRNA synthetase 2 (MT-AlaRS), an important enzyme in oxidative phosphorylation. Variants have previously been associated with infantile cardiomyopathy. Case summary: A 4-year-old girl died of infantile-onset dilated cardiomyopathy (DCM) 1996. Fifteen years later, her 21-year-old brother was diagnosed DCM and ultimately underwent heart transplantation. Initial sequencing 15 genes discovered no pathogenic variants at time his...
Introduction: Emerging data show that complete revascularization reduces cardiovascular death and recurrent myocardial infarction in ST-segment elevation (STEMI). The influence of status on development arrhythmia the chronic post-STEMI phase is poorly described. Hypothesis: We hypothesized incomplete compared with STEMI associated an increased long-term risk new-onset arrhythmia. Methods: Using unique Danish registries, was assessed or after primary percutaneous coronary intervention (PPCI)...