<h3>Importance</h3> A connection between Meniere disease (MD) and migraine has been proposed, but the temporal association remains unknown. <h3>Objective</h3> To examine bidirectional of MD with migraine. <h3>Design, Setting, Participants</h3> This case-control study included participants 40 years or older from Korean National Health Insurance Service Screening Cohort 2002 to 2015. <h3>Main Outcomes Measures</h3> total 6919 patients were matched 27 676 control without for age, sex, income,...

Thyroid dysfunction is linked to an increased risk of cognitive impairment. However, studies on the relationships between thyroid diseases and Alzheimer's disease (AD) have reported conflicting results. We investigated associations several AD in a nested case-control study.

Objectives. We evaluated changes in income levels a hearing-impaired population.Methods. The study subjects were selected from the Korean National Health Insurance Service-Health Screening Cohort data 2002 to 2015 of Koreans ≥40 years old. In total, 5,857 matched with 23,428 comparison participants. Differences between initial level and at 1, 2, 3, 4, 5 post-enrollment compared groups. interaction time hearing impairment/comparison was estimated.Results. Both group showed increased over...

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of factors causing systemic bone destruction that may lead to osteoporosis development. The association between and has been documented; however, the findings remain unclear. This study aimed identify using cross-sectional design Korean Genome Epidemiology Study (KoGES) health examinee data. Methods used epidemiological data from KoGES during 2004–2016. Of 125,324...

An association between anemia and an increased risk of osteoporosis has been suggested. The goal this study was to estimate the hemoglobin (Hb) level with osteoporosis. A total 69,760 patients aged ≥ 40 years old from Korean National Health Insurance Service Screening Cohort were enrolled. From identical cohort database, comparison participants randomly selected. Hb levels before onset evaluated. analyzed using a conditional logistic regression model adjusted for obesity, smoking status,...

This study aimed to investigate changes in the exercise pattern and dietary habits adolescents during COVID-19 pandemic. The 12-18-year-old population Korea Youth Risk Behavior Web-Based Survey data of 2019 2020 was enrolled. 105,600 participants (53,461 group 52,139 group) were compared. odds ratios (ORs) for compared analyzed using multiple logistic regression analysis with complex sampling. eating fruit, drinking soda, sweet drinks, consuming fast food lower than (all p < 0.001)....

Recent research suggests a potential relevance between chronic periodontitis (CP) and Parkinson’s disease (PD), raising concerns about comorbid PD among elderly CP patients. However, the epidemiologic basis for this association remains unclear. Employing nested case-control design, study explored subsequent occurrences in Korean adults, leveraging validated national population-based dataset covering period from 2002 to 2019. It included 8794 patients 35,176 matched control individuals,...

Abstract The association of thyroid disease and Ménière’s would suggest that both are autoimmune diseases. This study aimed to investigate the relation goiter, hypothyroidism, thyroiditis, hyperthyroidism, thyroiditis with disease. Korean National Health Insurance Service-Health Screening Cohort data from 2002 through 2015 were used. 8183 adult patients 1:4 matched 32,732 individuals control group for age, sex, income, region residence. previous histories disorders including hyperthyroidism...

Proton pump inhibitors (PPIs) are widely used for acid-related gastrointestinal disorders, but their potential association with lung cancer risk and mortality remains underexplored debated. This study sought to investigate the between PPI use likelihood mortality, focusing on impact of exposure history duration. utilized data from 6795 patients, 27,180 matched controls, 4257 deceased 2538 surviving patients Korean National Health Insurance Service's Screening Cohort (2002-2019). Propensity...

Hyperuricemia arises from the buildup of excessive uric acid in blood, and it is implicated development periodontitis. The objective this study was to investigate association between hyperuricemia periodontitis using a cross-sectional design Korean Genome Epidemiology Study Health Examinee (KoGES HEXA) data. This prospective cohort used epidemiological data KoGES 2004 2016. Among 173,209 participants, 8809 with 126,465 controls (non-hyperuricemia) were selected. defined as >7.0 mg/dL men...

Abstract Background Few studies have examined the association between physical activity (PA) and various causes of mortality in Korea. The aim our study was to evaluate death PA insufficient using Korean national cohort data. Methods health screening data from National Health Insurance Service-National Sample Cohort 2009 2015 were used. ‘PA’ determined if participants walked or performed moderate-intensity ≥5 d/week for ≥30 min, vigorous-intensity ≥3 ≥20 min. Other classified as...

Oral health can affect or be a manifestation of general health. Although oral assessment has been used as proxy for health, few studies have reported an association between status and allergic diseases. This cross-sectional study aimed to investigate the relationship subjective asthma/allergic rhinitis in nationwide representative sample Korean adults.A total 227,977 participants from Community Health Survey 2015 were enrolled. Participants asked about their (very good, normal, poor, very...

Objective: The association between periodontitis and benign prostatic hyperplasia (BPH) has been controversial. This study aimed to estimate the recurrent episodes occurrence of BPH in an adult male population Korea. Methods: analyzed data from 79,497 matched cases controls examine relationship BPH, using Korean National Health Insurance Service-Health Screening Cohort data. Conditional logistic regression was used calculate odds ratios (ORs) with 95% confidence intervals (CIs), adjusting...

Chronic periodontitis (CP) has been linked to an increased risk of sudden sensorineural hearing loss (SSNHL). This study aimed delineate the causal relationships between CP and SSNHL. Data from 40-year-old participants in Korean National Health Insurance Service-Health Screening Cohort 2002 through 2019 were used. The data 13,769 patients with SSNHL collected matched those 55,076 control terms demographic socioeconomic variables. incidence before onset was recorded. odds ratios (ORs) for...

Background/Objectives: Parkinson's disease (PD) and benign paroxysmal positional vertigo (BPPV) are both prevalent in the geriatric population. While dizziness is a common non-motor symptom PD, relationship between PD incident BPPV remains unclear. Limited data suggest potential shared mechanisms, including mitochondrial dysfunction oxidative stress, but large-scale epidemiological evidence lacking. This investigation focused on assessing incidence of patients with compared to matched...

This study aimed to investigate the association of income level with susceptibility coronavirus disease 2019 (COVID-19) and COVID-19 morbidity mortality. Using Korean National Health Insurance Database cohort, medical claim data from 2015 through 2020 were collected. A total 7943 patients who diagnosed 1 January 4 June included. 118,914 participants had negative PCR tests. Income levels classified by 20th percentiles based on premiums. The percentile categorized into three groups (low,...

Previous studies have reported the association of obesity with increased morbidity or mortality due to coronavirus disease 2019 (COVID-19). This study aims investigate relationship obesity, as defined by body mass index (BMI), and COVID-19. Data from 5628 confirmed COVID-19 patients were collected Centers for Disease Control Prevention Korea. The hazard ratios (HRs) in BMI groups analyzed using Cox proportional model adjusted covariates. odds (ORs) diabetes logistic regression same Both...

Despite the numerous studies on coronavirus disease 2019 (COVID-19), data regarding impact of pre-existing diagnoses Alzheimer's (AD) and Parkinson's (PD) susceptibility to outcome COVID-19 are limited. We aimed determine whether patients with AD/PD had a higher likelihood contracting experiencing worse outcomes.Data from confirmed (n = 8,070) January June 2020 control participants 121,050) who were randomly selected match basis age sex extracted Korean National Health Insurance Database....

Background: The aim of this study was to investigate the association between temporomandibular disorder (TMD) and migraine through a longitudinal follow-up using population data from national health screening cohort. Methods: This cohort used Korean National Health Insurance Service-Health Screening Cohort 2002 2015. Of 514,866 participants, 3884 TMD patients were matched at 1:4 ratio with 15,536 control participants. Crude models adjusted for obesity, smoking, alcohol consumption, systolic...

Although the effects of coffee consumption and physical exercise on risk cancer have been suggested, their interactions not investigated. The present cross-sectional study aimed to investigate correlation with cancer. Participants ≥40 years old in Korean Genome Epidemiology Study 2004-2016 were included (n = 162,220). Histories gastric cancer, hepatic colon breast uterine cervix lung thyroid prostate bladder analyzed according groups using logistic regression models. odds among individuals...

(1) Background: The purpose of the study was to evaluate associations between physical activity (PA), sunshine duration (SD) and occurrence osteoporosis according lifestyle status. (2) Methods: Data from Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC) collected 2009 2015 were used. Osteoporosis (

Abstract The objective of this study was to evaluate the influence exposure meteorological conditions, including air pollution, on thyroid cancer. A nested case–control conducted utilizing 4632 patients with cancer and 18,528 control subjects who were matched at a 1:4 ratio by age group, sex, income, region residence. Korean National Health Insurance Service-Health Screening Cohort data from 2002 2015 used. Odds ratios (ORs) 95% confidence intervals (CIs) calculated for correlated pollution...

This study aimed to investigate the change in incidence and variance of otorhinolaryngologic diseases during coronavirus disease 19 (COVID-19) pandemic. The entire Korean population (~50 million) was evaluated for monthly 11 common upper respiratory infection (URI), influenza, acute tonsillitis, peritonsillar abscess, retropharyngeal parapharyngeal laryngitis bronchitis, stomatitis related lesions, sinusitis, rhinitis, otitis media, dizziness from January 2018 through March 2021 using...