Resistin is an adipocyte-derived peptide that might play a role in obesity and insulin resistance. However, its humans largely unclear. Although many studies have measured the expression of human resistin tissues, circulating concentrations relation to metabolic parameters are unknown. We developed ELISA for plasma aged individuals with or without type 2 diabetes mellitus. To validate results our subjects, adiponectin were also determined, which higher nondiabetic subjects than diabetic...

Esophageal cancer constitutes a global public health challenge. However, South Korean population-specific information on the association of lifestyle (smoking, alcohol consumption, and obesity status) with esophageal risk is sparse. This nested case–control study analyzed national screening cohort data (2002–2019) 1114 patients 4456 controls (1:4 propensity-score matched for sex, age, income, residential region). Conditional unconditional logistic regression analyses, after adjustment...

Proton pump inhibitors (PPIs) are widely used for acid-related gastrointestinal disorders, but their potential association with lung cancer risk and mortality remains underexplored debated. This study sought to investigate the between PPI use likelihood mortality, focusing on impact of exposure history duration. utilized data from 6795 patients, 27,180 matched controls, 4257 deceased 2538 surviving patients Korean National Health Insurance Service's Screening Cohort (2002-2019). Propensity...

Although safety concerns regarding proton pump inhibitor (PPI)/H2-receptor antagonists (H2RA) in the incident esophageal cancer have been raised, Asian-based report is unclear. We investigated estimated likelihood of cancer—its mortality depending on prior history PPI/H2RA use—and gastroesophageal reflux disease (GERD) Koreans. Using Korean National Health Insurance Service-Health Screening Cohort data (2002−2015), a case−control study was retrospectively conducted, including 811 patients...

Background: Radiomics is a non-invasive and cost-effective method for predicting the biological characteristics of tumors. In this study, we explored association between radiomic features derived from magnetic resonance imaging (MRI) genetic alterations in patients with breast cancer. Methods: We reviewed electronic medical records cancer available targeted next-generation sequencing data August 2018 May 2021. Substraction T1-weighted sequences was utilized. The tumor area on MRI segmented...

At present, many surgeons prefer axillary artery cannulation because it facilitates antegrade cerebral perfusion and may diminish the risk of embolization. However, has not been established as a routine procedure there is controversy about its clinical advantage.We examined 111 patients diagnosed with acute type A aortic dissection between January 2000 December 2009. The right was cannulated in 58 (group A) femoral 53 F). postoperative outcomes were retrospectively reviewed compared two...

ALK-positive (ALK+) lung adenocarcinoma usually shows a more advanced-staged disease with frequent nodal metastasis and highly aggressive outcomes compared EGFR-mutated cancers. The aim of this study was to investigate the expression profiles several mucins in ALK + cancers gain insight into relationship between biological nature role mucins. We examined immunohistochemical MUC1, MUC2, MUC5AC, MUC6 19 42 were found occur younger patients characterized by solid-predominant histologic subtype...

Abstract Background Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, involved in the pathogenesis of ESCC and thus a potential target. PIK3CA , KRAS BRAF mutations, microsatellite instability (MSI) caused by deficient mismatch repair (dMMR), human papillomavirus (HPV) can potentially upregulate PD-L1 expression, might contribute to clinical outcome patients ESCC....

Limited data are available on the diagnostic utility of circulating tumor DNA (ctDNA) in early-stage thyroid cancers for BRAF, KRAS, NRAS, and TERT promoter mutations, which known detectable markers cancers. Here, we analyzed above driver mutations ctDNA matched neoplastic tissues from patients with order to investigate distinguishing other mimicking lesions healthy individuals. In total, 73 tissue plasma samples [thyroid (n = 62), benign disorders 8), parathyroid 3)] 54 individuals (as...

Objectives The prognosis of IDDM is mainly dependent on complicated diabetic nephropathy which probably determined by both metabolic abnormalities and genetic predisposition. Angiotensin I converting enzyme (ACE) regulates systemic renal circulations through angiotensin II formation kinins metabolism. insertion(I)/deletion(D) polymorphism in intron 16 ACE gene strongly associated with levels, subjects homozygote for deletion (genotype DD) have the highest plasma values. Recently, it was...

Abstract Background Therapeutic extracorporeal membrane oxygenation (ECMO) is a challenging procedure in patients who have experienced severe trauma. Particularly, with traumatic lung injury and posttraumatic acute respiratory distress syndrome (ARDS) high risk of bleeding during this procedure. This study aimed to determine the safety feasibility ECMO ARDS. Methods We retrospectively reviewed medical records investigated clinical outcomes 42 ARDS, among whom near-drowning (42.9%) was most...

Abstract Background Recurrent laryngeal nerve paralysis (RLNP) is a common complication after esophagectomy which can cause severe pulmonary complications. However, bilateral RLNP has been rarely reported in patients. The objective of our study to investigate the clinical significance patients who had following esophagectomy. Methods We retrospectively reviewed underwent at single center from 1994 2018. Among these, with vocal cord were included this study. Results A total 3217 and 400...

Hong Kyu Lee, M.D., Kun Il Kim, Won Yong Hyoung Soo Hee Sung and Woo Cho, M.D.. Korean J Thorac Cardiovasc Surg 2012;45:257-9. https://doi.org/10.5090/kjtcs.2012.45.4.257

Extracorporeal membrane oxygenation (ECMO) can be used in patients with refractory cardiogenic shock or respiratory failure. In South Korea, the need for transporting ECMO is increasing. Nonetheless, information on urgent transportation and its outcomes scant.In this retrospective review of 5 years experience at a single center, clinical transported were compared those in-hospital patients. The effects relationship between insertion-departure time survival also analyzed.There 323 cases...

Although there is no obvious recommendation for the management of pneumothorax recurrence after surgery, chemical pleurodesis with tetracycline has been applied as a significant treatment approach. The objective this study was to evaluate effectiveness postoperative primary spontaneous (PSP).We retrospectively analyzed patients who underwent video-assisted thoracic surgery (VATS) therapy PSP at Hallym University Sacred Heart Hospital from January 2010 December 2016. Patients had ipsilateral...

Coronavirus disease 2019 (COVID-19) can lead to acute respiratory failure, which frequently necessitates invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO). However, the limited availability of ECMO resources poses challenges patient selection associated decision-making. Consequently, this retrospective single-center study was undertaken evaluate characteristics clinical outcomes patients with COVID-19 receiving ECMO.

Extracorporeal membrane oxygenation (ECMO) is an intervention for severe heart and lung failure; however, it poses the risk of complications, including gastrointestinal bleeding (GIB). Comprehensive analyses GIB in patients undergoing ECMO are limited, its impact on clinical outcomes remains unclear.

There is limited evidence regarding the impact of coronavirus disease 2019 (COVID-19) pandemic on epidemiology thoracic and cardiovascular diseases. This study aimed to investigate changes in medical visits for these conditions during COVID-19 pandemic.

The aim of this study was to evaluate the short-term and long-term results surgical treatment for native valve endocarditis (NVE) investigate risk factors associated with mortality.Data including patients' characteristics, operative findings, postoperative results, survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital.A total 29 patients underwent surgery NVE (affecting mitral in 20 aortic 9) between 2003 2017. During follow-up period (median, 46.9...

We aimed to investigate the characteristics of primary spontaneous pneumothorax (PSP) in adolescents and analyze relationship between occurrence PSP air pollutants.Data pertaining age, sex, body mass index, smoking status, initial volume, presence bullae, treatment methods, city residence were retrospectively obtained from January 2010 December 2014. investigated association short-term exposure pollutants (SO2, NO2, O3, CO, PM10) using a case-crossover design with conditional logistic...

Background:The aims of the study were to determine accuracy fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting pulmonary metastasis through video-assisted thoracoscopic surgery (VATS), a technique that allows excisional biopsy small nodules patients with known malignancies.Materials and Methods: Between October 2007 April 2010, 28 malignancies underwent VATS biopsies.All follow-up for previously treated malignancy.The included following: colorectum (9), breast (6), head...