A5047027037- Chronic Obstructive Pulmonary Disease (COPD) Research
- Plant Physiology and Cultivation Studies
- Plant Pathogens and Fungal Diseases
- Respiratory Support and Mechanisms
- Plant Disease Management Techniques
- Palliative Care and End-of-Life Issues
- Cystic Fibrosis Research Advances
- Chronic Disease Management Strategies
- Insect and Pesticide Research
- Insect-Plant Interactions and Control
- Nuts composition and effects
- Plant Micronutrient Interactions and Effects
- Nematode management and characterization studies
- Heart Rate Variability and Autonomic Control
- Dysphagia Assessment and Management
- Forest Insect Ecology and Management
- Neuroscience of respiration and sleep
- Respiratory and Cough-Related Research
- Entomopathogenic Microorganisms in Pest Control
- Family and Patient Care in Intensive Care Units
- Asthma and respiratory diseases
- Banana Cultivation and Research
- Plant Disease Resistance and Genetics
- Fungal Plant Pathogen Control
- Obstructive Sleep Apnea Research
King's College Hospital
2014-2024
King's College London
2015-2024
Cicely Saunders International
2014-2024
King's College Hospital NHS Foundation Trust
2015-2024
University of Cambridge
2024
Guy's and St Thomas' NHS Foundation Trust
2021
King's College School
2013-2018
Sheffield Children's NHS Foundation Trust
2015
Chartered Society of Physiotherapy
2015
Sheffield Teaching Hospitals NHS Foundation Trust
2015
Background Breathlessness is a common and distressing symptom, which increases in many diseases as they progress diffi cult to manage.We assessed the eff ectiveness of early palliative care integrated with respiratory services for patients advanced disease refractory breathlessness.Methods In this single-blind randomised trial, we enrolled consecutive adults breathlessness from three large teaching hospitals via general practitioners South London.We randomly allocated (1:1) receive either...
Respiratory symptoms are ubiquitous and impair health-related quality of life in people with respiratory disease. This European Society (ERS) task force aimed to provide recommendations for symptomatic treatment serious illness. The ERS comprised 16 members, including representatives illness informal caregivers. Seven questions were formulated, six the PICO (Population, Intervention, Comparison, Outcome) format, which addressed full systematic reviews evidence assessed using GRADE (Grading...
The aim of the present study was to use diaphragm electromyogram (EMG(di)) compare levels neural respiratory drive (NRD) in a cohort healthy subjects and chronic obstructive pulmonary disease (COPD) patients, investigate relationship between NRD function COPD. EMG(di) recorded at rest normalised peak during maximum inspiratory manoeuvres (EMG(di) % max) 100 30 patients with COPD, using multipair oesophageal electrode. amplitude compound muscle action potential (CMAP(di,MS)) 64 subjects....
The existence of nickel (Ni) deficiency is becoming increasingly apparent in crops, especially for ureide-transporting woody perennials, but its physiological role poorly understood. We evaluated the concentrations ureides, amino acids, and organic acids photosynthetic foliar tissue from Ni-sufficient (Ni-S) versus Ni-deficient (Ni-D) pecan (Carya illinoinensis [Wangenh.] K. Koch). Foliage Ni-D seedlings exhibited metabolic disruption nitrogen metabolism via ureide catabolism, acid...
<h3>Background</h3> Neural respiratory drive (NRD) measured from the diaphragm electromyogram (EMGdi) reflects load/capacity balance of muscle pump and is a marker lung disease severity. EMGdi measurement invasive, but recording EMG parasternal intercostal muscles using surface electrodes (sEMGpara) could provide non-invasive method assessing NRD <h3>Objectives</h3> To test hypothesis that by sEMGpara correlates with EMGdi, to an index severity in cystic fibrosis (CF) relate exercise-induced...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and identification of iturins as antifungal peptides in biological control peach brown rot with Bacillus subtilisRichard C. Gueldner, Charles Reilly, P. Lawrence Pusey, Catherine E. Costello, Richard F. Arrendale, H. Cox, David S. Himmelsbach, Gene Crumley, Horace G. CutlerCite this: J. Agric. Food Chem. 1988, 36, 2, 366–370Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March...
<h3>Background</h3> Acute exacerbations of chronic obstructive pulmonary disease have a significant negative impact on both patients and healthcare systems. Currently, there are no physiological biomarkers that effectively monitor clinical change or predict respiratory readmission. impose in the muscle load-capacity-drive relationship. It was hypothesised lack fall neural drive would identify at risk treatment failure early hospital <h3>Methods</h3> An observational study performed two UK...
Strategies in many countries have sought to improve palliative care and reduce hospital deaths for non-cancer patients, but their effects are not evaluated. We aimed determine the trends factors associated with dying two common progressive respiratory diseases, impact of a national end life (EoLC) strategy hospital. This population-based observational study linked death registration data people England from chronic obstructive pulmonary disease (COPD) or interstitial diseases (IPD). plotted...
Background: Refractory breathlessness in advanced chronic disease leads to high levels of disability, anxiety and social isolation. These result health-resource use, although this is not quantified. Aims: To measure the cost care for patients with refractory identify factors associated costs. Design: A cross-sectional secondary analysis data from a randomised controlled trial. Setting/participants: Patients recruited three National Health Service hospitals via general practitioners South...
Mouse-ear (ME) is a potentially severe anomalous growth disorder affecting pecan [ Carya illinoinensis (Wangenh.) K. Koch] trees. It especially in second generation sites throughout much of the Gulf Coast Coastal Plain southeastern U.S., but can also occur potted nursery Orchard and greenhouse studies on trees treated with either Cu or Ni indicated that foliar applied corrects ME. ME symptoms were prevented, both orchard trees, by single mid-October spray (nickel sulfate), whereas nontreated...
Understanding the effects of respiratory load on neural drive and pattern are key to understanding regulation compensation in disease. The aim study was examine compare recruitment diaphragm parasternal intercostal muscles when system loaded using two methods. Twelve subjects performed incremental inspiratory threshold loading up 50% their maximal pressure, 10 underwent incremental, steady-state hypercapnia a inspired CO2 5%. diaphragmatic electromyogram (EMGdi) measured multipair...
This communication reports that the mouse-ear or little-leaf disorder and associated replant disease of pecan [Carya illinoinensis (Wangenh.) K. Koch] is a Ni deficiency cured by timely foliar application (at 100 mg L-1); thus documenting first known example in orchard crops. Deficiency inducible on soils with adequate content a) excessively high soil Zn, Cu, Mn, Fe, Ca, Mg; b) root damage root-knot nematodes; c) dry cool at time bud break. Symptoms deficiency, but varying severity include...
Abstract The heavy levels of sooty mold commonly present on pecan [ Carya illinoensis (Wangenh.) C. Koch] foliage in the autumn prompted an evaluation its influence net photosynthesis (Pn) leaves. Extra were observed to block light penetration leaf surface by up 98%. Heavy suppressed leaflet Pn 70% with suppression due a blockage photosynthetically active radiation (PAR). An 4°C increase abaxial temperature may also contribute this suppression. results indicate possible need introduce...
Breathlessness is a common and distressing symptom affecting many patients with advanced disease both from malignant non-malignant origin. A combination of pharmacological non-pharmacological measures necessary to treat this successfully. services in various compositions aim provide comprehensive care for their carers by multiprofessional team but effectiveness cost-effectiveness have not yet been proven. The Support Service (BSS) newly created interdisciplinary outpatient service at large...
Three species of aphids attack pecan foliage, Carya illinoensis (Wang.) K. Koch, and cause economic damage. We tested a kaolin-based particle film against one these aphid species, black aphid, Melanocallis caryaefoliae (Davis). Effect on host selection, adult mortality, production nymphs by M. was seedling pecans in the laboratory. Fewer adults selected treated foliage compared with untreated foliage. A higher percentage that did select were recovered from upper leaf surfaces leaves....
Background: We developed a new single point of access to integrated palliative care, respiratory medicine and physiotherapy: the breathlessness support service for patients with advanced disease refractory breathlessness. This study aimed describe patients’ experiences identify aspects valued. Design: attempted survey all who had attended completed 6-week intervention by sending them postal questionnaire self-complete covering experience, composition, effectiveness BSS about participation in...
Neural respiratory drive, quantified by the parasternal intercostal muscle electromyogram (EMGpara), provides a sensitive measure of system load-capacity balance. Reference values for EMGpara-based measures are lacking and influence individual anthropometric characteristics is not known. EMGpara conventionally expressed as percentage that obtained during maximal inspiratory effort (EMGpara%max), leading to difficulty in applying technique subjects unable reliably perform such manoeuvres. To...
In February 2025, the first confirmed case of monkeypox virus (MPXV) clade Ia infection outside Africa was identified in a traveller returning to Ireland from Democratic Republic Congo (DRC). We report clinical, laboratory, and epidemiologic features this case, including stable disease course absence secondary transmission. also present phylogenetic analysis APOBEC3-associated mutation profiling that placed obtained patient an evolving cluster MPXV infections Kinshasa, DRC, likely driven by...
Journal Article Behavior of Solenopsis invicta (Hymenoptera: Formicidae) in Pecan Orchards Get access W. L. Tedders, Tedders 1 Agricultural Research Service, U.S. Department Agriculture 1Southeastern Fruit and Tree Nut Laboratory, USDA-ARS, P.O. Box 87, Byron, Ga. 31008. Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Reilly, Reilly 2 2Pest Management Unit, DG, College Station, Tex. 77841. B. Wood, Wood R. K. Morrison, Morrison S. Lofgren 3 3Imported Fire...
Abstract Our objective was to determine the suppressive abilities of bacterial metabolites derived from Xenorhabdus and Photorhabdus spp. on Glomerella cingulata, Phomopsis sp., Phytophthora cactorum, Fusicladosporium effusum, which are fungal or oomycete pathogens pecan, Monilinia fructicola, a pathogen peach. In first set in vitro assays, when were compared based initial cell count, X. bovienii (SN) generally exhibited greatest suppression phytopathogens sp. (355) least with luminescens...
Oxytetracycline (OTC), a member of the tetracycline antibiotics, is used as foliar spray to control Xanthomonas arboricola pv. pruni on stone fruits and Erwinia amylovora pome fruits. We studied dynamics OTC residues attached peach (Prunus persica) leaves treated with 300 ppm active ingredient an agricultural in relation temperature, natural sunlight, simulated rain. further evaluated potential three ultraviolet (UV) protectants (lignin, titanium dioxide, oxybenzone) one sticker-extender (Nu...
The parasternal intercostal muscle electromyogram (sEMGpara) is a measure of neural respiratory drive and reflects lung disease severity in stable cystic fibrosis (CF). aim the study was to sEMGpara acute infective exacerbations CF compare changes with those conventional function measures. 12 patients admitted hospital an chest infection were studied. There significant reduction mean ± SD (ΔsEMGpara -38 19%, p<0.001) between admission discharge. Spirometery also improved significantly from...