A5056567386- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Blood transfusion and management
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Organ Transplantation Techniques and Outcomes
- Congenital Heart Disease Studies
- Central Venous Catheters and Hemodialysis
- COVID-19 Clinical Research Studies
- Trauma Management and Diagnosis
Johns Hopkins Medicine
2021-2025
Johns Hopkins University
2021-2025
Johns Hopkins Hospital
2023-2025
English Heritage
2015-2023
Charlottesville Medical Research
2023
New York Proton Center
2023
Digital Scholar (United States)
2023
University of Maryland, Baltimore
2012-2021
University of Maryland Medical Center
2012-2021
Duke University
2008-2021
In a randomized trial comparing mitral-valve repair with replacement in patients severe ischemic mitral regurgitation, we found no significant difference the left ventricular end-systolic volume index (LVESVI), survival, or adverse events at 1 year after surgery. However, group had significantly more recurrences of moderate regurgitation. We now report 2-year outcomes this trial.We randomly assigned 251 to replacement. Patients were followed for 2 years, and clinical echocardiographic...
Ischemic mitral regurgitation is associated with a substantial risk of death. Practice guidelines recommend surgery for patients severe form this condition but acknowledge that the supporting evidence repair or replacement limited.
Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling.To develop a simple bedside algorithm estimating patients' probability after cardiac surgery, we evaluated data 449,524 patients undergoing coronary artery bypass grafting (CABG) and/or valve surgery enrolled in >600 hospitals participating the Society Thoracic Surgeons National Database (2002-2004). Logistic regression was used to identify major...
Perioperative blood transfusions are costly and have safety concerns. As a result, there been multiple initiatives to reduce transfusion use. However, the degree which perioperative rates vary among hospitals is unknown.To assess hospital-level variation in use of allogeneic red cell (RBC), fresh-frozen plasma, platelet patients undergoing coronary artery bypass graft (CABG) surgery.An observational cohort 102,470 primary isolated CABG surgery with cardiopulmonary during calendar year 2008...
In a trial comparing coronary-artery bypass grafting (CABG) alone with CABG plus mitral-valve repair in patients moderate ischemic mitral regurgitation, we found no significant difference the left ventricular end-systolic volume index (LVESVI) or survival after 1 year. Concomitant was associated reduced prevalence of severe but had more adverse events. We now report 2-year outcomes.We randomly assigned 301 to undergo either combined procedure. Patients were followed for 2 years clinical and...
Ischemic mitral regurgitation is associated with increased mortality and morbidity. For surgical patients moderate regurgitation, the benefits of adding mitral-valve repair to coronary-artery bypass grafting (CABG) are uncertain.
Atrial fibrillation after cardiac surgery is associated with increased rates of death, complications, and hospitalizations. In patients postoperative atrial who are in stable condition, the best initial treatment strategy--heart-rate control or rhythm control--remains controversial.Patients new-onset were randomly assigned to undergo either rate control. The primary end point was total number days hospitalization within 60 randomization, as assessed by Wilcoxon rank-sum test.Postoperative...
Background— Few studies have examined the procedural volume–outcome relationship for heart valve surgery. None process of care factors that may be mediators this association. Methods and Results— This was a retrospective review outcomes 13 614 patients having elective surgery mitral regurgitation between 2000 2003 in 575 North American centers participating Society Thoracic Surgeons National Cardiac Database. Hospital annual volume varied widely from 22 cases per year lowest-volume quartile...
Tricuspid regurgitation is common in patients with severe degenerative mitral regurgitation. However, the evidence base insufficient to inform a decision about whether perform tricuspid-valve repair during mitral-valve surgery who have moderate tricuspid or less-than-moderate annular dilatation. We randomly assigned 401 were undergoing for receive procedure without annuloplasty (TA). The primary 2-year end point was composite of reoperation regurgitation, progression by two grades from...
Background— Reoperation for bleeding represents an important complication in patients undergoing coronary artery bypass surgery (CABG). Yet, few studies have characterized risk factors and patient outcomes of this event. Methods Results— We evaluated 528 686 CABG at >800 hospitals the Society Thoracic Surgeons National Cardiac Database (2004 to 2007). Clinical features in-hospital were with without reoperation after CABG. Logistic regression was used identify predictors event estimate...