A5086195248- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Frailty in Older Adults
- Nutrition and Health in Aging
- Immune Cell Function and Interaction
- Renal Transplantation Outcomes and Treatments
- Birth, Development, and Health
- Esophageal Cancer Research and Treatment
- Pleural and Pulmonary Diseases
- Animal Virus Infections Studies
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Ovarian function and disorders
- Alcohol Consumption and Health Effects
- Gastric Cancer Management and Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Treatments and Mutations
University of California, San Francisco
2019-2024
Clinical Research Institute
2006-2009
Duke University
2007-2009
Baptist Medical Center Jacksonville
2009
Durham University
2007-2009
Brigham and Women's Hospital
2009
University of Maryland, Baltimore
2006-2008
Duke University Hospital
2008
Duke Medical Center
2008
University of Florida
2006-2008
Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling.To develop a simple bedside algorithm estimating patients' probability after cardiac surgery, we evaluated data 449,524 patients undergoing coronary artery bypass grafting (CABG) and/or valve surgery enrolled in >600 hospitals participating the Society Thoracic Surgeons National Database (2002-2004). Logistic regression was used to identify major...
Use of an internal mammary artery (IMA) is a well-recognized, nationally endorsed quality indicator for evaluating the process operative care coronary bypass graft surgery. An objective assessment current status IMA use has not been systematically performed.This cross-sectional observational study analyzed data on 541 368 surgery procedures reported by 745 hospitals in Society Thoracic Surgeons National Cardiac Database from 2002 through 2005. We assessed use, association hospital volume and...
United Network for Organ Sharing (UNOS) recently implemented a national policy granting priority listing liver transplantation (LT) in patients who achieved down-staging of hepatocellular carcinoma (HCC) to Milan criteria. We aimed evaluate the experience on by comparing two groups with (1) tumor burden meeting UNOS (UNOS-DS) inclusion criteria and (2) "all-comers" (AC-DS) initial beyond UNOS-DS versus always within Milan.
The impact of hepatorenal function on plasma biomarkers neuropathology is unknown. Herein, we measured several in patients with cirrhosis.
Previous studies showed 75% mortality before hospital discharge in patients with a ventricular assist device (VAD) placed for post-cardiac surgery shock. We examined large national clinical database to assess trends the incidence of shock requiring VAD implantation, survival rates, and risk factors mortality.We identified undergoing procedure after cardiac at US hospitals participating Society Thoracic Surgeons' National Cardiac Database during years 1995 2004. Baseline characteristics...
Background— There exist few studies that characterize contemporary clinical features and outcomes or risk factors for operative mortality in cardiogenic shock (CS) patients undergoing coronary artery bypass grafting (CABG). Methods Results— We evaluated data of 708 593 with without CS CABG enrolled the Society Thoracic Surgeons National Cardiac Database (2002–2005). Clinical, angiographic, in-hospital were CS. Logistic regression was used to identify predictors estimate weights an additive...
Abstract Background and Aims Autoimmune hepatitis (AIH) disproportionately affects young women, which may have implications in pregnancy. However, data on pregnancy outcomes women with AIH are limited. Approach Results Using weighted discharge from the United States National Inpatient Sample 2012 to 2016, we evaluated pregnancies after 20 weeks gestation compared other chronic liver diseases (CLD) or no CLD The association of maternal perinatal was assessed by logistic regression. Among...
Summary Background Chronic hepatitis B infection is an important contributor to mortality in the United States, yet impact of available and effective oral antivirals on among infected individuals unknown. Aims To compare risks predictors a recent time period between those with chronic, prior no infection. Methods This population‐based cohort study National Health Nutrition Examination Surveys participants 1999 2014 linked Death Index data. Adults aged 20 years or older serologic testing were...
Abstract Background & Aims Cirrhosis leads to malnutrition and muscle wasting that manifests as frailty, which may be influenced by cirrhosis aetiology. We aimed characterize the relationship between frailty Methods Included were adults with listed for liver transplantation (LT) at 10 US centrer who underwent ambulatory testing Liver Frailty Index (LFI; ‘frail’ = LFI ≥ 4.4). used logistic regression associate aetiologies competing risk (LT risk) determine associations waitlist mortality...
<h3>Importance</h3> There are well-documented racial/ethnic and socioeconomic disparities in access to health care among patients with hepatocellular carcinoma (HCC); however, there little data on the association of insurance type liver transplant (LT) wait-list outcomes for HCC. <h3>Objective</h3> To examine LT HCC public compared private insurance. <h3>Design, Setting, Participants</h3> This single-center cohort study included 705 adult who had Model End-Stage Liver Disease exceptions were...
Liver transplantation (LT) recipients with hepatocellular carcinoma (HCC) receive a higher proportion of livers from donation after circulatory death (DCD) donors compared non‐HCC etiologies. Nevertheless, data on outcomes in patients HCC receiving DCD grafts are limited. We evaluated the influence post‐LT outcome among patients. identified 7563 United Network for Organ Sharing (UNOS) database who underwent LT Model End‐Stage Disease score exceptions 2012 to 2016, including 567 (7.5%)...
Physical frailty and impaired cognition are common in patients with cirrhosis. can be assessed using performance‐based tests, but the extent to which may impact performance is not well characterized. We relationship between physical enrolled 1,623 ambulatory adult cirrhosis waiting for liver transplantation at 10 sites. Frailty was index (LFI; “frail,” LFI ≥ 4.4). Cognition same visit number connection test (NCT); continuous “impaired cognition” examined primary analysis, longer NCT (more...
Living donor liver transplantation (LDLT) is an attractive option to decrease waitlist dropout, particularly for patients with hepatocellular carcinoma (HCC) who face lengthening waiting times. Using the United Network Organ Sharing (UNOS) national database, trends in LDLT utilization HCC were evaluated, and post-LT outcomes versus deceased (DDLT) compared. From 1998 2018, LT was performed 20,161 including 726 (3.6%) received LDLT. The highest prior 2002 Model End-Stage Liver Disease (MELD)...
Abstract Polycystic ovary syndrome (PCOS) occurs in approximately 10% of all reproductive‐age women, with over 50% these patients having imaging‐confirmed nonalcoholic fatty liver disease (NAFLD). Whether PCOS increases the risk for more clinically relevant disease, such as steatohepatitis (NASH), is unclear. Such findings are to prognosticating progressive growing population young adults NAFLD. Using weighted discharge data from United States National Inpatient Sample 2016 2018, we...
The use of living donor liver transplantation (LDLT) for primary (LT) may quell concerns about allocating deceased organs if the need retransplantation (re-LT) arises because LT did not draw from limited organ pool. However, outcomes re-LT after LDLT are poorly studied. purpose this study was to analyze Adult Living Donor Liver Transplantation Study (A2ALL) data report LDLT, with a focus on long-term survival re-LT.A retrospective review A2ALL collected between 1998 and 2014 performed....
Background. Alcoholic liver disease (ALD) accounts for 15%–30% of transplants performed in the United States and Europe; however, data on living donor transplantation (LDLT) ALD remain sparse. The purpose this study was to examine outcomes following LDLT using from adult-to-adult (A2ALL) study, which represents largest Western experience with LDLT. Methods. A retrospective review A2ALL collected between 1998 2014 performed. Patients were excluded if they received a deceased transplant....