A5064652965- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Urinary Tract Infections Management
- Sex work and related issues
- HIV, Drug Use, Sexual Risk
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Genital Health and Disease
- Gut microbiota and health
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Adolescent Sexual and Reproductive Health
- HIV, TB, and STIs Epidemiology
- HIV/AIDS Research and Interventions
- Urinary and Genital Oncology Studies
- Plant and fungal interactions
- Nuts composition and effects
- Cervical Cancer and HPV Research
- Trypanosoma species research and implications
- Streptococcal Infections and Treatments
- Legionella and Acanthamoeba research
- Reproductive Health and Contraception
- Sexuality, Behavior, and Technology
- Neonatal and Maternal Infections
University of Buenos Aires
2016-2025
European Society of Clinical Microbiology and Infectious Diseases
2025
Hospital de Clínicas "José de San Martín"
2010-2022
Hospital General Universitario Gregorio Marañón
2019
Hospital Fernández
2019
Instituto de Química y Fisicoquímica Biológicas
2018
Universidad Nacional de Córdoba
2006
Policlinico S.Orsola-Malpighi
1999
University of Bologna
1999
Chlamydia trachomatis is the world's most prevalent bacterial sexually transmitted infection and leading infectious cause of blindness, yet it one least understood human pathogens, in part due to difficulties vitro culturing lack available tools for genetic manipulation. Genome sequencing has reinvigorated this field, shedding light on contemporary history pathogen. Here, we analyze 563 full genomes, 455 which are novel, show that species comprises two phases, conclude currently circulating...
Graphical Abstract Using target enrichment, RNA baits designed around a panel of bacterial sexually transmitted infections were used to fish DNA from the clinical sample, leading complete genome sequences.
Due to the scarce data on prevalence of sexually transmitted infections (STIs) among male-to-female trans-sex workers (TSW) and male sex (MSW) in Argentina, present study aimed estimate incidence human immunodeficiency virus (HIV), HIV, hepatitis B (HBV), C (HCV), Treponema pallidum. Human papillomavirus (HPV) Chlamydia trachomatis were tested TSW.Two hundred seventy-three TSW 114 MSW recruited by nongovernmental organizations. HIV was estimated STARHS (serologic testing algorithm for recent...
Background Violence against female sex workers (FSWs) has been increasingly reported as an important determinant of HIV infection risk. This study explores the frequency different violent experiences (sexual abuse, rejection, beating and imprisonment) among FSWs in Argentina its association with condom use T. pallidum prevalence. Methods A convenience sample 1255 was included a cross-sectional conducted between October 2006 November 2009. Results Sexual abuse by 24.1% (219/907) women. total...
Since the Lymphogranuloma venereum (LGV) outbreak was first described in Buenos Aires 2017, detected strains presented peculiar characteristics. Our goal to increase understanding of involved LGV Argentina. We characterized ompA gene sequences, using Sanger sequencing, 88 from 239 symptomatic patients enrolled between 2017 and 2019, selected 20 C. trachomatis for further characterization Multilocus Sequence Typing (MLST). Following analysis strains, we 43% L2b, 31% L1-like, 26% L2. Among 38...
OBJECTIVES AND WORKING HYPOTHESIS: To evaluate the prevalence of respiratory viruses Mycoplasma pneumoniae and Chlamydophila gain insight into their seasonal circulation pattern in children with acute asthma exacerbations a temperate southern hemisphere region.Patients hospitalized between 3 months 16 years age were included 1-year prospective, observational, cross-sectional study. Respiratory secretions collected presence different atypical bacteria analyzed by immunofluorescence polymerase...
The in-vitro activity of moxifloxacin, a new 8-methoxyquinolone, was compared with minocycline and azithromycin against 40 strains Chlamydia trachomatis, pneumoniae psittaci. Both the MIC MBC moxifloxacin ranged from 0.03 to 0.125 mg/L. MICs 0.015 0.06 mg/L MBCs between 0.25 0.5 values were same as in 32 (80%) tested, whereas those two four times higher than their MICs. These data confirm previously obtained indicating that quinolones kill chlamydial at concentrations equivalent
Background The aim of this study was to estimate the prevalence HIV and other STIs, among MSM from Buenos Aires (2007–2009). Methods Responding Driven Sampling used for recruitment MSM. Participants completed a structured web-based survey provided biological samples. Results A total 496 were studied HIV, HBV, HCV, T pallidum infections. Chlamydia HPV diagnoses only performed in 98 109 participants, respectively. Prevalence 17.3%, HBV 22.9%, HCV 7.5%, 20.5%, 83.5%, C trachomatis 1.7%. In year...
A total of 54 clinical samples, including genital lesion swabs, whole blood and cerebrospinal fluid from patients diagnosed with syphilis were collected in 2006 2013 Buenos Aires, Argentina. Treponemal DNA was detected 43 the analyzed samples (79.6%) further using Sequencing-based molecular typing (SBMT) Enhanced CDC-typing (ECDCT). By SBMT, 10 different Treponema pallidum subsp. (TPA) genotypes found, which six related to TPA SS14 strain, four Nichols strain. The 23S rRNA gene amplified...
Chlamydia trachomatis infections are the most prevalent sexually transmitted bacterial in world. There is scarce data available referring to distribution of C. genotypes Argentina. The aim this study was identify circulating metropolitan area Buenos Aires (Argentina) associated with ophthalmia neonatorum and genital infections.From 2001 2006, 199 positive samples for infection from symptomatic adult patients neonates two public hospitals were studied. determined by PCR-RFLP an ompA...
Graphical Abstract We describe a new lineage of Chlamydia trachomatis lymphogranuloma venereum identified in Argentina, carrying ompA -genotype L4. also present further diversification the globally circulating L2b lineage.
To study the occurrence of Chlamydia spp. and their genetic diversity, we analysed 793 cloacal swabs from 12 avian orders, including 76 genera, obtained 80 species asymptomatic wild captive birds that were examined with conventional nested polymerase chain reaction quantitative reaction. not detected in birds; however, four (Chlamydia psittaci, pecorum, pneumoniae gallinacea) identified among (Passeriformes, n = 20; Psittaciformes, 15; Rheiformes, 8; Falconiformes 2; Piciformes Anseriformes...
Objective: Ocular infection in neonatology is a permanent and important health problem.To improve primary attention, prevention, control, the study of potential bacterial etiology all consecutive cases conjunctivitis was incorporated as regular procedure care from July 1995 to December 1998.Materials Methods: Prof. A. Posadas Hospital (Great Buenos Aires) has an average 4294 births per year.This report analyzes results obtained 332 infants (age range, O-30 d) with conjunctivitis.Clinical...
OBJETIVO: Hay un aumento significativo de pacientes con Secreción Genital Femenina, en el Sector Público del gran Buenos Aires. Fue necesario actualizar la prevalencia los microorganismos asociados a efectos revisar apoyo laboratorio y ajustar las medidas prevención control. MÉTODOS: Se incorporan este estudio, totalidad casos atendidos (1997-1998): 84 adolescentes (15 19 años) 784 adultas (20 60 sintomáticas. El protocolo incluye (secreción vaginal endocervical) detección Neisseria...
Rates of bacterial sexually transmitted infections (STIs) are rising and accessing their genomes provides information on strain evolution, circulating strains, encoded antimicrobial resistance (AMR). Notable pathogens include Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) Treponema pallidum (TP), globally the most common STIs. Mycoplasma genitalium (MG) is also a STI which concern due to AMR development. These bacteria fastidious or hard culture, standard sampling methods lyse...
Chlamydia trachomatis is one of the most common sexually transmitted infections worldwide. Based on sequence variation in ompA gene encoding major outer membrane protein, genotyping scheme distinguishes 17 recognized genotypes, i.e. A, B, Ba, C, D, Da, E, F, G, H, I, Ia, J, K, L1, L2, and L3. Genotyping an important tool for epidemiological tracking C. infections, including revelation transmission pathways association with tissue tropism pathogenicity. Moreover, can be useful clinicians to...
ABSTRACT The Clinical and Laboratory Standards Institute (CLSI) proposed, beginning in 2004, the use of cefoxitin disks to predict resistance mediated by mecA gene all species coagulase-negative staphylococci (CoNS). aim this work was evaluate efficiency disk oxacillin-salt agar screening (MHOX) characterize oxacillin CoNS. One hundred seven CoNS isolates from different clinical samples were studied. Detection PCR considered “gold standard.” susceptibility detected diffusion dilution tests,...
The clinical study aim was to investigate whether a tannin-based dietary supplementation could improve the efficacy of standard-of-care treatment hospitalized COVID-19 patients by restoring gut microbiota function. Adverse events and immunomodulation post-tannin were also investigated. A total 124 receiving randomized oral supplement or placebo for 14 days. Longitudinal blood stool samples collected cytokine 16S rDNA microbiome profiling, results compared with 53 healthy controls. Although...
The aim of this study was to evaluate different methods for Trichomonas vaginalis diagnosis during pregnancy in order prevent maternal and perinatal complications. A total 386 vaginal exudates from pregnant women were analyzed. T. investigated by 3 types microscopic examinations direct wet mount with physiologic saline solution, prolonged May-Grunwald Giemsa (MGG) staining, sodium-acetate-formalin (SAF)/methylene blue method. PCR 18S rRNA gene as well culture liquid medium performed....
Background Chlamydia trachomatis (CT) can infect the anorectum producing various signs and symptoms. There is scarce literature regarding differences between LGV non-LGV CT anorectal manifestations. We compare clinical spectrum of infections. Methods Patients over 18 years with presumptive infectious symptoms were examined in two healthcare centres Buenos Aires. The patients studied treated according to current sexually transmitted infection guidelines. Anorectal swabs collected detect...