A5101931836- Peroxisome Proliferator-Activated Receptors
- Autophagy in Disease and Therapy
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Gout, Hyperuricemia, Uric Acid
- Advanced Glycation End Products research
- Mitochondrial Function and Pathology
- Calcium signaling and nucleotide metabolism
- Cardiovascular Function and Risk Factors
- Cholinesterase and Neurodegenerative Diseases
- Free Radicals and Antioxidants
- Neurological Disease Mechanisms and Treatments
- Bioactive Natural Diterpenoids Research
- Plant-based Medicinal Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Crystal structures of chemical compounds
- Adipose Tissue and Metabolism
- Sirtuins and Resveratrol in Medicine
- Synthesis of Organic Compounds
- Flavonoids in Medical Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Metabolism and Genetic Disorders
- Biochemical Acid Research Studies
- Carbohydrate Chemistry and Synthesis
Chengdu University of Traditional Chinese Medicine
2022-2025
Scutellarin (Scu), a flavonoid from herbal Erigeron breviscapus (Vaniot) Hand-Mazz, exerts neuroprotective effects against cerebral ischemia. However, whether the of Scu are related to mitochondrial protection needs further investigation. In this study, we aimed clarify mechanisms HT22 cells injury caused by oxygen-glucose deprivation and reperfusion (OGD/R). Our results proved that significantly reduced overload intracellular reactive oxygen species (cellar ROS) mitochondria (mito-ROS),...
Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental health of patients generates an enormous socio-economic burden. In addition to cardiac myocyte oxidative stress apoptosis, which are considered mechanisms for development HF, alterations in energy metabolism pathological autophagy also contribute abnormalities ultimately HF. Silent information regulator 1 (Sirt1) adenosine monophosphate-activated protein kinase (AMPK) nicotinamide adenine dinucleotide (NAD
The title molecule, C 24 H 20 N 2 O 5 , is composed of two parts, namely, a butterfly-like xanthene moiety and an almost planar isobenzofuran fragment. plane perpendicular to the planes. C−O bond length in five-membered lactone ring 1.487 (5) A, which longer than usual single-bond