A5064016573- Child and Adolescent Psychosocial and Emotional Development
- Adolescent and Pediatric Healthcare
- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Child and Adolescent Health
- Tryptophan and brain disorders
- Child Abuse and Trauma
- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Genetic Associations and Epidemiology
- Psychosomatic Disorders and Their Treatments
- Mental Health Research Topics
- Early Childhood Education and Development
- Homelessness and Social Issues
- Suicide and Self-Harm Studies
- Genetic Syndromes and Imprinting
- Family Support in Illness
- Bipolar Disorder and Treatment
- Stress Responses and Cortisol
- Childhood Cancer Survivors' Quality of Life
- Maternal Mental Health During Pregnancy and Postpartum
- Health disparities and outcomes
- Homicide, Infanticide, and Child Abuse
- Advanced Neuroimaging Techniques and Applications
- Infant Health and Development
UNSW Sydney
2017-2025
Neuroscience Research Australia
2017-2025
Black Dog Institute
2018
Journal Article Cohort Profile Update: The New South Wales Child Development Study (NSW-CDS) – Wave 3 (child age ∼18 years) Get access Melissa J Green, Green School of Clinical Medicine, University Wales, Sydney, NSW, Australia Corresponding author. Discipline Psychiatry and Mental Health, Faculty Medicine UNSW, Level 1, AGSM Building, Botany Street, UNSW NSW 2052, Australia. E-mail: melissa.green@unsw.edu.au Search for other works by this author on: Oxford Academic PubMed Google Scholar...
BackgroundUnpacking molecular perturbations associated with features of schizophrenia is a critical step towards understanding phenotypic heterogeneity in the disorder. Recent epigenome-wide association studies (EWAS) have uncovered pervasive dysregulation DNA methylation schizophrenia, however, clinical disorder which account for large proportion variability remain relatively underexplored.MethodsWe comprehensively analysed patterns cohort 381 individuals from deeply phenotyped Australian...
Abstract Background Elevated levels of pro-inflammatory cytokines are consistently reported in schizophrenia (SZ) and bipolar-I disorder (BD), as well among individuals who have been exposed to childhood trauma. However, higher inflammatory markers these disorders yet be investigated with respect exposure different types Methods Participants were 68 cases a diagnosis schizophrenia/schizoaffective (SZ), 69 psychotic BD 72 healthy controls (HC). Serum interleukin 6 (IL-6), tumour necrosis...
Objectives: Mental health service use among young people is increasing, and small groups within the population disproportionately account for majority of mental use. The aims this study were to identify population-based trajectories across childhood adolescence associated sociodemographic/other risk factors. Methods: between birth 17 years age identified using zero-inflated Poisson latent-class growth mixture modelling, in a New South Wales cohort 9510 children (born 2002 2005) who had at...
Abstract Background The transition from primary to secondary school presents a challenging developmental milestone which often marks decline in academic performance. Social–emotional skills are recognized as fundamental success but longitudinal research is needed determine the extent of their association over this period. Aim This study sought between self‐reported social–emotional competencies students final year (Year 6; age ~11 years) and reading numeracy performance first 7; ~12 years)....
Abstract Background Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, associated brain functions may be affected by exposure psychotic disorders. We aimed identify the influence of trauma-exposure on activation functional connectivity during task. Methods used magnetic resonance imaging examine function within regions-of-interest [left right inferior frontal gyrus (IFG), dorsolateral prefrontal cortex,...
We investigated patterns of service contact for self-harm and suicidal ideation recorded by a range human agencies - including health, police child protection with specific focus on overlap sequences contacts, age first demographic intergenerational characteristics associated different responses to self-harm.
Psychotic disorders are associated with a growing number of recognized environmental exposures. Cumulative exposure to multiple risk factors in childhood may contribute the development different patterns schizotypy evident early life. Hypotheses were that distinct profiles would have differential associations cumulative score factors.We prospectively examined relationship between 19 exposures (which had demonstrated replicated psychosis) measured from prenatal period through age 11 years,...
Abstract Background Childbirth presents an optimal time for identifying high‐risk families to commence intervention that could avert various childhood health and social adversities. Objective We sought establish the minimum set of exposures required accurately predict a range adverse outcomes up age 13 years, from 14 individual familial risk evident at birth. Methods Participants were 72,059 Australian children their parents drawn multi‐register population cohort study (data spanning...
Abstract Background and Hypothesis Schizotypy provides a framework for understanding the developmental nature of psychotic disorders means identifying “at-risk” individuals early in lifespan. However, there is lack prospective longitudinal research examining relationship between schizotypy childhood later other mental disorders. We hypothesized that distinct profiles would be differentially associated with emerging adolescence. Study Design In large population cohort Australian young people...
Objectives: The rate of mental health services provided to children and young people is increasing worldwide, including in Australia. aim this study was describe patterns hospital ambulatory service use among a large population cohort adolescents followed from birth, with consideration variation by age, sex diagnosis. Methods: Characteristics for disorder diagnoses between birth age 17.5 years were ascertained 85,642 (52.0% male) born 2002 2005, ‘Admitted Patients’, ‘Emergency Department’...
Children in out-of-home care (OOHC) are generally at increased risk of health and social adversities compared to their peers. However, the experiences children OOHC not uniform associated indices may vary relation characteristics placements child protection contact. To examine associations between a range contact (e.g., number, type, age placement) with educational underachievement, mental disorder, police (as victim, witness, or person interest) childhood. Participants were Australian drawn...