Hassan Sheikha

ORCID: 0000-0003-2583-3140
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Dental Research and COVID-19
  • SARS-CoV-2 detection and testing
  • Viral Infections and Immunology Research
  • Hepatitis B Virus Studies
  • Otitis Media and Relapsing Polychondritis
  • Vaccine Coverage and Hesitancy
  • Immunodeficiency and Autoimmune Disorders
  • Viral gastroenteritis research and epidemiology
  • Advanced Text Analysis Techniques
  • COVID-19 Impact on Reproduction
  • Inflammasome and immune disorders
  • COVID-19 Clinical Research Studies
  • Cervical Cancer and HPV Research
  • Genetic factors in colorectal cancer
  • Immune Cell Function and Interaction
  • Sentiment Analysis and Opinion Mining

Yale University
2022-2024

Rare immune-mediated cardiac tissue inflammation can occur after vaccination, including SARS-CoV-2 mRNA vaccines. However, the underlying immune cellular and molecular mechanisms driving this pathology remain poorly understood. Here, we investigated a cohort of patients who developed myocarditis and/or pericarditis with elevated troponin, B-type natriuretic peptide, C-reactive protein levels as well imaging abnormalities shortly vaccination. Contrary to early hypotheses, did not demonstrate...

10.1126/sciimmunol.adh3455 article EN cc-by Science Immunology 2023-05-05

The emergence of the B.1.617.2 (Delta) variant SARS-CoV-2 has led to increases in both infections and hospitalizations among adolescents. Little is known about effectiveness BNT162b2 vaccine adolescents general population, as opposed a clinical trial population.To estimate aged 12 18 years.This was matched case-control study (aged 12-18 years) who had results from reverse transcription-polymerase chain reaction (RT-PCR) test. Immunization histories, relevant data, RT-PCR test were obtained...

10.1001/jamanetworkopen.2022.0935 article EN cc-by-nc-nd JAMA Network Open 2022-03-03

While considerable attention was placed on SARS-CoV-2 testing and surveillance programs in the K-12 setting, younger age groups childcare centers were largely overlooked. Childcare facilities are vital to communities, allowing parents/guardians remain at work providing safe environments for both children staff. Therefore, early COVID-19 pandemic (October 2020), we established a PCR-based program facilities, staff with goal of collecting actionable public health data aiding communities...

10.3389/fpubh.2023.1003158 article EN cc-by Frontiers in Public Health 2023-02-03

Abstract Monoclonal antibodies for COVID-19 are authorized in high-risk patients aged ≥12 years, but evidence pediatric is limited. In our cohort of 142 treated at seven hospitals between 12/1/20 and 7/31/21, 9% developed adverse events, 6% were admitted within 30 days, none received ventilatory support or died.

10.1093/jpids/piac124 article EN Journal of the Pediatric Infectious Diseases Society 2023-03-01

Abstract Background While considerable attention was placed on SARS-CoV-2 testing and surveillance programs in the K-12 setting, younger age groups childcare centers were largely overlooked. Childcare facilities are vital to communities, allowing parents/guardians remain at work providing safe environments for both children staff. Therefore, early COVID-19 pandemic, we established a PCR-based program facilities, staff with goal of collecting actionable public health data aiding communities...

10.1101/2022.05.05.22274434 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-05-09
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