A5052272514- Spine and Intervertebral Disc Pathology
- Scoliosis diagnosis and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Pelvic and Acetabular Injuries
- Trauma and Emergency Care Studies
- Management of metastatic bone disease
- Total Knee Arthroplasty Outcomes
- Hip and Femur Fractures
- Glaucoma and retinal disorders
- Anesthesia and Neurotoxicity Research
- Retinal Imaging and Analysis
- Neuroscience and Neuropharmacology Research
- Clinical practice guidelines implementation
- Glioma Diagnosis and Treatment
- Hip disorders and treatments
- Retinal Diseases and Treatments
- Neural dynamics and brain function
- Neurofibromatosis and Schwannoma Cases
- Spinal Hematomas and Complications
- COVID-19 Pandemic Impacts
Massachusetts General Hospital
2023-2025
Harvard University
2023-2025
Yale University
2018-2024
National Institutes of Health
2023
Konrad-Adenauer-Stiftung
2021-2023
Northwestern University
2019-2022
Cornell University
2022
American College of Surgeons
2021
Neurological Surgery
2020
Oxford University Press (United Kingdom)
2020
Numerous polls suggest that COVID-19 is a profoundly partisan issue in the United States. Using geotracking data of 15 million smartphones per day, we found US counties voted for Donald Trump (Republican) over Hillary Clinton (Democrat) 2016 presidential election exhibited 14% less physical distancing between March and May 2020. Partisanship was more strongly associated with than numerous other factors, including counties' cases, population density, median income, racial age demographics....
Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and unresponsiveness, with yet-unknown neuronal mechanisms. Here we report that an awake female rat model recapitulates the behavioral, electroencephalographic, cortical functional magnetic resonance imaging characteristics human absence seizures. Neuronally, feature overall decreased but rhythmic firing neurons in cortex thalamus. Individual thalamic express one four distinct patterns seizure-associated...
Numerous polls suggest that COVID-19 is a profoundly partisan issue in the U.S. Using geotracking data of 15 million smartphones per day, we found counties voted for Donald Trump (Republican) over Hillary Clinton (Democrat) 2016 presidential election exhibited 14% less physical distancing between March and May 2020. Partisanship was more strongly associated with than numerous factors, including counties’ median income, cases, population density, racial age demographics. Contrary to our...
The purpose of this study was to evaluate the impact image processing on quantitative metrics in optical coherence tomography angiography (OCTA) images and conclusions patients with diabetes.This a single center, retrospective cross-sectional study. OCTA imaging Cirrus HD-OCT 5000 AngioPlex diabetes performed. 8 × mm superficial slab underwent 4 different preprocessing methods (none, background subtraction [BGS], foveal avascular zone brightness adjustment, contrast limited adaptive...
To compare the efficacy of a postoperative continuous adductor canal block (cACB) with and without steroid adjuvant to that epidural analgesia (EA). Patients who underwent primary total TKA at single institution between July 2011-November 2017 were included for retrospective analysis. patients stratified into one three approaches: EA, cACB adjuvant, adjuvant. Hospital length stay (LOS), discharge disposition, incidence adverse events, milligram morphine equivalents (MME) requirements...
Autonomous vehicles (AVs) will radically re-shape the health and well-being of people in United States good ways bad. We set out to estimate a reasonable time-to-adoption using cost-effectivenessmodels point at which AVs become reasonably safe affordable for widespread adoption.We used Waymo data (previously, Google Self-Driving Car Project) microsimulation model explore projected costs safety issues today five years from get sense speed consumer adoption were brought market.The private use...
For complex surgery, intraoperative ketamine administration is readily used to reduce post-operative pain. However, there have been a few studies suggesting that may deleterious effects and impact delirium. Therefore, we sought identify the has on outcomes after spinal surgery involving ≥5 level fusions.The medical records of 138 adult (≥18 years old) spine deformity patients undergoing elective, primary fusion (≥5 level) for correction at major academic institution from 2010 2015 were...
Osteosarcoma is the most common primary bone tumor in children, adolescents, and young adults. Second malignancies (SPMs) are a potential serious long-term event that can occur osteosarcoma survivors.The National Cancer Institute's Surveillance, Epidemiology, End Results 18 database was queried for all cases from 2000 through 2015. Standardized incidence ratio (SIR) absolute excess risk (AER) of SPM per 10,000 persons relative to representative population-level data were calculated across...
Abstract Recent work suggests an important role for cortical–subcortical networks in seizure-related loss of consciousness. Temporal lobe seizures disrupt subcortical arousal systems, which may lead to depressed cortical function and Extracellular recordings show ictal neocortical slow waves at about 1 Hz, but it is not known whether these simply represent seizure propagation or alternatively deep sleep-like activity, should include neuronal Up Down states. In this study, using vivo...
Study Design: Retrospective cohort study. Objective: The aim of this study was to determine the impact age has on LOS and discharge disposition following elective ACDF for cervical spondylotic myelopathy (CSM). Methods: A retrospective performed using National Inpatient Sample (NIS) database from 2016 2017. All adult patients >50 years old undergoing CSM were identified ICD-10-CM diagnosis procedural coding system. Patients then stratified by age: 50 64 years-old, 65 79 greater than or...
Introduction: Centers for Medicare & Medicaid Services (CMS) removed total knee arthroplasty (TKA) from the “inpatient-only” list January 1, 2018. The impact of this change on actual hospital length stay (LOS) and patient coding is interest. Methods: Patients undergoing TKA were abstracted 2015 to 2018 National Surgical Quality Improvement Program database. Patient characterization as “inpatient” or “outpatient” LOS assessed. Ordinal categorical data comparisons done with Pearson...