A5100396546- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Bone Metabolism and Diseases
- Enzyme Catalysis and Immobilization
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Circular RNAs in diseases
- 3D Printing in Biomedical Research
- Microbial Metabolic Engineering and Bioproduction
- Dental Implant Techniques and Outcomes
- Impact of Light on Environment and Health
- Building Energy and Comfort Optimization
- Mesenchymal stem cell research
- Plant biochemistry and biosynthesis
- Spine and Intervertebral Disc Pathology
- Nanoplatforms for cancer theranostics
- Heat Transfer and Boiling Studies
- Adsorption and Cooling Systems
- Heat Transfer and Optimization
- Ocean Acidification Effects and Responses
- Cannabis and Cannabinoid Research
- Venomous Animal Envenomation and Studies
- Pregnancy-related medical research
- Luminescence and Fluorescent Materials
- Animal testing and alternatives
Air Force Medical University
2022-2025
Xuzhou Medical College
2024
Nankai University
2024
South China University of Technology
2012-2022
Shanghai Ninth People's Hospital
2020-2022
Shanghai Jiao Tong University
2020-2022
State Key Laboratory of Luminescent Materials and Devices
2022
Sichuan University
2022
West China Hospital of Sichuan University
2022
National Clinical Research
2022
Manipulations of morphological properties nanobiomaterials have been demonstrated to modulate the outcome osteoimmunomodulation and eventually osteogenesis through innate immune response. However, functions mechanisms adaptive cells in process nanobiomaterials-mediated bone regeneration remained unknown. Herein, we developed bone-mimicking hydroxyapatite (HAp) nanorods with different aspect ratios as model materials investigate impacts nanoshape features on explore underlying focusing T...
The blood vessel system is essential for skin homeostasis and regeneration. While the heterogeneity of vascular endothelial cells has been emergingly revealed, whether a regeneration-relevant subtype exists in remains unknown. Herein, specialized vasculature featured by simultaneous CD31 EMCN expression contributing to regeneration process identified, decline which functionally underlies impaired angiogenesis diabetic nonhealing wounds. Moreover, enlightened developmental that mesenchymal...
Cyclical stretch-induced bone formation during orthodontic treatment is a complex biological process modulated by various factors including miRNAs and their targeted-gene network. However, the miRNA expression profile roles in osteogenic differentiation of mesenchymal stem cells (BMSCs) exposed to mechanical stretch remains unclear. Here, we use microarray assay screen for mechano-sensitive BMSCs identified that nine were differentially expressed between stretched control BMSCs. Furthermore,...
Synergistic promotion of osseointegration by nanostructure design and silicon substitution hydroxyapatite coatings in a diabetic model.
To deepen the understanding of structure-property relationship, three AIEgens named DBP, TBP, and TBP-SO3 are designed. By controlling ability D–A units, realizes efficient NIR emission a more rapid ROS generation ability.
The synergistic effect of chemical element doping and surface modification is considered a novel way to regulate cell biological responses improve the osteoinductive ability biomaterials.Hydroxyapatite (HAp) bioceramics with micro-nano-hybrid (a mixture microrods nanorods) surfaces different strontium (Sr) contents 2.5, 5, 10, 20% (Srx-mnHAp, x: 10 20%) were prepared via hydrothermal transformation method. Srx-mnHAp on osteogenesis angiogenesis bone marrow stromal cells (BMSCs) was evaluated...
The macrophage-dominated bone immune response plays an important role in osteogenesis of defects. Generally, M2 macrophages are beneficial to promote osteogenesis. However, recent studies have confirmed that M1 also early angiogenesis, osteointegration. Therefore, achieving sequential polarization from may be more for In this study, a new type immunomodulatory IFN-γ/Sr-dropped bioactive glass composite scaffold (IFN-γ/SrBG) was successfully prepared which integrates multiple biological...
Two coordination polymers, {[Cd(m-TTzPA)Br 2 ]·H O} n and {[Zn(m-TTzPA)Br , were synthesized based on (m-H TTzPA)(HSO 3 ) . All compounds show photochromic behaviors have obvious fluorescence quenching upon irradiation.
Abstract Harnessing natural developmental programs to repair and replace damaged organs represents promising approaches in regenerative medicine. However, effective strategies are still lacking for tissue regeneration complicated conditions, such as the periodontal bone defect. Here, human dental follicle stem cells (hDFSCs) their aggregates (hDFSCA) cultured characterized, which formed based on inherent property of these self‐assembly into compact spheroid‐like structures, mimicking...
Abstract Sympathetic cues via the adrenergic signaling critically regulate bone homeostasis and contribute to neurostress-induced loss, but mechanisms therapeutics remain incompletely elucidated. Here, we reveal an osteoclastogenesis-centered functionally important osteopenic pathogenesis under sympatho-adrenergic activation with characterized microRNA response efficient therapeutics. We discovered that osteoclastic miR-21 was tightly regulated by downstream β2-adrenergic receptor (β 2 AR)...
T1 lipase has received considerable attention due to its thermostability. Fatty acid specificity of (crude and purified) was investigated, potential in the synthesis acylglycerols also evaluated.Fatty investigated esterification fatty acids (C6:0 C18:3), suggesting that crude purified had lowest preference for C18:0 [specificity constant (1/α) = 0.08] followed by C18:1 (1/α 0.12) showed highest C8:0 1). A structural model constructed briefly explore interactions between substrate....
FTY720@MBGs improve bone regeneration by synergistically immunomodulating osteogenesis and osteoclastogenesis.
Concrete recycling is an important element of sustainable development. Demolished concrete lumps (DCLs) can be blended with fresh as a filler, but achieving good compactness the compound problem. An effective compactness-monitoring method for DCL needed urgently. In this study, simple and rugged lead zirconate titanate (PZT)-based smart aggregate (SA) monitoring using transient excitation was tested in laboratory. The same type sensor used both receiver transducer. level measured by directly...