A5005404442- Platelet Disorders and Treatments
- Byzantine Studies and History
- Classical Antiquity Studies
- Archaeology and Historical Studies
- Blood groups and transfusion
- Maritime and Coastal Archaeology
- Ancient Mediterranean Archaeology and History
- World Wars: History, Literature, and Impact
- Jewish and Middle Eastern Studies
- Ancient Near East History
- Eurasian Exchange Networks
- American Constitutional Law and Politics
- European Political History Analysis
- Historical Studies on Spain
- Military History and Strategy
- Historical Studies and Socio-cultural Analysis
- Colonialism, slavery, and trade
- Immunodeficiency and Autoimmune Disorders
- Islamic Studies and History
- Blood disorders and treatments
- Global Maritime and Colonial Histories
- Chronic Lymphocytic Leukemia Research
- Middle East Politics and Society
- Acute Lymphoblastic Leukemia research
- Historical and Religious Studies of Rome
Royal Manchester Children's Hospital
2016-2025
Boston Children's Hospital
2001-2025
University of Manchester
2013-2025
National Health Service
2024
Manchester Academic Health Science Centre
2011-2022
Institute of Cancer Research
2022
Institute of Immunology
2022
University of Cambridge
2021
Manchester University NHS Foundation Trust
2018-2020
Manchester University
2018-2019
Over the last decade, there have been numerous developments and changes in treatment practices for management of patients with immune thrombocytopenia (ITP). This article is an update International Consensus Report published 2010. A critical review was performed to identify all relevant articles between 2009 2018. An expert panel screened, reviewed, graded studies formulated updated consensus recommendations based on new data. The final document provides diagnosis ITP adults, during...
The objective of this document is to guide diagnosis and management patients with rare coagulation disorders (RCD). This replaces the 2004 UK Haemophilia Centre Doctors' Organization (UKHCDO) guideline (Bolton-Maggs et al, 2004a). RCD are here defined as monogenic bleeding caused by deficiency a soluble factor or factors, other than von Willebrand disease (VWD), A B. described in include heritable deficiencies fibrinogen, prothrombin, (F) V, FVII, FX, FXI FXIII, combined FV FVIII vitamin...
The objective of this guideline is to provide healthcare professionals with guidance on the management patients primary autoimmune haemolytic anaemia (AIHA). may not be appropriate every patient and in all cases individual circumstances dictate an alternative approach. Attempts categorise (AIHA) define its response treatment vary considerably published literature. Author defined criteria have been used guideline, but limits study comparisons will contributed differences reported outcome....
Objective Juvenile idiopathic arthritis (JIA) can persist through adolescence and adulthood, resulting in significant disability. The use of low-dose oral methotrexate (MTX) for persistent polyarthritis has been shown to be effective by the USA/USSR collaborative study group. However, 2 most disabling subgroups JIA, systemic extended oligoarthritis, were underrepresented that study. present was therefore conducted investigate efficacy MTX these subgroups. Methods Patients under age 16 years...
The objective of this guideline is to provide healthcare professionals with guidance on the management patients secondary autoimmune haemolytic anaemia (AIHA). may not be appropriate every patient and in all cases, individual circumstances dictate an alternative approach. Recommendations are based systematic review published English language literature from January 1960 October 2015 (see Appendix S1 for further details). Although recommendations unchanged, expanded version available as S2....
Abstract Comparative clinical studies of children and adults with immune thrombocytopenia (ITP) are poorly covered in the literature. However, accepted classification ITP—childhood ITP adult ITP—results considerable differences treatment protocols practice guidelines. The analysis Pediatric Adult Registry on Chronic (PARC‐ITP) patients at first presentation demonstrated fewer laboratory findings initial diagnosis between than expected. present report 2‐year follow‐up data supports hypothesis...
Abstract A record of prices basic commodities from Hellenistic Babylonia, even though incomplete, provides unusually detailed information about economic conditions there. From these prices, particularly for food, it is possible to derive conclusions concerning price levels and standards living over a period three centuries or so. The Seleucid revealed as one high prosperity, building on previous advance, but was followed by fall in during the first century Parthian rule.
Abstract Background Disease-specific quality of life (QoL) measures have enhanced the capacity outcome to evaluate subtle changes and differences between groups. However, when specific disease is rare, cohort patients small international collaboration often necessary accomplish meaningful research. As many QoL been developed in North American English, they require translation ensure their usefulness a multi-cultural and/or society. Published guidelines provide formal methods achieve...