A5051811954- Human Health and Disease
- Healthcare Systems and Public Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Cardiovascular Health and Risk Factors
- Digestive system and related health
- Vitamin D Research Studies
- Neuroscience of respiration and sleep
- Biomarkers in Disease Mechanisms
- Gut microbiota and health
- Advanced Glycation End Products research
- Sarcoidosis and Beryllium Toxicity Research
- Glycosylation and Glycoproteins Research
- Nutritional Studies and Diet
- Pregnancy and Medication Impact
- Microbial Metabolites in Food Biotechnology
- Medical Education and Admissions
- Smoking Behavior and Cessation
- Physical Education and Training Studies
- Medical and Biological Sciences
- Neutropenia and Cancer Infections
- Inhalation and Respiratory Drug Delivery
- Breastfeeding Practices and Influences
- Psychological Treatments and Assessments
- Microscopic Colitis
North-Western State Medical University named after I.I. Mechnikov
2025
Samara State Medical University
2015-2024
Ministry of Health of the Russian Federation
2016-2023
In-Q-Tel
2015
Suboptimal health status (SHS) is recognized as a subclinical, reversible stage of chronic disease. Association has been confirmed between SHS and cardiovascular risk factors, indicating that may contribute to the development This study explored integrated assessment disease by combining questionnaire-25 (SHSQ-25) indicators endothelial dysfunction.A community-based cross-sectional was conducted in sample 459 residents Samara, Russia, who had no history clinical diagnosed did not receive any...
Background/Objectives: Chronic obstructive pulmonary disease (COPD) is a significant public health concern, affecting millions of people worldwide. This study aims to use Surface-Enhanced Raman Scattering (SERS) technology detect the presence respiratory conditions, with focus on COPD. Methods: The samples human serum from 41 patients diseases (11 COPD, 20 bronchial asthma (BA), and 10 asthma–COPD overlap syndrome) 103 ischemic heart disease, complicated by chronic failure (CHF), were...
It is known that iron deficiency a negative factor for the onset of pregnancy. aggravates its course, increasing risk preeclampsia, placental insufficiency, uterine inertia, premature birth, bleeding and hypogalactia. This condition increases unfavorable outcomes, anemia cognitive delay in child. Raising awareness women reproductive age clinical suspicion physicians regarding latent can facilitate timely visit doctor. At expert council "Relevant issues Russian Federation" held June 2020,...
The article presents the data of a retrospective analysis average per capita consumption food by population Samara region in comparison with all-Russian indicators and recommended values period from 2010 to 2015, as well actual nutrition different groups working-age 2015 (2154 people aged 18 up 62 years age, 1179 them women, 975 men) using method 24-hour reproduction frequency quantitative assessment consumed products, dynamics prevalence alimentary-dependent diseases. Estimation parameters...
Summary. A multicenter (12 centers) retrospective analysis of health status 83 sarcoidosis patients in time diagnosis and after 10 years treatment has been performed. In diagnosis, 47 % the had complete remission pulmonary manifestations; mean forced spirometric values have not reduced (excluding initially treated with anti-TB drugs). Patients systemic steroids or during yrs were less likely to (36.5 %) more recurrent course (57.1 compared those steroids. Pentoxifylline administration...
Late diagnosis of chronic obstructive pulmonary disease (COPD) at advanced stage, high risk exacerbations, low compliance patients, and adverse effects treatment have been still unresolved problems in the COPD despite development new drugs. The personalized medicine rneeds distinct indications predictors efficacy safety treatment. Budesonide/formoterol fixed combination is recommended for patients with asthma – overlap syndrome bronchitis phenotype, blood eosinophilia > 300 cells/mm 3 ,...
Vlasenko NJu.Issledovanie urovnja kortizola i ego cirkadiannogo ritma u pozharnyh [The study of cortisol level and its circadian rhythm in the fire].Simvol nauki Symbol science].2016; 1-3: 17-18.8. Chernyshova TE, Reverchuk IV, Melikyan AI.Stress kak prediktor metabolicheskogo sindroma [Stress as a predictor metabolic syndrome].Lichnost' v jekstremal'nyh uslovijah krizisnyh situacijah zhiznedejatel'nosti [Personality extreme conditions crisis situations life].2013; 3: 106-109.9. Xiaoyan Chu,...
The aim of this study was to determine a relationship between IL-17, IL-10 and vitamin D concentrations asthma control level in adult patients. Methods . This comparative which involved 79 patients were divided two groups: 48 with good (mean age, 52 ± 13 years; BMI, 24.9 (21.6 – 28.3) kg/m2) 31 uncontrolled 57.6 7.9 29.1 (27.3 33.6) kg/m2). Concentrations IL-10, IL-17 measured blood serum using ELISA assay. Results. Vitamin concentration significantly lower compared well-controlled asthma....
The patient, who has risk factors but considers himself / herself to be healthy, does not consult a doctor, is in suboptimal status. study of the patient’s health at different levels physical activity an important issue preventive medicine. Material and methods . 351 people (133 men 218 women) aged 18 75 years after obtaining voluntary informed consent were examined. Patients divided into 8 groups according international questionnaire (IPAQ). In addition classic clinical laboratory...
In healthcare, a new digital branch of medicine has emerged – telemedicine, which is especially relevant for primary healthcare. To ensure the quality functioning telemedicine centers, it important to provide timely and high-quality training medical personnel in field knowledge. The solution this problem entrusted leading universities country. article devoted generalization experience teaching technologies at Department Family Medicine with course Samara State Medical University levels...
BACKGROUND: Arterial hypertension is a common cardiovascular disease that requires constant monitoring by doctor of drug therapy to achieve the target blood pressure level.
 AIM: To analyze pharmacotherapy essential in patients, who have achieved controlled course disease.
 MATERIALS AND METHODS: In this study 274 patients with stage 2 arterial and no comorbidities were recruited. Blood indicators, anthropometric data, results laboratory instrumental studies, volume for...
Relevance. Metabolic disorders in non-alcoholic fatty liver disease play a significant role the development and progression of cardiovascular diseases, accelerating their occurrence, aggravating course outcomes. The occurrence maintenance chronic staged (from hepatosis steatohepatitis to progressive fibrosis) is associated with quantitative qualitative changes composition intestinal microflora. At same time, outpatients may consider themselves healthy, which makes it difficult implement...
The functional responsibilities of general practitioners (family doctors) (GPs) have changed significantly over the past decade. number GP functions has expanded. Despite increasingly complex professional activities GPs, there is no scientific evidence for qualification characteristics GPs expressed in knowledge, skills, abilities, and competencies theory practice training. In this regard, a study was conducted to determine priority that make up specialist. Aim. To analyze, generalize...
Patients who have cardiovascular risk factors (CVD) consider themselves healthy. They no active complaints, and they will not go to the doctor. In this regard, in outpatients be considering healthy sill sufficiently studied. For early detection of factors, SCORE scale is used. The researchers also offered IPAQ SHSQ-25 questionnaires. Aim . To study severity depending on their physical activity presence suboptimal health status. Material methods 358 people (155 men 203 women aged 18 60 years)...
Currently, a new branch of medicine – glycomedicine is starting to show the important role carbohydrates and their interaction with macromolecules in pathogenesis many diseases. Their roles respiratory system diseases development are not an exception. In this review we tried determine current views on glycans, glycation products receptors diseases; opportunities using these biological molecules for diagnostics, verification risk severity; feasible usage as therapeutic targets disease...
Bronchial asthma is a widespread disease that becoming increasingly costly to the medical and financial systems of many countries with each passing year. The rising prevalence bronchial necessitates search for most efficient diagnostic treatment strategies various phenotypes, including some are relatively uncommon.
 From this point view, glycomics appears be one interesting perspective branches medicine. This research area studies carbohydrate complexes their roles in development...
ЯКУНОВА ЕЛЕНА МИХАйЛОВНА
The earliest correction of behavioral risk factors for chronic non-communicable diseases will reduce the rates premature mortality population. Currently, relationship between altered spectrum intestinal microflora in various indicators suboptimal health status and body mass index is not sufficiently studied. When they are a state status, patients consider themselves healthy do go to doctor long time, which makes it difficult implement early preventive measures this group patients. Goal. To...
Sedentary lifestyle, being a behavioral risk factor for chronic non-communicable diseases, is relevant preventive medicine. A key role in the correction of factors diseases occupied by general medical practice, where patient continuously observed many years. Increased physical activity reduces atherosclerosis, musculoskeletal system, malignant tumors, has positive effect on psychological state patients and overall morbidity mortality. Increasing reserves cardiorespiratory system body,...
According to the WHO, 30.9% of adult population Russian Federation are active smokers. From 30% 43% smoking patients with COPD not able give up nicotine despite diagnosis and deterioration health. Most publications related treatment do distinguish into a separate group. The purpose this study is comparative analysis effectiveness LAMA (Tiotropium bromide Glycopyrronium bromide) LABA \ (Olodaterol + tiotropium Indacaterol bromide). involved 102 high degree addiction irreversible bronchial...
Objectives to analyze the quality and quantity of intestinal microflora relatively healthy people and/or those who did not visit a doctor in last 3 months, before 1 month after taking meta-prebiotic complex containing dietary fiber (inulin) oligosaccharides (oligofructose).
 Material methods. We examined individuals considered themselves consult during past months. To detect presence dyspeptic complaints, clinical data were collected. 114 with different suboptimal status non-specific...
<b>Background:</b> Vitamin D has effects both on the innate and adaptive immune system. Low vitamin level is associated with poor asthma control. <b>Aim:</b> To assess ratio between serum risk of developing adult-onset metabolic syndrome. <b>Methods:</b> A total 46 adults were enrolled (Age=58,55±8,33, BMI=31,2±5,9). We measured 25-OH level, triglycerides, LDL-C, HDL-C, glucose, insulin, leptin. <b>Results:</b> significantly depended severity asthma.(intermittent BA- 20,15±4,07 ng/ml, mild...