A5026034674- Renal Transplantation Outcomes and Treatments
- Hepatitis C virus research
- Urological Disorders and Treatments
- COVID-19 Clinical Research Studies
- COVID-19 Impact on Reproduction
- Long-Term Effects of COVID-19
- Acute Kidney Injury Research
- Immunotherapy and Immune Responses
- Urinary and Genital Oncology Studies
- Vaccine Coverage and Hesitancy
- Innovations in Medical Education
- Neurological and metabolic disorders
- Dialysis and Renal Disease Management
- Liver Disease and Transplantation
- SARS-CoV-2 and COVID-19 Research
- Bladder and Urothelial Cancer Treatments
- Stoma care and complications
- Neurological Complications and Syndromes
- Cancer survivorship and care
- Organ Donation and Transplantation
- Education, Sociology, Communication Studies
- Anorectal Disease Treatments and Outcomes
- Muscle and Compartmental Disorders
- Fungal Infections and Studies
- Pressure Ulcer Prevention and Management
University of Pennsylvania
2018-2022
Penn Center for AIDS Research
2021-2022
University of Pennsylvania Health System
2021-2022
Akron General Medical Center
2017
Cleveland Clinic
2017
Baystate Medical Center
2014-2016
Pennsylvania Hospital
2016
Hospital of the University of Pennsylvania
2016
Tufts University
2014
Beaumont Hospital
2011-2013
Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has led to significant reductions in transplantation, motivated part by concerns of disproportionately more severe among solid organ transplant (SOT) recipients. However, clinical features, outcomes, and predictors mortality SOT recipients are not well described. Methods We performed a multicenter cohort study with laboratory-confirmed COVID-19. Data were collected using standardized intake 28-day follow-up electronic case...
Most studies of solid organ transplant (SOT) recipients with COVID-19 focus on outcomes within one month illness onset. Delayed mortality in SOT hospitalized for has not been fully examined.
Kidney transplantation (KT) from deceased donors with hepatitis C virus (HCV) into HCV-negative recipients has become more common. However, the risk of complications such as BK polyomavirus (BKPyV) remains unknown. We assembled a retrospective cohort at four centers. matched HCV-viremic kidneys to highly similar HCV-aviremic on established factors for BKPyV. To limit bias, matches were within same center. The primary outcome was BKPyV viremia ≥1000 copies/ml or biopsy-proven nephropathy;...
SUMMARY Vaccine-mediated immunity often relies on the generation of protective antibodies and memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth comparison GC responses elicited by SARS-CoV-2 mRNA vaccines in healthy immunocompromised individuals has not yet been performed due to challenge directly probing human lymph nodes. In this study, through a fine-needle-aspiration-based approach, we profiled immune nodes kidney transplant (KTX) recipients. We found...
Donor acute kidney injury (AKI) activates innate immunity, enhances HLA expression in the allograft, and provokes recipient alloimmune responses. We hypothesized that inflammation manifested deceased-donor urine biomarkers would be associated with higher rates of biopsy-proven rejection (BPAR) allograft failure after transplantation.
We report a case of primary transitional cell carcinoma (TCC) bladder diverticum along with literature review. A 55-year-old male presented painless gross hematuria. histological diagnosis TCC within diverticulum was made following cystoscopical examination. Initially transurethral resection tumour subsequent intravesical chemotherapy followed. As result recurrence and in view bladder-sparing therapy, distal partial cystectomy performed. This demonstrates that conservative treatment can be...
Kidney transplant (KT) recipients experience high rates of early (≤30 days) hospital readmission (EHR) after KT, and existing studies provide limited data on modifiable discharge factors that may mitigate EHR risk.We performed a retrospective cohort study 468 adult deceased donor KT transplanted between 4/2010 11/2013 at 5 United States centers. We fit multivariable mixed effects models to assess the association two potentially with probability KT: (i) weekend (ii) days first scheduled...
Background. Historically, many organs from deceased donors with hepatitis C virus (HCV) were discarded. The advent of highly curative direct-acting antiviral (DAA) therapies motivated transplant centers to conduct trials transplanting HCV-viremic (nucleic acid amplification test positive) into HCV-negative recipients, followed by DAA treatment. However, the factors that influence candidates’ decisions regarding acceptance are not well understood. Methods. To explore patient-level...
Background Engaging in scholarly activity during residency can facilitate the acquisition of important skills; however, residents may encounter barriers such as unclear expectations to what constitutes scholarship, a paucity dedicated time and lack mentorship. Residents scholarship Objective In July 2013, we developed Case Report Curriculum (CRC) for first-year guide them towards creating high-quality case report helping achieve Accreditation Council Graduate Medical Education requirement....
Introduction: Transurethral resection of the prostate is one most common surgical procedures performed in men to relieve bladder outlet obstruction, often due benign prostatic hyperplasia. However, transurethral may also be used patients with metastatic cancer who have obstruction. Acute kidney injury after has been described and attributed a variety mechanisms, including acute tubular necrosis, rhabdomyolysis, hemolysis heme-pigment nephropathy. our knowledge, no case biopsy-proven...
A radiographic incidental finding (sometimes called an incidentaloma) is defined as a structure that unintentionally found during exam for unrelated indication. The increased use of routine abdominal imaging associated with rising incidence in incidentalomas the kidney 1. In one meta-analysis, 75% renal were benign 2. However, overall prevalence carcinomas low at 0.2% 3. With growing uptake POCUS, healthy volunteers clinical demonstrations may find themselves new findings despite lack...
127 Background: Hospice care can improve quality of life (QOL) for patients with advanced cancer. Studies suggest that hospice services are offered late in the course terminal illness; limiting patient comfort and QOL. Limited literature exists on barriers to timely referral. We examined demographic clinical characteristics associated hypothesized age, malignancy type, performance status (PS) may predict referral hospice. Methods: Patients were age 18+ cared by oncologists Baystate Medical...
We report a case of primary transitional cell carcinoma (TCC) ofa bladder diverticum along with literature review. A 55-year-oldmale presented painless gross hematuria. histological diagnosisof TCC within diverticulum was made followingcystoscopical examination. Initially transurethral resection bladdertumour subsequent intravesical chemotherapy followed.As result recurrence and in view bladder-sparing therapy, adistal partial cystectomy performed. This demonstratesthat conservative...