Ryan C. Ashbaugh

ORCID: 0000-0003-2671-1954
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About
Contact & Profiles
Research Areas
  • Electromagnetic Fields and Biological Effects
  • Photoreceptor and optogenetics research
  • Molecular Communication and Nanonetworks
  • Transcranial Magnetic Stimulation Studies
  • Fish biology, ecology, and behavior
  • Microfluidic and Bio-sensing Technologies
  • Marine animal studies overview
  • Pain Management and Treatment
  • Neuroscience and Neural Engineering
  • Muscle activation and electromyography studies
  • Pain Mechanisms and Treatments
  • Bacteriophages and microbial interactions

Michigan State University
2019-2024

Michigan United
2021

The ability to manipulate cellular function using an external stimulus is a powerful strategy for studying complex biological phenomena. One approach modulate the of environment split proteins. In this method, biologically active protein or enzyme fragmented so that it reassembles only upon specific stimulus. Although many tools are available induce these systems, nature has provided other mechanisms expand toolbox. Here, we show novel method reconstituting proteins magnetic stimulation. We...

10.3389/fbioe.2024.1355915 article EN cc-by Frontiers in Bioengineering and Biotechnology 2024-03-28

BackgroundTwenty million Americans suffer from peripheral nerve injury. These patients often develop chronic pain and sensory dysfunctions. In the past decade, neuroimaging studies showed that these changes are associated with altered cortical excitation-inhibition balance maladaptive plasticity. We tested if neuromodulation of deprived cortex could restore balance, whether it would be effective in alleviating complications.ObjectiveWe non-invasive repetitive transcranial magnetic...

10.1016/j.brs.2020.10.006 article EN cc-by-nc-nd Brain stimulation 2020-10-15

Several marine species have developed a magnetic perception that is essential for navigation and detection of prey predators. One these the transparent glass catfish contains an ampullary organ dedicated to sense fields. Here we examine behavior in response static fields which will provide valuable insight on function this response. By utilizing state art animal tracking software artificial intelligence approaches, quantified effects swimming direction catfish. The results demonstrate placed...

10.1371/journal.pone.0248141 article EN cc-by PLoS ONE 2021-03-05

Magnetogenetics is a new field that utilizes electromagnetic fields to remotely control cellular activity. In addition the development of biological genetic tools, this approach requires designing hardware with specific set demands for electromagnets used provide desired stimulation electrophysiology and imaging experiments. Here, we present universal stimulus delivery system comprising four magnet designs compatible electrophysiology, fluorescence luminescence imaging, microscopy, freely...

10.3390/bios11080248 article EN cc-by Biosensors 2021-07-25

Abstract The ability to manipulate cellular function using an external stimulus is a powerful strategy for studying complex biological phenomena. One approach modulate the of environment split proteins. In this method, biologically active protein or enzyme fragmented so that it reassembles only upon specific stimulus. While there are many tools available induce these systems, nature has provided other mechanisms can be utilized expand toolbox. Here we show novel method reconstituting...

10.1101/2022.11.30.518522 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-11-30

ABSTRACT Magnetogenetics is a new field that utilizes electromagnetic fields to remotely control cellular activity. In addition the development of biological genetic tools, this approach requires designing hardware with specific set demands for electromagnets used provide desired stimulation electrophysiology and imaging experiments. Here we present universal stimulus delivery system comprised four magnet designs compatible electrophysiology, fluorescence luminescence imaging, microscopy,...

10.1101/2021.06.07.447412 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-06-07

Abstract Peripheral nerve injury leads to altered cortical excitation-inhibition balance which is associated with sensory dysfunctions. We tested if non-invasive repetitive transcranial magnetic stimulation (rTMS) has shown induce neuronal excitability, and cell-specific activation via the Electromagnetic-perceptive gene (EPG) a novel that was identified cloned from Kryptopterrus bicirrhis demonstrated evoke neural responses when magnetically stimulated, can restore excitability. A battery...

10.1101/851444 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-11-22

Abstract Several marine species have developed a magnetic perception that is essential for navigation and detection of prey predators. One these the transparent glass catfish contains an ampullary organ dedicated to sense fields. Here we examine behavior in response static fields which will provide valuable insight on function this response. By utilizing state art animal tracking software artificial intelligence approaches, quantified effects swimming direction catfish. The results...

10.1101/2020.08.13.250035 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-08-14
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