- Physiological and biochemical adaptations
- Lanthanide and Transition Metal Complexes
- Fish biology, ecology, and behavior
- Aquaculture Nutrition and Growth
- Photoreceptor and optogenetics research
- Microfluidic and Bio-sensing Technologies
- Molecular Communication and Nanonetworks
- Electromagnetic Fields and Biological Effects
- Geochemistry and Elemental Analysis
- Radioactive element chemistry and processing
- Neuroscience and Neural Engineering
- Genetics, Bioinformatics, and Biomedical Research
- Nanoparticle-Based Drug Delivery
- Cancer Research and Treatments
- bioluminescence and chemiluminescence research
- Advanced biosensing and bioanalysis techniques
- Ichthyology and Marine Biology
- Bacteriophages and microbial interactions
- Evolution and Genetic Dynamics
- Fractal and DNA sequence analysis
- Insect and Arachnid Ecology and Behavior
- Evolutionary Game Theory and Cooperation
- Marine animal studies overview
Michigan State University
2020-2025
Quantitative BioSciences
2020
Abstract Several hundreds of tons gadolinium‐based contrast agents (GBCAs) are being dumped into the environment every year. Although macrocyclic GBCAs exhibit superior stability compared to their linear counterparts, we have found that structural integrity chelates is susceptible ultraviolet light, regardless configuration. In this study, present a synthetic protein termed GLamouR binds and reports gadolinium in an intensiometric manner. We then explore extraction from MRI patient urine as...
Genetically encoded optical sensors and advancements in microscopy instrumentation techniques have revolutionized the scientific toolbox available for probing complex biological processes such as release of specific neurotransmitters. Most genetically currently used are based on fluorescence been highly successful tools single-cell imaging superficial brain regions. However, there remains a need to develop new reporting neuronal activity vivo within deeper structures without hardware lenses...
The ability to manipulate cellular function using an external stimulus is a powerful strategy for studying complex biological phenomena. One approach modulate the of environment split proteins. In this method, biologically active protein or enzyme fragmented so that it reassembles only upon specific stimulus. Although many tools are available induce these systems, nature has provided other mechanisms expand toolbox. Here, we show novel method reconstituting proteins magnetic stimulation. We...
Studies at the cellular and molecular level of magnetoreception-sensing responding to magnetic fields-are a relatively new research area. It appears that different mechanisms magnetoreception in animals evolved from origins, and, therefore, many questions about its remain left open. Here we present information regarding Electromagnetic Perceptive Gene (EPG)
Abstract Several hundreds of tons gadolinium-based contrast agents (GBCAs) are being dumped into the environment every year. Although macrocyclic GBCAs exhibit superior stability compared to their linear counterparts, we have found that structural integrity chelates susceptible ultraviolet light, regardless configuration. In this study, present a synthetic protein termed GLamouR binds and reports gadolinium in an intensiometric manner. We then explore extraction from GBCA-spiked artificial...
Abstract The ability to manipulate cellular function using an external stimulus is a powerful strategy for studying complex biological phenomena. One approach modulate the of environment split proteins. In this method, biologically active protein or enzyme fragmented so that it reassembles only upon specific stimulus. While there are many tools available induce these systems, nature has provided other mechanisms can be utilized expand toolbox. Here we show novel method reconstituting...
Summary Studies at the cellular and molecular level of magnetoreception – sensing responding to magnetic fields is a relatively new research area. As it appears that different mechanisms in animals evolved from origins, many questions about remain left open. Here we present information regarding Electromagnetic Perceptive Gene (EPG) Kryptopterus vitreolus may serve as part foundation understanding applying magnetoreception. Using HaloTag coupled with fluorescent ligands phosphatidylinositol...
Sustainable products are becoming an integral part of our daily lives - in this study, we biosynthetically produced MRI contrast agent from E.coli with r1 6.0 (per-gadolinium, 7T field strength, room temperature) that provides the user optical feedback through a jump green fluorescence upon binding free gadolinium solution. We anticipate will reduce amount resources spent on quality control (in assessing unchelated could otherwise introduce toxicity), whereas its compatibility lyophilization...
For thousands of years, a war has been waged between hackers and cryptographers1. Cryptographers find safe way to store transport information, attempt access it. Today, this is on much more microscopic scale, as new storage methods, like ones utilizing DNA are developed, cryptographers need protect the data from malicious entities1,2. A solution may lie in proteins human cell attaching information onto these while preserving their function. Even though there encryption schemes that managed...