A5101453425- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Metal complexes synthesis and properties
- Magnetism in coordination complexes
- Advanced Drug Delivery Systems
- Nonlinear Optical Materials Studies
- Drug Solubulity and Delivery Systems
- Organometallic Compounds Synthesis and Characterization
- biodegradable polymer synthesis and properties
- Analytical Methods in Pharmaceuticals
- Nonlinear Optical Materials Research
- Crystallography and molecular interactions
- Mitochondrial Function and Pathology
- Spectroscopy and Chemometric Analyses
- Rheumatoid Arthritis Research and Therapies
- Metabolomics and Mass Spectrometry Studies
- Curcumin's Biomedical Applications
- Luminescence and Fluorescent Materials
- Dendrimers and Hyperbranched Polymers
- Bone Metabolism and Diseases
- Crystal structures of chemical compounds
- Molecular Sensors and Ion Detection
- Polyoxometalates: Synthesis and Applications
- Polymer Synthesis and Characterization
Guilin Medical University
2014-2021
State Council of the People's Republic of China
2019
Qingdao University of Science and Technology
2009-2012
The purpose of this study was to demonstrate that inhibiting crystallization by HPMCAS played a key role in enhancing dissolution and absorption piperine (Pip) from its amorphous solid dispersion (ASD). Nucleation induction time supersaturation tests were used evaluate the ability polymers inhibit Pip. prepared dispersions characterized DSC FTIR. rate Pip ASDs assayed test. permeability investigated single-pass intestinal perfusion studies. order HF > MF LF L100-55. best inhibition effect...
Abstract Rheumatoid arthritis is a chronic autoimmune disease characterized by the infiltration of synovial inflammatory cells and progressive joint destruction. Total flavonoids Bidens pilosa have been used against inflammation in rheumatoid arthritis, but its role bone destruction remains to be explored. The aim this paper was study whether total B. relieve severity collagen-induced rats, particularly it regulates production proinflammatory cytokines receptor activator nuclear...
The purpose of this study was to enhance quercetin (Que) dissolution by preparing its ternary amorphous solid dispersions. dispersions were prepared solvent evaporation method using hydroxypropylmethylcellulose acetate succinate (HPMCAS) and L-lysine (lys) as the carriers. effect combination polymer amino acid on nucleation inhibition evaluated induction time. Supersaturation tests used investigate ability maintaining Que supersaturation lys. results showed that better than binary Stronger...
Abstract A new candidate [Cu(PPh 3 ) 2 Him]Br ( 1 , PPh =triphenylphosphine, Him=1‐ H ‐imidazole) for nonlinear optical (NLO) materials has been synthesized and characterized crystallographically. The third‐order NLO properties were measured by the Z ‐scan technique with an 8 ns pulsed laser at 532 nm. Compound exhibits strong absorptive abilities [ α =(61±5)×10 −12 ] effective self‐focusing performance n =(15±3)×10 −18 m ·W −1 in 1.01×10 −4 mol·dm −3 DMF solution. compound also luminescence...
Two new complexes Zn(TBimE)Cl2 1 and Cd(TBimE)(I)2 2 based on a semi-rigid ligand TBimE (TBimE = (E)-1,2-bis(2-benzimidazolyl)ethane) have been synthesized their structures determined by X-ray single crystal diffractometry. diffraction analyses reveal that the “trans” is converted into “cis” conformation in of complexes, so can be used as bidentate to chelate Zinc(II) Cadmium(II) ions. Both exhibit distorted tetrahedral geometries central metal atoms are coordinated two N from anions. The...
To enhance in vitro dissolution of Cur by preparing solid dispersions. The ability HPMCAS-HF,HPMCAS-MF,HPMCAS-LF and PVPK30 to maintain supersaturated solution was investigated supersaturation test. Amorphous dispersions were prepared the solvent-evaporation method. samples characterized using infrared spectroscopy( IR) differential scanning calorimetry( DSC),and investigated. DSC IR results showed that 1 ∶3 ∶9 dispersions,Cur amorphously dispersed carrier,and interaction existed between...