A5100749093- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Pancreatic and Hepatic Oncology Research
- Ferroptosis and cancer prognosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Gallbladder and Bile Duct Disorders
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Pediatric Hepatobiliary Diseases and Treatments
- Neurological Disease Mechanisms and Treatments
- Medical Imaging and Pathology Studies
- Intracranial Aneurysms: Treatment and Complications
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Acupuncture Treatment Research Studies
- Aortic Disease and Treatment Approaches
- Pancreatitis Pathology and Treatment
- Spinal Fractures and Fixation Techniques
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Epilepsy research and treatment
- Esophageal Cancer Research and Treatment
- MicroRNA in disease regulation
Shaoxing University
2025
The First People's Hospital of Changde
2023-2025
Hangzhou First People's Hospital
2025
Second Affiliated Hospital of Zhejiang University
2025
Central South University
2020-2025
Hunan Cancer Hospital
2020-2025
University of Louisville
2024
First Hospital of Jilin University
2024
Jilin University
2024
Army Medical University
2014-2024
The liver and the mononuclear phagocyte system are a frequent target for engineered nanomaterials, either as result of particle uptake spread from primary exposure sites or systemic administration therapeutic imaging nanoparticles. In this study, we performed comparative analysis toxicological impact 29 metal oxide nanoparticles (NPs), some commonly used in consumer products, transformed Kupffer cells (KCs) hepatocytes. We not only observed differences between KCs hepatocytes, but also...
Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with lowest survival rate, primarily arising from chronic inflammation. To better characterize progression inflammation to cancer metastasis, we performed single-cell RNA sequencing across samples of 6 cholecystitis, 12 treatment-naive GBCs, and matched metastases. Benign epithelial cells inflamed gallbladders displayed resting, immune-regulating, gastrointestinal metaplastic phenotypes. A small amount PLA2G2A+ copy...
Tissue sampling of biliary tract carcinomas (BTCs) for molecular characterization is challenging. The aim this study was to investigate the possibility identifying individual actionable mutations derived from bile cell‑free DNA (cfDNA) using targeted deep sequencing. Ten BTC patients, four with gallbladder and six cholangiocarcinomas, were enrolled in present study. Using sequencing a panel 150 tumor‑related genes, paired cfDNA tumor analyzed mutational variants individually then compared....
High-salt diet-induced cardiac hypertrophy and fibrosis are associated with increased reactive oxygen species production. Transient receptor potential vanilloid type 1 (TRPV1), a specific for capsaicin, exerts protective role in remodeling that resulted from myocardial infarction, peroxisome proliferation-activated receptors δ (PPAR- ) play an important metabolic myocardium remodeling. However, it remains unknown whether activation of TRPV1 could alleviate the effect cross-talk between PPAR-...
Early detection of platinum resistance for ovarian cancer treatment remains challenging. This study aims to develop a machine learning model incorporating genomic data such as Single-Nucleotide Polymorphisms (SNPs) Human Sulfatase 1 (SULF1) with CT radiomic based on pre-treatment images, predict (OC) treatment.A cohort 102 patients pathologically confirmed OC was retrospectively enrolled into this from January 2006 February 2018. All had platinum-based chemotherapy after maximal...
Accelerated urbanization and improved living standards have brought attention to kitchen space utilization sustainability. This paper explores innovative designs achieve Resilient storage, improve resource saving. The feasibility of the design solution is evaluated through comparative analysis user research. storage strategies based on sustainable development are proposed provide reference for future design.