David G. Goldfarb

ORCID: 0000-0003-2682-7543
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About
Contact & Profiles
Research Areas
  • Occupational Health and Performance
  • Injury Epidemiology and Prevention
  • Occupational and environmental lung diseases
  • Traffic and Road Safety
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Trauma and Emergency Care Studies
  • Noise Effects and Management
  • Pregnancy-related medical research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Radiation Dose and Imaging
  • Disaster Response and Management
  • Advanced Statistical Process Monitoring
  • Sarcoidosis and Beryllium Toxicity Research
  • Occupational exposure and asthma
  • Childhood Cancer Survivors' Quality of Life
  • Air Quality and Health Impacts
  • Acute Myeloid Leukemia Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Anatomy and Medical Technology
  • Surgical Simulation and Training
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Cancer Risks and Factors
  • Ultrasound in Clinical Applications
  • Scientific Measurement and Uncertainty Evaluation
  • Health and Medical Research Impacts

Montefiore Medical Center
2016-2025

New York City Fire Department
2017-2025

Albert Einstein College of Medicine
2020-2025

City University of New York
2021-2024

Icahn School of Medicine at Mount Sinai
2021-2023

Steinhauser (Czechia)
2019

The Bronx Defenders
2019

SUNY Downstate Health Sciences University
2017-2018

Baylor College of Medicine
2013

Palmerston North Hospital
2009-2010

The World Trade Center (WTC) attacks on September 11, 2001, created an unprecedented environmental exposure to known and suspected carcinogens suggested increase the risk of multiple myeloma. Multiple myeloma is consistently preceded by precursor states monoclonal gammopathy undetermined significance (MGUS) light-chain MGUS, detectable in peripheral blood.To characterize WTC-exposed firefighters with a diagnosis conduct screening study for MGUS MGUS.Case series diagnosed between July 1,...

10.1001/jamaoncol.2018.0509 article EN cc-by JAMA Oncology 2018-04-26

Statistically significantly increased cancer incidence has been reported from 3 cohorts of World Trade Center (WTC) disaster rescue and recovery workers. We pooled data across these to address ongoing public concerns regarding risk 14 years after WTC exposure.From a combined deduplicated cohort 69 102 workers, sample 57 402 workers enrolled before 2009 followed through 2015 was studied. Invasive cancers diagnosed in 2002-2015 were identified 13 state registries. Standardized ratios (SIRs)...

10.1093/jnci/djab165 article EN cc-by-nc-nd JNCI Journal of the National Cancer Institute 2021-09-08

INTRODUCTION: The Revised Electronic Causality Assessment Method (RECAM) is an updated, electronic version of the Roussel Uclaf (RUCAM) to diagnose drug-induced liver injury (DILI). primary aim this study was compare RECAM vs RUCAM in patients with suspected DILI. METHODS: Patient encounters from October 1, 2015, September 30, 2019, were searched for DILI using ICD-10 K71 codes toxic disease. Network (DILIN) expert opinion scores assigned each case (1/2/3 = probable DILI, 4/5 non-DILI). and...

10.14309/ajg.0000000000003147 article EN The American Journal of Gastroenterology 2024-10-18

<h3>Importance</h3> Elevated incidence rates of thyroid cancer among World Trade Center (WTC)–exposed individuals may be associated with the identification asymptomatic cancers during medical surveillance. <h3>Objective</h3> To examine association between WTC exposure and Fire Department City New York (hereafter, Department) rescue/recovery workers as well <h3>Design, Setting, Participants</h3> This closed-cohort study classified method detection (asymptomatic symptomatic) in 14 987 men...

10.1001/jamainternmed.2020.0950 article EN JAMA Internal Medicine 2020-04-20

Objective To compare mortality rates in World Trade Center (WTC)-exposed Fire Department of the City New York (FDNY) firefighters with similarly healthy, non-WTC-exposed/non-FDNY firefighters, and each firefighter cohort general population. Methods 10 786 male WTC-exposed FDNY 8813 non-WTC-exposed from other urban fire departments who were employed on 11 September 2001 included analyses. Only received health monitoring via WTC Health Programme (WTCHP). Follow-up began ended at earlier death...

10.1136/oemed-2022-108703 article EN Occupational and Environmental Medicine 2023-03-27

Sarcoidosis is a systemic granulomatous disease of unknown etiology. It may develop in response to an exposure or inflammatory trigger the background genetically primed abnormal immune response. Thus, genetic studies are potentially important our understanding pathogenesis sarcoidosis. We developed case-control study which explored variations between firefighters Fire Department City New York (FDNY) with World Trade Center (WTC)-related sarcoidosis and those WTC exposure, but without The...

10.3390/ijerph16101830 article EN International Journal of Environmental Research and Public Health 2019-05-23

Objective: In occupational hearing conservation programmes, age adjustments may be used to subtract expected effects. Adjustments in the U.S. came from a small dataset and overlooked important demographic factors, ages, stimulus frequencies. The present study derived set of population-based adjustment tables validated them using database exposed workers.Design: Cross-sectional retrospective longitudinal cohort for validation.Study sample: Data National Health Nutrition Examination Survey...

10.1080/14992027.2019.1698068 article EN cc-by-nc-nd International Journal of Audiology 2019-12-17

Three cohorts including the Fire Department of City New York (FDNY), World Trade Center Health Registry (WTCHR), and General Responder Cohort (GRC), each funded by Program have reported associations between WTC-exposures cancer. Results generally been consistent with effect estimates for excess incidence all cancers ranging from 6 to 14% above background rates. Pooling would increase sample size de-duplicate cases cohorts. However, pooling required time consuming steps: obtaining...

10.3390/ijerph18041386 article EN International Journal of Environmental Research and Public Health 2021-02-03

Abstract Background World Trade Center (WTC)‐exposed responders may be eligible to receive no‐cost medical monitoring and treatment for certified conditions, including cancer. The survival of with cancer has not previously been investigated. Methods This study compared the estimated relative WTC‐exposed who developed while enrolled in two WTC programs New York City (WTC‐MMTP responders) (WTC‐non‐MMTP non‐responders from State (NYS‐non‐responders), all restricted 11‐southernmost NYS counties,...

10.1002/ajim.23278 article EN American Journal of Industrial Medicine 2021-07-19

World Trade Center (WTC) exposure is associated with obstructive airway diseases and sarcoidosis. There limited research regarding the incidence progression of non-sarcoidosis interstitial lung (ILD) after WTC-exposure. ILD encompasses parenchymal which may lead to progressive pulmonary fibrosis (PPF). We used Fire Department City New York's (FDNY's) WTC Health Program cohort estimate progression.

10.1007/s00408-024-00697-z article EN cc-by Lung 2024-05-07

In the use of medical device procedures, learning effects have been shown to be a critical component safety surveillance. To support their estimation these effects, we evaluated multiple methods for modeling rates within complex simulated dataset representing patients treated by physicians clustered institutions. We employed unique curves incorporate hierarchy between institution and then modeled them established that work with hierarchical data such as generalized estimating equations (GEE)...

10.1002/sim.7309 article EN Statistics in Medicine 2017-05-03

The World Trade Center (WTC) attacks on 11 September 2001 created a hazardous environment with known and suspected carcinogens. Previous studies have identified an increased risk of prostate cancer in responder cohorts compared the general male population.

10.1136/oemed-2021-107405 article EN cc-by-nc Occupational and Environmental Medicine 2021-09-10

Objective: To determine if World Trade Center (WTC) exposure is associated with hearing loss. Methods: Logistic regression to evaluate the immediate impact of WTC and parametric survival analysis assess longitudinal outcomes. Results: Those arriving on morning September 11, 2001 had elevated odds low-frequency (odds ratio [OR]: 1.24; 95% confidence interval [CI]: 1.04 1.47) high-frequency (OR: 1.16; CI: 1.02 1.31) loss at their first post-September examination. Longitudinally, participants...

10.1097/jom.0000000000001717 article EN Journal of Occupational and Environmental Medicine 2019-09-20

Abstract Purpose: The World Trade Center (WTC) attack of September 11, 2001 created an unprecedented environmental exposure to known and suspected carcinogens. High incidence multiple myeloma precursor conditions has been reported among first responders the WTC disaster. To expand on our prior screening studies, characterize genomic impact potential carcinogens in debris, we were motivated perform whole-genome sequencing (WGS) recovery workers who developed a plasma cell disorder after...

10.1158/1078-0432.ccr-20-2245 article EN Clinical Cancer Research 2021-01-27

Abstract Background A recent study of World Trade Center (WTC)‐exposed firefighters and emergency medical service workers demonstrated that elevated thyroid cancer incidence may be attributable to frequent testing, resulting in the identification asymptomatic tumors. We expand on by comparing among three groups: WTC‐exposed rescue/recovery enrolled a New York State (NYS) WTC‐medical monitoring treatment program (MMTP); not an MMTP (non‐MMTP); NYS population. Methods Person‐time began...

10.1002/ajim.23277 article EN American Journal of Industrial Medicine 2021-07-18

Peripheral neuropathy can result from numerous conditions including metabolic disorders, inflammatory disease, or exposure to environmental biological toxins. We analyzed questionnaire data 9239 Fire Department of the City New York (FDNY) World Trade Center (WTC)-exposed firefighters and emergency medical service workers (EMS) evaluate association between work at WTC site subsequent peripheral symptoms using validated Diabetic Neuropathy Symptom (DNS) score. grouped population into an...

10.3390/ijerph16101727 article EN International Journal of Environmental Research and Public Health 2019-05-16
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