- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Lung Cancer Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Tracheal and airway disorders
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Occupational exposure and asthma
- Sperm and Testicular Function
- Ultrasound in Clinical Applications
- Respiratory and Cough-Related Research
- Eosinophilic Disorders and Syndromes
- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Cardiac Valve Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Histiocytic Disorders and Treatments
- Cardiovascular Issues in Pregnancy
- Acute Ischemic Stroke Management
- Sarcoidosis and Beryllium Toxicity Research
Hospital de São João
2016-2025
Universidade do Porto
2021-2024
Centro Hospitalar de Vila Nova de Gaia
2024
Universidade Federal do Ceará
2014-2023
Hospital Pedro Hispano
2022
Centro Hospitalar do Porto
2017-2021
Universidade Federal de São Paulo
2011
Hospital of St. Francis Xavier
2010
Hospital Infantil Albert Sabin
2003
Hypersensitivity pneumonitis (HP) is an interstitial lung disease with diverse clinical features that can present a fibrotic phenotype similar to idiopathic pulmonary fibrosis (IPF) in genetically predisposed individuals. While several single nucleotide polymorphisms (SNPs) have been associated IPF, the genetic factors contributing HP (fHP) remain poorly understood. This study investigated association of
Aims: Interstitial lung disease (ILD) represents a common complication of connective tissue diseases (CTD). Early detection ILD is critical since patients often remain asymptomatic during the initial stages. While numerous studies have proposed various ultrasound protocols for evaluation, we find these to be time-consuming in our clinical practice. The aim this study introduce concise protocol screening pulmonary fibrosis. Methods: We conducted prospective observational pilot involving 28...
Background: Carpal tunnel syndrome (CTS) has emerged as an early indicator of cardiac amyloidosis (CA) caused by transthyretin-associated (ATTR) mutations, possibly linked to adverse cardiovascular outcomes. This case series examines the relationship between idiopathic CTS and CA imaging diagnosis. Methods: Twenty-two patients from cross-sectional study CarPoS (NCT05409833) were included. These underwent physical evaluation, laboratory exams, electrocardiography, echocardiography, magnetic...
Fibrotic hypersensitivity pneumonitis (fHP) is associated with significant morbidity and mortality. Interstitial lung disease-gender-age-physiology (ILD-GAP) performance in fHP outside the initial cohort was never performed.To assess ILD-GAP index's ability to predict mortality a Portuguese of patients analyse whether other clinical variables add value.Retrospective analysis two ILD centres. The baseline index calculated. Survival analysed months; primary outcome. Univariate multivariate...
Morbidity remains high among patients who undergo successful mechanical thrombectomy (MT) for anterior circulation large vessel occlusion (LVO). Stress hyperglycemia worsens the prognosis after acute ischemic stroke (AIS), but aggressively treating does not improve outcome. There is no consensus on how to best manage glycemia AIS. Glycemic variability (GV) reflects glycemic fluctuations over time and could be culprit. We aimed elucidate GV impacts outcome of AIS treated with MT.
Forecast of success with testicular sperm extraction and intracytoplasmic injection (ICSI) remains unknown, as predictive factors have rarely been studied. We evaluated the association among possible a successful biopsy clinical pregnancy. A consecutive sample men submitted to open in S. João Hospital was used. Patient's age, medical history, volume, spermogram, genetic testing, endocrinologic results, results pregnancy information were collected. From 113 included, it retrieve spermatozoa...
Hydatid disease, or echinococcal is a parasitic infestation caused by the larval stage of Echinococcus tapeworm and it primarily affects liver lung but involvement other organs also possible secondary to peritoneal seeding hematogeneous dissemination. We describe rare case extensive abdominal with lesions affecting liver, peritoneum, lesser omentum, requiring aggressive surgical intervention. Complementary diagnostic exams were crucial reach diagnosis evaluate extension disease.
Hereditary hemorrhagic telangiectasia or Osler-Weber-Rendu syndrome is a rare autosomal dominant vascular disorder characterized by epistaxis, mucocutaneous telangiectasias, and arteriovenous malformations affecting various organs systems. The liver commonly involved organ (74% of patients with hereditary telangiectasia), although symptomatic disease quite infrequent. In cases, clinical manifestations relate most to the predominant type shunting present (arteriovenous, arterioportal,...
Dorsal pancreatic agenesis is a very rare congenital anomaly. Unilateral renal agenesis, on the other hand, relatively common anomaly, although its etiology not fully understood. Renal and embryologic development appears to be nonrelated. We report case of 34-year-old man who was referred our hospital for evaluation cholestasis microalbuminuria. Ultrasound magnetic resonance imaging examinations showed empty right fossa absence neck, body, tail. Our second dorsal unilateral in young male patient.
IntroductionThe outbreak of a highly infectious respiratory disease – COVID-19 - has spread globally and novel type coronavirus (SARS-CoV-2) was identified as its cause. Chest CT findings have been described an aid for diagnosis management. We aimed to describe the imaging characteristics in group patients while we also intended assess if any these radiological features were associated with short-term prognosis.Materials methodsCT examinations from 164 consecutive at least one positive...
Tetralogy of Fallot is known as the most common cyanotic congenital heart disease and has a prevalence 10% all diseases. Although many other anomalies may coexist, association tetralogy hypertrophic cardiomyopathy extremely rare. We report this in 15-month-old female, since birth, her first hospital admission for diagnosis treatment recurring crises. In addition, review literature problems related to provided.
Inflammatory myofibroblastic tumor is a rare benign that affects most commonly children and young adults. In the lung, it comprises less than 1% of all neoplasms. The authors describe clinical, radiological, pathologic features 2 cases incidentally discovered pulmonary inflammatory tumors.
Inflammatory fibroid polyps are rare, benign pseudotumors of the gastrointestinal tract unknown etiology, which may rarely present as bowel intussusception and obstruction. The authors describe clinical, radiologic, pathologic features 2 patients with ileal inflammatory presenting small intussusception.
Progressive pulmonary fibrosis (PPF) comprise a heterogeneous group of lung disorders associated with high morbidity and mortality. The <i>MUC5B</i> promoter variant rs35705950 is common genetic great developing idiopathic (IPF). As IPF fibrotic hypersensitivity pneumonitis (fHP) present phenotypic resemblances, we aimed to analyze the role in molecular pathways linked PPF. Herein, taking advantage our extensive PPF patients' cohort, found that frequency GT TT genotypes was dramatically...
Although coronary angiography (CA) is the gold standard for allograft vasculopathy (CAV) screening, non-invasive modalities have arisen as potential alternatives, such computed tomography (CCTA). CCTA also quantifies plaque burden, which may influence medical treatment. From January 2021 to April 2022, we prospectively included heart transplant recipients who performed a first-line method CAV detection in single center. Clinical, CCTA, and CA data were collected. 38 patients included, 60.5%...