A5054711540- Prenatal Screening and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Parvovirus B19 Infection Studies
- Genomic variations and chromosomal abnormalities
- Cancer Genomics and Diagnostics
- Economic and Environmental Valuation
- Trauma and Emergency Care Studies
- Global Public Health Policies and Epidemiology
- Fetal and Pediatric Neurological Disorders
- Trauma Management and Diagnosis
- COVID-19 epidemiological studies
- Diagnosis and treatment of tuberculosis
- Obesity, Physical Activity, Diet
- Traumatic Brain Injury Research
- Respiratory viral infections research
- Cystic Fibrosis Research Advances
- HIV/AIDS Impact and Responses
- Hip and Femur Fractures
- Influenza Virus Research Studies
- Bone health and osteoporosis research
- Vector-Borne Animal Diseases
- Abdominal Trauma and Injuries
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Healthcare Policy and Management
Université Laval
2012-2023
Institut National d'Excellence en Santé et en Services Sociaux
2023
University of Alberta
2017-2018
Boston University
2016
Hôpital de l'Enfant-Jésus
2014
Abstract A patient-level Markov decision model was used to simulate a virtual cohort of 500,000 women 40 years old and over, in relation osteoporosis-related hip, clinical vertebral, wrist bone fractures events. Sixteen different screening options three main scenario groups were compared: (1) the status quo (no specific national prevention program); (2) universal primary program; (3) treatment program based on 10-year absolute risk fracture. The outcomes measured total directs costs from...
Background: Tuberculosis (TB) remains a global health challenge. Recent studies have compared active case-finding (ACF) with passive (PCF) and various ACF strategies, assessing diagnostic yield, treatment outcomes, cost-effectiveness, overall TB control impact. However, evidence fragmented due to methodological heterogeneity. Methods: To assess how compares PCF different strategies in improving detection, T control, we conducted an umbrella review of systematic reviews meta-analyses...
Early detection of cystic fibrosis (CF) by newborn screening (NBS) reduces the rate avoidable complications. NBS protocols vary jurisdiction and cost effectiveness these different is debated.To compare various CF options.A Markov model was built to simulate CF-NBS options for a hypothetical program over 5-year time horizon assuming its integration into an existing universal program. simulated were based on combination tests between two commonly used immunoreactive trypsinogen (IRT) cutoffs...
A high-quality diet is associated with a reduced of risk chronic disease and all-cause mortality. In this study, we assessed changes in quality the economic burden Canadian population between 2004 2015. We used prevalence-based cost-of-illness approach. first calculated using Healthy Eating Index-Canada-2010 (HEI-C-2010) 24-hour recall data from Community Health Surveys (CCHS) on nutrition (CCHS cycle 2.2 CCHS-NU 2015). then retrieved relative risks HEI-2010 quintiles for diseases...
Atrial fibrillation (AF) is the most common form of heart arrhythmia and a leading cause stroke systemic embolism. Chronic anticoagulation recommended for preventing those complications. Our study aimed to compare cost/utility (CU) three main options: 1) standard warfarin dosing (SD-W) 2) dosage under guidance CYP2C9 VKORC1 genotyping (GT-W) 3) dabigatran 150 mg twice day.A Markov state transition model was built simulate expected C/U dabigatran, SD-W GT-W therapy prevention thromboembolism...
Background A point‐of‐care rapid test ( POCRT ) may help early and targeted use of antiviral drugs for the management influenza infection. Objective (i) To determine whether treatment based on a is cost‐effective and, (ii) to thresholds key parameters (sensitivity, specificity cost) at which based‐strategy appears be cost effective. Methods An hybrid « susceptible, infected, recovered SIR » compartmental transmission Markov decision analytic model was used simulate cost‐effectiveness in...
Policy-making in public health has great socio-economical consequences and must be done using the best available knowledge on possible options. These processes are often too complex to evaluated through analytical methods, such that computer simulations way produce quantitative evaluations of their performances. For purpose, we proposing a complete software infrastructure for simulation processes. This stack includes generic population-based simulator called SynCHroNous Agent-...
Quantitative approaches for eliciting preferences new interventions are mostly conducted by patients and rarely policymakers. This study aimed to quantify the of pregnant women policymakers regarding addition a test prenatal screening programs detecting chromosomal abnormalities.A discrete choice experiment was measure respondents' test. A seven-attribute instrument built based on interviews with The data were analyzed using robust conditional logistic regression nested logit models.In...
Abstract Background Non-invasive prenatal testing (NIPT) using cell-free fetal DNA in maternal plasma is a high accurate test for screening Down syndrome. Although it has been reported to be cost effective as contingent test, evidence about its budget impact lacking. Objective To evaluate, computer simulations, the of implementing NIPT Quebec Program Trisomy 21. Methods A semi-Markov analytic model built simulate into current 21 public Prenatal Screening, Serum Integrated (SIPS). Comparisons...
To determine the cost-effectiveness of addition chromosomal anomalies detectable by non-invasive prenatal screening (NIPS), in a programme targeting common aneuploidies.
Introduction In 2019, the Québec provincial health technology assessment body (INESSS) recommended that lung cancer screening with low-dose computed tomography (LDCT) be accessible in only within context of an evaluation ‘real-world’ care setting. Based on this recommendation, ministry (MSSS) decided, 2020, to implement a pilot project and conduct formal evaluation, partnering clinical leader (principal investigator), participating hospitals, public agency (INSPQ) INESSS. The goal is...
Abstract Background In an accountable world, being able to take into account the value given by relevant stakeholders intervention that could be offered population is considered as desirable. DCE approach particularly suited for measurement of such values in field prenatal care. Yet, studies screening have focused mainly on pregnant women and their care providers but neglected another key actor, decision-makers. The objective study was develop a instrument applicable decision-makers,...