A5074596478- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Gestational Diabetes Research and Management
- Pregnancy-related medical research
- Infant Development and Preterm Care
- Neonatal and Maternal Infections
- Neonatal and fetal brain pathology
- Anesthesia and Pain Management
- Cardiovascular Issues in Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Bariatric Surgery and Outcomes
- Maternal Mental Health During Pregnancy and Postpartum
- Global Maternal and Child Health
- Streptococcal Infections and Treatments
- COVID-19 Impact on Reproduction
- Ultrasound in Clinical Applications
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and Medication Impact
- Pneumonia and Respiratory Infections
- Neuroscience of respiration and sleep
Ljubljana University Medical Centre
2016-2025
University of Ljubljana
2012-2025
Eurocontrol
2024
Clinical Trial Investigators
2021-2023
KU Leuven
2020
St. Joseph's Hospital and Medical Center
2009-2016
Institute Of Perinatology Obstetrics And Gynaecology
2013
Biotherapy of Genetic Diseases, Inflammatory Disorders and Cancers
2011
Institute of Cytology
2011
<h3>Importance</h3> The benefits of surfactant administration via a thin catheter (minimally invasive therapy [MIST]) in preterm infants with respiratory distress syndrome are uncertain. <h3>Objective</h3> To examine the effect selective application MIST at low fraction inspired oxygen threshold on survival without bronchopulmonary dysplasia (BPD). <h3>Design, Setting, and Participants</h3> Randomized clinical trial including 485 gestational age 25 to 28 weeks who were supported continuous...
Abstract Stillbirth rates have stalled or increased in some European countries during the last decade. We investigate to what extent time-trends and between-country differences stillbirth are explained by changing prevalence of advanced maternal age teenage pregnancies multiple births. analysed data on stillbirths live births multiplicity from 2010 2021 25 using Kitagawa decomposition separate rate into compositional components. Rates significantly decreased six countries, but two. Changes...
ABSTRACT Objective To evaluate lung and cardiac ultrasound for the assessment of fluid tolerance responsiveness before after delivery in pregnant women with severe pre‐eclampsia (PE). Methods This was a prospective observational study singleton PE healthy term controls. Lung echo comet score (ECS), which denotes amount extravascular water, obtained using 28‐rib interspaces technique. The echocardiographic E/e′ ratio, measured by pulsed‐wave tissue Doppler, used as marker diastolic left...
The long-term effects of surfactant administration via a thin catheter (minimally invasive therapy [MIST]) in preterm infants with respiratory distress syndrome remain to be definitively clarified.
There are wide disparities in neonatal mortality rates (NMRs, deaths <28 days of life after live birth per 1000 births) between countries Europe, indicating potential for improvement. Comparing country-specific patterns births and with low can facilitate the development effective intervention strategies.
To evaluate associated factors for preeclampsia in twin gestations and to compare incidences of pregnancy complications among pregnancies with vs. without preeclampsia.We performed a case-control study using population dataset delivered after 24 weeks gestation, Slovenia, between 1997 2009. Cases were complicated by controls cases matched gestational age, parity, chorionicity.We identified 181 (4.7%) 3885 twins 542 controls. High pre-pregnancy body mass index (BMI) diabetes significantly...
Introduction Universal screening for the detection of group B streptococcus (GBS) colonization in pregnant women was recently introduced Slovenia. The aim our study to determine whether self-collection rectovaginal swabs is a valid alternative collection by healthcare workers (HCWs). Methods A prospective, multicenter conducted between June and November 2023. total 227 (aged 20 44 years) from University Medical Center Ljubljana ( n = 136), Novo mesto Community Health 48) Trebnje 43) were...
Bacterial vaginosis (BV) is associated with various adverse pregnancy outcomes. It usually diagnosed via microscopy. Semi-quantitative relative culture (SRC) was investigated as a complementary diagnostic method to determine the prevalence of BV and its association preterm birth preterm, premature rupture membranes (PPROM) in pregnant women Slovenia. We examined 3437 consecutive vaginal swabs from during five-year period were able link results 2531 The isolates identified using MALDI-TOF,...
Regular physical activity during pregnancy is associated with several maternal and neonatal health benefits. However, most studies focus on specific forms of exercise in low-risk populations, limiting generalizability. To investigate associations between regular singleton perinatal outcomes using a national registry. A population-based cohort study was conducted data from the Slovenian National Perinatal Information System (2013-2022), which included 190,331 pregnancies. defined as any form...
Background and Objectives: Remifentanil is a potent synthetic μ-opioid receptor agonist known for its rapid onset ultrashort duration of action, making it popular choice intravenous labor analgesia. The analgesic effectiveness remifentanil patient-controlled analgesia (Remifentanil-PCA) may vary based on the stage parity, potentially influencing satisfaction with This study aimed to evaluate degree pain reduction achieved remifentanil-PCA, considering different cervical dilations in both...
To examine pre-gravid body mass index (BMI) and gestational BMI change impact on preeclampsia diabetes mellitus (GDM).Retrospective population-based cohort study. Data from Slovenian National Perinatal Information System were analyzed for the period 2002-2011. Three singleton controls matched by parity maternal age to each twin pregnancy delivered at >36 weeks. Student's t test was used compare in different groups (p < 0.05 significant).2046 6138 pregnancies included. Twin patients with or...
Objectives Internationally, the 10-Group Classification System (TGCS) has been used to report caesarean section rates, but analysis of other outcomes is also recommended. We now aim present TGCS as a method assess labour and delivery using routine collection perinatal information. Design This research methodological study describe use TGCS. Setting Stavanger University Hospital (SUH), Norway, National Maternity Dublin, Ireland Slovenian Perinatal Database (SLO), Slovenia. Participants 9848...
To examine the proportion of iatrogenic births among all preterm over a 26-year period.A registry-based survey deliveries between 1987 and 2012 analyzed by onset labor: spontaneous with intact membranes, premature rupture membranes (PPROM) or iatrogenic. Stratification into categories gestation (22 weeks to 27 6 days, 28 31 32 33 34 36 days) was performed. Preterm birth rates were using Mantel-Haenszel linear-by-linear association χ2-test (P<0.05 significant). Logistic regression used...
Objective: To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. Methods: A registry-based survey pregnancies delivered during 2003 2012. We used best clinical estimate zygosity based on concept that all monochorionic twins are and unlike-sex pairs dizygotic, thus excluding same-sex dichorionic gestations for which cannot be ascertained grounds. Study cohorts were with or without preeclampsia gestational hypertension....
To examine the impact of pre-pregnancy obesity on adverse outcomes in twin compared to singleton pregnancies.Dichorionic gestations with maternal body mass index >30 were matched three controls. Both obese groups (1:3) non-obese Rates preeclampsia, gestational diabetes, cesarean section, and preterm birth compared.One hundred eighty-nine dichorionic pregnancies mothers 567 mothers, mothers. The latter 1701 singletons. Preeclampsia was more common both twins singletons (odds ratio (OR) 3.95,...