Mohammad Sarfi

ORCID: 0000-0003-2724-1528
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Research Areas
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Bladder and Urothelial Cancer Treatments
  • RNA modifications and cancer
  • Bacterial Identification and Susceptibility Testing
  • MicroRNA in disease regulation
  • Pluripotent Stem Cells Research
  • RNA Research and Splicing
  • Ferroptosis and cancer prognosis
  • Urinary Tract Infections Management
  • Parkinson's Disease Mechanisms and Treatments
  • Neuroethics, Human Enhancement, Biomedical Innovations
  • Therapeutic Uses of Natural Elements
  • Neurological disorders and treatments
  • Plant and Fungal Interactions Research
  • Antibiotic Resistance in Bacteria
  • Cancer, Hypoxia, and Metabolism
  • Extracellular vesicles in disease
  • Biomedical Ethics and Regulation
  • Nuclear Receptors and Signaling
  • Magnesium in Health and Disease
  • Autophagy in Disease and Therapy

Tehran University of Medical Sciences
2017-2021

Semnan University of Medical Sciences
2018

Bladder cancer (BC) is the sixth most common malignancy in men and 17th women. Exosomal long non-coding RNAs (lncRNAs) have been defined as a novel biomarker for BC. The aim of this study to evaluate clinical significance urine exosomal PVT-1, ANRIL PCAT-1 BC patients with tumors classified T1 or T2. Exosomes were isolated from healthy donors, then characterized according their shape, size, exosome markers by Electron Microscopy, Dynamic light scattering, Western blotting. lncRNAs extraction...

10.17179/excli2019-1683 article EN PubMed 2020-01-01

Background: Klebsiella pneumoniae as an opportunistic pathogen can be the cause of a range nosocomial and community - acquired infections. Many virulence factors help these bacteria overcome immune system various diseases. K1 K2 capsular antigens, also magA, wcaG, rmpA are well known K. factors. has been revealed to have ability acquire resistance many antibiotics, which treatment failure. Objectives: This study aimed at determining prevalence rmpA, Capsular type K1, K2, TEM, SHV in...

10.5812/jjm.63637 article EN Jundishapur Journal of Microbiology 2018-06-09

Stroke is the third leading cause of mortality worldwide. One factors that affect occurrence stroke can be attributed to changes in levels trace elements. Accumulating evidence has been shown magnesium, as an important element, a new predictor stroke. We aimed determine Mg ischemic patients comparison with those having hemorrhagic type. This study was conducted on 447 patients. Demographic characteristics patients, severity, and risk such hypertension, heart disease, diabetes mellitus,...

10.22088/cjim.11.1.83 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-01-01

Parkinson's disease (PD) is one of the most common neurodegenerative diseases (ND). Studies have demonstrated that biochemical markers an association with PD. We aimed to investigate including calcium, vitamin D, alkaline phosphatase (ALP), parathormone (PTH), and phosphorous This study was conducted on 139 PD patients 100 healthy individuals. Serum levels phosphorous, ALP, PTH D were evaluated. Furthermore, student's t-test logistic regression models used by SPSS. The mean calcium (9.4±0.7...

10.22088/cjim.11.1.28 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-01-01

Tumor cell growth and survival are the outcomes of communication between tumor cells microenvironment (TME). In other words, greatly affected by interaction adjacent cells. this paper, we review recent advances in studies TME, including metabolic interplays their non-malignant neighbors (peaceful autophagy), trades signaling pathways (approach to most important ones; cytokine pathway, NF-kB intra-tumoral hypoxia, oxidative stress, nitric oxide-depended pathways), miRNAs (as regulatory...

10.2174/2212796814999200925162943 article EN Current Chemical Biology 2020-10-02
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