A5101740351- Ferroptosis and cancer prognosis
- Metastasis and carcinoma case studies
- Elbow and Forearm Trauma Treatment
- RNA Interference and Gene Delivery
- Medical Imaging and Analysis
- Wound Healing and Treatments
- Spine and Intervertebral Disc Pathology
- Bee Products Chemical Analysis
- Traditional Chinese Medicine Studies
- Head and Neck Surgical Oncology
- RNA modifications and cancer
- Shoulder Injury and Treatment
- Seaweed-derived Bioactive Compounds
- Polysaccharides and Plant Cell Walls
- Spinal Fractures and Fixation Techniques
- Natural product bioactivities and synthesis
- Orthopedic Surgery and Rehabilitation
- Gastric Cancer Management and Outcomes
- Freezing and Crystallization Processes
- Management of metastatic bone disease
- Colorectal Cancer Surgical Treatments
- Effects of Radiation Exposure
- Artificial Intelligence in Healthcare and Education
- Cervical and Thoracic Myelopathy
- Glycosylation and Glycoproteins Research
Guangdong Pharmaceutical University
2021-2025
Ministry of Agriculture and Rural Affairs
2024
Zhejiang University
2024
Shanghai First People's Hospital
2022-2023
Shanghai Jiao Tong University
2022-2023
Chongqing Three Gorges University
2023
Community Health Center
2023
First Affiliated Hospital of GuangXi Medical University
2020-2022
Guangxi Medical University
2020-2022
Nanjing General Hospital of Nanjing Military Command
2022
Abstract Broomrape ( Orobanche cumana ) negatively affects sunflower, causing severe yield losses, and thus, there is a need to control O. infestation . Brassinosteroids (BRs) play key roles in plant growth provide resilience weed infection. This study aims evaluate the mechanisms by which BRs ameliorate infection sunflower Helianthus annuus ). Seeds were pretreated with (1, 10, 100 nM) inoculation for 4 weeks under soil conditions. significantly reduced traits, photosynthesis, endogenous...
Background Cuproptosis, a genetic process of copper-dependent cell death linked to mitochondria respiration, demonstrates its correlation with inhibiting tumoral angiogenesis and motility. Recent studies have developed systematic bioinformatics frameworks identify the association cuproptosis tumors but any non-neoplastic diseases. Therefore, against background an increased incidence inflammatory bowel disease (IBD), landscape regulation in IBD is critical need be investigated. Methods The...
Schizophyllum commune ( S. ) fermented supernatant with added Radix Puerariae (SC-RP) showed significant antioxidant activity in our previous work. However, the possible lifespan and healthspan extending capacity of Caenorhabditis elegans C. underlying mechanism were not illuminated. In this study, effect SC-RP on improving stress resistance examined. Additionally, molecular mechanisms explored. Treated at 10 μg/mL, increased by 24.89% P < 0.01). Also, prolonged nematode, including...
Tumor cells with the capability of radiation resistance can escape fate cell death after radiotherapy, serving as main cause treatment failure. Repopulation tumors radiotherapy is dominated by this group residual cells, which greatly reduce sensitivity recurrent to therapy, resulting in poor clinical outcomes. Therefore, revealing mechanism resistant participating tumor repopulation vital importance for cancer patients obtain a better prognosis.Co-expressed genes were searched using genetic...
Chamelauciumols A-I (1-9), nine undescribed dimeric acylphloroglucinol derivatives, were isolated from the aerial parts of Chamelaucium uncinatum. Structurally, compound 1 featured a new carbon skeleton characterized by an unprecedented prenyl-substituted methanodibenzo[b,f][1,5]dioxocin core. Compounds 2 and 3 represented scaffolds, consisting two methylated derivatives linked via prenyl units. 4-9 phloroglucinol dimers with various linkage patterns. The structures absolute configurations...
To increase the production of exopolysaccharides and expand application Schizophyllum commune fermentation liquid, traditional Chinese medicine Radix Puerariae with outstanding biological activity was selected as a culture additive.
Ginseng holds high medicinal and cosmetic value, with stem leaf extracts garnering attention for their abundant bioactive ingredients. Meanwhile, fermentation can enhance the effectiveness of cosmetics. The aim this study was to optimize ginseng produce functional were fermented five different strains lactic acid bacteria. Using 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical (·OH), superoxide anion (O
Objective To identify the most effective fraction of Nanocnide lobata in treatment burn and scald injuries determine its bioactive constituents. Methods Chemical identification methods were used to analyze solutions extracted from using petroleum ether, ethyl acetate, n-butanol a variety color reactions. The chemical constituents extracts identified by ultra-performance liquid chromatography (UPLC)–mass spectrometry (MS). A total 60 female mice randomly divided into following 6 groups: ether...
This study was aimed at increasing the capacity of fermented Tremella fuciformis extracellular polysaccharides (TEPS) for possible functional food applications. Thus, strain varieties, fermentation parameters and purification conditions, in vitro antioxidant activities purified EPS fractions were investigated. An high-yield Tf526 selected, effects seven independent factors (time, temperature, initial pH, inoculum size, shaking speed, carbon, nitrogen source) on yield evaluated. By single...
This study aimed to establish a bidirectional fermentation system using Tremella fuciformis and Acanthopanax trifoliatus promote the transformation utilization of synthesized antioxidant metabolites from supernatant. The effect conditions on total phenolic content was investigated response surface methodology in terms three factors, including temperature (22-28°C), pH (6-8), inoculum size (2-8%, v/v). optimized parameters were: 28°C, 8, an 2%, which led maximum 314.79 ± 6.89 μg/mL...
MicroRNAs (miRNAs) modulate a variety of cellular signaling pathways and play vital role in cell-to-cell communication. The overlapped expression certain miRNA is commonly reported to be related cancers. Therefore, combined detection multiple miRNAs great significance for cancer diagnosis. Herein, we developed FeII4L4 tetrahedron-assisted three-way junction (3WJ) probe, which exhibited higher stability than the normal 3WJ detection. In this method, simultaneous existence miRNA-21 miRNA-144...
To validate tumor volume-based imaging markers for predicting local recurrence-free survival (LRFS) in locoregionally advanced nasopharyngeal carcinoma patients, who underwent induction chemotherapy followed by definitive intensity-modulated radiotherapy.We enrolled 145 patients with stage III-IVA this retrospective study. Pre-treatment volume (Vpre) and late-course (LCV) were measured based on the MRIs scanned before treatment during first 3 days sixth week of radiotherapy, respectively....
Aging plays an essential role in the development for chronic obstructive pulmonary disease (COPD). The aim of this study was to identify and validate potential aging-related genes COPD through bioinformatics analysis experimental validation. Firstly, we compared gene expression profiles aged young patients using two datasets (GSE76925 GSE47460) from Gene Expression Omnibus (GEO), identified 244 different expressed (DEGs), with 132 up-regulated 112 down-regulated. Then, by analyzing data...
Abstract The acetabular retroversion has a moderate incidence of 31–60% in all patients the Perthes disease. It might be caused by posterior wall dysplasia based on recent animal researches. However, some studies support that hemipelvic is main factor for retroversion. primary pathological increasing angle still controversial anatomically. This study aimed to identify whether there children with disease,and find method distinguish version types. Forty unilateral disease who were admitted our...
Abstract The present study aimed to explore the influence of ulnar bow on surgical treatment Bado type I missed Monteggia fracture in children. A retrospective review 28 patients was conducted between November 2010 and June 2020. All were treated with open reduction radial head opening wedge osteotomy without annular ligament reconstruction. Four months (range 1–12 months) mean interval injury onset surgery. average age at time surgery 6.1 years old 2–10 old). maximum (MUB) MUB position...