A5100774504- Tuberculosis Research and Epidemiology
- Respiratory Support and Mechanisms
- Mycobacterium research and diagnosis
- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related gene regulation
- Pneumocystis jirovecii pneumonia detection and treatment
- Pleural and Pulmonary Diseases
- Infectious Diseases and Tuberculosis
- RNA modifications and cancer
- Pediatric health and respiratory diseases
- Epigenetics and DNA Methylation
- Medical Imaging and Pathology Studies
- Cholesterol and Lipid Metabolism
- Diagnosis and treatment of tuberculosis
- Cancer Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Respiratory viral infections research
- Appendicitis Diagnosis and Management
- Maternal and fetal healthcare
- Testicular diseases and treatments
- Neurofibromatosis and Schwannoma Cases
- Autoimmune Bullous Skin Diseases
- Palliative Care and End-of-Life Issues
Tongji University
2008-2025
Shanghai Pulmonary Hospital
2008-2025
Guiyang Medical University
2020-2024
Affiliated Hospital of Guizhou Medical University
2020-2024
Guizhou Provincial People's Hospital
2024
First Affiliated Hospital of Xinjiang Medical University
2021-2022
Xinjiang Medical University
2021-2022
First Affiliated Hospital of Xi'an Jiaotong University
2019-2021
Northwest University
2015-2018
Eulji University
2004-2016
Objective This study evaluates the effectiveness of incorporating Chat Generative Pre-trained Transformer (ChatGPT) into clinical teaching hepatobiliary surgery for undergraduate medical students.
A recent in vitro study showed that the three compounds of antiviral drugs with different mechanisms action (amantadine, ribavirin, and oseltamivir) could result synergistic activity against influenza virus. However, no clinical studies have evaluated efficacy safety combination therapy patients severe illness. total 245 adult who were critically ill confirmed pandemic A/H1N1 2009 (pH1N1) virus infection admitted to one intensive care units 28 hospitals Korea reviewed. Patients required...
ABSTRACT Ultrasound is a non‐invasive, non‐ionizing radiation imaging modality for soft tissues. An incarcerated hernia occurring in the inguinal region accompanied by intestinal rupture can be challenging clinical diagnosis, and ultrasound, with its excellent capabilities, more effective identifying underlying cause. Here, we report case demonstrating how ultrasound identified an rupture, despite atypical symptoms, helped determine indication emergency surgery, which was promptly performed...
Interleukin-18 (IL-18) is a multi-functional cytokine capable of inducing either Th1 or Th2 polarization depending on the immunologic milieu. IL-18 may influence host response to Mycobacterium tuberculosis (M.tb) infection. To investigate relationship between single nucleotide polymorphisms and susceptibility pulmonary in Chinese Han population, gene was sequenced detect examine genotype frequencies 300 patients 702 healthy controls. DNA sequencing revealed three variants: rs1946518,...
Associations of interleukin-10 (IL-10) gene promoter polymorphisms and pleural tuberculosis risk remain unclear. The objective this study was to determine IL-10 at -1082, -819 -592 sites their protein production in fluid (PF) patients with without tuberculosis. the were genotyped using a SNaPshot assay. Protein levels PF measured an enzyme-linked immunosorbent There no significant differences genotype allele frequencies position -1082 between control groups. However, frequency T or A alleles...
Objectives The Liver X receptors (LXRs), receptor A (LXRA) and B (LXRB), regulate lipid metabolism antimicrobial response. LXRs have a crucial role in the control of Mycobacterium tuberculosis (M.tb). Lacking mice is more susceptibility to infection M.tb, developing higher bacterial burdens an increase size number granulomatous lesions. We aimed assess associations between single nucleotide polymorphisms (SNPs) risk tuberculosis. Methods sequenced genes detect SNPs examine genotypic...
The aim of the present study was to evaluate diagnostic value interferon-γ release assays for detection active tuberculosis (ATB) in patients previously vaccinated with Bacillus Calmette-Guérin (BCG). In total, 540 underwent T-SPOT.TB test, including 295 pulmonary TB (PTB), 52 extrapulmonary (EPTB), 11 individuals inactive and 182 non-TB cases. Simultaneously, 186 ATB, PTB EPTB cases, 125 tuberculin skin tests (TST). Associations between sensitivity lung lesion severity, positive smear...
A 1D point-prevalence study was performed to describe the characteristics of conventional mechanical ventilation in intensive care units (ICUs). In addition, a survey conducted determine ICUs. prospective, multicenter ICUs at 24 university hospitals. The population consisted 223 patients who were receiving or had been weaned off within past hr. Common indications for initiation included acute respiratory failure (66%), exacerbation chronic (15%) (including tuberculosis-destroyed lung [5%]),...
ABSTRACT A multiplex method using the SNaPshot technique was developed to screen for six common mycobacterial species: Mycobacteria tuberculosis , M. avium intracellulare chelonae kansasii and gordonae . total of 468 clinical isolates were subjected analysis presence species by method. Of isolates, 464 (99.15%) could be correctly identified this assay. The is a promising discriminatory tool rapid accurate identification frequently encountered species.
The CapitalBio Mycobacterium identification microarray system is a rapid for the detection of tuberculosis. performance this was assessed with 24 reference strains, 486 tuberculosis clinical isolates, and 40 samples then compared to "gold standard" DNA sequencing. showed highly concordant results 100% 98.4% complex (MTC) nontuberculous mycobacteria (NTM), respectively. sensitivity specificity array isolates were 99.6% 100%, respectively, direct samples, overall 52.5%. It sputum, 16.7%...
Background Coronary heart disease has become the leading cause of death in developed countries, and dyslipidemia is closely associated with risk cardiovascular disease. Dyslipidemia caused by abnormal regulation several genes signaling pathways, influenced mainly genetic variation. AMFR, FBXW7, INSIG1, INSIG2 , MBTPS1 are lipid metabolism. In a recent GWAS study, GRINA gene been reported to be dyslipidemia, but its molecular mechanism not thoroughly investigated. The correlation between DNA...
Infiltration of sarcoid granuloma in old cutaneous scars is one the uncommon manifestations sarcoidosis. Here, we report case a 47-year-old female who presented with swelling and irritation 5 scars. She had acquired these 9 years ago traffic accident. An incisional scar biopsy revealed noncaseating granulomas consistent High-resolution CT (HRCT) right paratracheal, both hilar, paraaortic, subcarinal lymphadenopathy without any nodular densities lung fields. Successful regression inflammation...