- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Systemic Lupus Erythematosus Research
- Inflammatory mediators and NSAID effects
- Retinal and Macular Surgery
- Sarcoidosis and Beryllium Toxicity Research
- Melanoma and MAPK Pathways
- Cerebral Venous Sinus Thrombosis
- CNS Lymphoma Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Retinal Development and Disorders
- Drug-Induced Ocular Toxicity
- Lymphoma Diagnosis and Treatment
- Corneal surgery and disorders
- Vascular Tumors and Angiosarcomas
- Corneal Surgery and Treatments
- Neurological Disorders and Treatments
- Advancements in Transdermal Drug Delivery
- Salivary Gland Disorders and Functions
University of Perugia
2015-2025
Azienda Ospedaliera di Perugia
2015-2017
Sorbonne Université
2017
Purpose: To report optical coherence tomography angiography (OCT-A) findings in eyes with ocular sarcoidosis (OS) and to compare these those of fluorescein (FA).Methods: Observational, cross-sectional, case-control study. Patients presenting OS involving the posterior segment were evaluated using FA, structural-OCT OCT-A. OCT-angiograms superficial (SCP) deep (DCP) capillary plexuses choriocapillaris (CC) qualitatively quantitatively analyzed.Results: OCT-A seemed more sensitive than FA...
Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has become indispensable for the management of age-related macular degeneration (AMD). OCTA allows quickly visualizing retinal and choroidal microvasculature, in last years, its use increased clinical practice as well research into pathophysiology AMD. This review provides discussion new technology application intermediate late
Purpose: To evaluate choroidal structural changes in patients with multiple evanescent white dot syndrome (MEWDS) during the acute and recovery stages.Methods: Enhanced-depth imaging optical coherence tomography (EDI-OCT) scans of 16 unilateral MEWDS were acquired stages both eyes. Images binarized ImageJ software to measure subfoveal thickness (CT), total choroid area, luminal area vascularity index (CVI).Results: In stage, CT, CVI significantly higher eyes compared fellow (371.2 ± 101.8 vs...
Purpose: To compare the stability of tear film after instillation eye drops containing hyaluronic acid (HA) or crosslinked (CLHA)-based in patients with Sjögren syndrome-related dry (SSDE). Methods: Forty subjects were included this study and divided into 2 groups: first group (control group) consisted 20 healthy volunteers; second (study constituted suffering from SSDE; before 5, 30, 60 min surface regularity index (SRI) asymmetry (SAI) registered. Results: Comparing HA CLHA, control group,...
To perform an analysis of optical coherence tomography (OCT) abnormalities in patients with MEWDS, during the acute and recovery stages, using enhanced depth imaging-OCT (EDI-OCT).A retrospective case series five MEWDS was included. EDI-OCT imaging evaluated to detect retinal choroidal features.In phase, focal impairment ellipsoid zone external limiting membrane, hyperreflective dots inner choroid, full-thickness increase profile were observed affected eye; disappearance these findings...
Purpose: To evaluate the real-life efficacy and safety of intravitreal dexamethasone implant in uveitis. Methods: This retrospective observational multicentric study included 152 eyes treated exclusively by 358 injections. The main outcome measures change best-corrected visual acuity, central macular thickness, vitreous haze score. Results: Patients were with for edema (51.3%), vitritis (40.1%), (5.3%), other causes (3.3%). mean duration follow-up was 19.0 months. gain acuity during +12.1...
Abstract Purpose To determine the effect of preoperative topical Nepafenac administration on anterior chamber flare after uneventful cataract surgery in healthy subjects. Methods Prospective randomized clinical trial. Seventy‐three eyes 73 patients undergoing routine were to receive (group A) nepafenac (1 mg/ml) or not B) 1 drop 3 times per day for days before surgery. All received same postoperative anti‐inflammatory therapy. Clinical outcome parameters such as best corrected visual acuity,...
To compare, using laser flare meter (LFM), the efficacy of topical nepafenac 0.1, % and diclofenac 0.1% ophthalmic solution in control anterior chamber inflammation after uncomplicated cataract surgery.Patients undergoing phacoemulsification for age-related were recruited. Complete evaluation with visual acuity, slit-lamp examination, endothelial cell density, intraocular pressure, retinal tomography was performed before surgery 1, 15, 30 60 days surgery. Patients randomly assigned to...
To quantitatively assess retinal neovascularizations (RNVs) in proliferative diabetic retinopathy (PDR) before and after photocoagulative laser treatment (PLT) using Optical Coherence Tomography Angiography (OCT-A).Consecutive patients with PDR were examined fluorescein angiography (FA) OCT-A PLT. Baseline after-treatment FA images analyzed to both the RNVs area leakage area. On area, vascular perfusion density (VPD), vessel length (VLD) fractal dimension computed. VPD of full-retina...
To describe the importance of a customized combined systemic and local therapy in management inflammatory choroidal neovascularization (iCNV).Observational retrospective case series.Four iCNV cases, complicating posterior uveitis or panuveitis affecting young patients, are reported. Combination both intravitreal (IVT) drugs represented successful treatment strategy.iCNV is sight-threatening disease which affects mostly people. Customized IVT therapies might represent best therapeutic option...
Lupidi, Marco MD; Fiore, Tito Cerquaglia, Alessio Coscas, Gabriel Cagini, Carlo MDEditor(s): Toth, Cynthia A.; Walter, Scott D.; Finn, Avni P. Author Information
Purpose To determine the efficacy of timolol 0.1% gel in preventing increased intraocular pressure (IOP) after uncomplicated cataract surgery. Methods In this prospective, double-blinded, randomized study were enrolled 70 patients who underwent surgery with phacoemulsification and lens implantation. After surgery, 25 received a single instillation (group A); 20 0.5% eyedrops B); no treatment C). The IOP was measured before (T0) 5 minutes (T1), 2 hours ± 30 (T2), 4 (T3), 24 180 (T4). Results...
ABSTRACT Purpose To compare the 12 months visual and anatomical outcomes of treatment‐naïve neovascular age‐related macular degeneration (nAMD) patients diagnosed by optical coherence tomography angiography (OCT‐A) compared with fluorescein (FA)/indocyanine green (ICGA), after anti‐VEGF treatment in a real‐world setting. Methods Monocentric, observational, parallel‐group study nAMD either FA/ICGA or non‐invasive OCT‐A methods. Patients were treated fixed dosing regimen intravitreal...
Purpose To describe a patient with unilateral hypotonic maculopathy and optic disc edema after spontaneous bulbar perforation of full-thickness scleral defect. Methods An 11-year-old girl underwent buckling surgery. Preoperative postoperative evaluation included optical coherence tomography high-resolution 3T magnetic resonance imaging. Results The defect was covered Tenon capsule sheaths meridional silicone buckle. One year postoperatively, visual acuity macular morphology were completely...